Search results for "ageing"

Selected Elements of Lifestyle and the Level of Functional Fitness in Older Women.

2022

Background: The appropriate level of functional fitness is a very important element for seniors to maintain self-reliance in daily life. The aim of this research was to assess sociodemographic differences, selected elements of lifestyle, and functional fitness in the older residents of social welfare homes and community dwellers Methods: The analysed group comprised 693 women aged 65–79, including 173 subjects living in social welfare homes and 520 community-dwelling women. Basic anthropometric features were measured, and functional fitness was assessed using the Senior Fitness Test. Basic sociodemographic characteristics, as well as data on health self-assessment and selected elements of l…

Volatility of secondary organic aerosol during OH radical induced ageing

2011

The aim of this study was to investigate oxidation of SOA formed from ozonolysis of <i>α</i>-pinene and limonene by hydroxyl radicals. This paper focuses on changes of particle volatility, using a Volatility Tandem DMA (VTDMA) set-up, in order to explain and elucidate the mechanism behind atmospheric ageing of the organic aerosol. The experiments were conducted at the AIDA chamber facility of Karlsruhe Institute of Technology (KIT) in Karlsruhe and at the SAPHIR chamber of Forchungzentrum Jülich (FZJ) in Jülich. A fresh SOA was produced from ozonolysis of <i>α</i>-pinene or limonene and then aged by enhanced OH exposure. As an OH radical source in…

Water diffusion and swelling stresses in ionizing radiation cured epoxies as matrices for carbon fiber composites

2017

Cross-linking polymerization initiated by high energy radiation is a very attractive technique for the production of high performance composite materials. This method in fact offers many advantages compared to conventional thermal curing processes, due to the possibility to operate at mild temperature and in short time, limiting both energy and time consuming [1-2]. High performance composite materials mainly consist of epoxy resins as matrix and carbon fibers as reinforce, due to their excellent properties in terms of thermal and mechanical resistance. An important requirement of such systems for structural applications is their ability to maintain the properties within a fixed range durin…

Mitochondria and Ageing

2018

Mitochondria are the major sites of oxygen utilisation for energy production in cells. Indeed, all the reactions of the Krebs’ Cycle take place in mitochondria and they produce NADH and succinate, which are then oxidised in the respiratory chain. Experiments dating back to the early part of the twentieth century seemed to indicate that at a high rate of oxygen consumption (referred to gram of body weight) was normally associated with a low maximum lifespan. Thus, it was thought that it was the rate of oxygen utilisation that was related to “the rate of living”. However, more recent data pointed out that birds are unique because they combine high rates of oxygen consumption with a high maxim…

High-Speed Machines: Typologies, Standards, and Operation under PWM Supply

2018

This paper presents an overview of the most recent state of the art in the field of high-speed electric machines fed through high-frequency converters. This type of systems is rapidly wide spreading in aeronautical and automotive applications, as well as microturbines. Each typology has its own advantages and downsides, which are analytically presented in this paper. Some types of high-speed electric machines require high-frequency voltage supply, highly stressing the dielectric materials of the winding insulation system. For this reason, in high-speed electric drives, premature failure may occur and a reduction of the total system reliability has been observed in the past years. Such issue…

Evaluation of Green Roof Ageing Effects on Substrate Hydraulic Characteristics

2020

The vegetated substrate of green roofs may undergo various chemical and physical changes with time. Minidisk infiltrometer (MDI) tests were conducted to assess the short-term variations of the near-saturated hydraulic conductivity, K0, in the extensive green roof test plot established at the University of Palermo. Sampling was repeated four times: before planting (Age 0) and then after four months (Age 1), seven months (Age 2) and ten months (Age 3). A total of 144 infiltration tests were conducted at two pressure heads, h0 = −3 cm and h0 = −0.5 cm and infiltration data analysed by the Zhang (Soil Science Society of America Journal 61(4):1024–1030, 1997) model. Both K-3 and K-0.5 underwent …

Immunosenescence, inflammation and Alzheimer’s disease

2012

Abstract Ageing impacts negatively on the development of the immune system and its ability to fight pathogens. Progressive changes in the T-cell and B-cell systems over the lifespan of individuals have a major impact on the capacity to respond to immune challenges. The cumulative age-associated changes in immune competence are termed immunosenescence that is characterized by changes where adaptive immunity deteriorates, while innate immunity is largely conserved or even upregulated with age. On the other hand, ageing is also characterized by “inflamm-ageing”, a term coined to explain the inflammation commonly present in many age-associated diseases. It is believed that immune inflammatory p…

Investigation of genetic factors and molecular targets influencing immunosenescence in Sicilian population: potential approaches for future immunothe…

2021

Age-related changes of NADPH-diaphorase-positive neurons in the rat inferior colliculus and auditory cortex

2007

Nitric oxide (NO) has been implied in age-related changes of the central nervous system (CNS) and the central auditory pathway. The present study was conducted to investigate whether the number of NO-producing cells and their morphometric characteristics in the inferior colliculus (IC) and the auditory cortex (AC) are changed with the increasing age of the subjects. IC and AC sections of adult and senile Wistar rats were studied using the histochemical detection of NADPH-diaphorase activity (NADPH-d), a marker for neurons containing nitric oxide synthase (NOS). Our results showed a decreased area of the somas of NADPH-d-positive neurons in the dorsal cortex (DC) of the IC and a diffuse loss…

Effects of maternal ageing and dietary antioxidant supplementation on ovulation, fertilisation and embryo development in vitro in the mouse.

1999

The present study aims to ascertain whether dietary supplementation with a mixture of vitamins C and E may prevent the maternal-age-associated decrease in both the number of ovulated oocytes after exogenous ovarian stimulation and embryo development in vitro in the mouse. Experimental females were fed a standard diet supplemented with i) high doses of vitamins C and E from the first day of weaning until 12 or 40 weeks of age; or ii) moderate doses of vitamins C and E from the first day of weaning until 12 weeks of age or from 22 to 33 weeks of age. The age-related reduction in ovulation rate was partially prevented by supplementing diet with high doses of vitamins C and E from the first day…