Search results for "aging"
showing 10 items of 10496 documents
Wybrane modele zmutowanych i transgenicznych zwierząt w badaniach mechanizmów starzenia i patologii wiekowej
2016
Alternatywny proces wydłużania telomerów
2016
Optical quality of hyperopic and myopic phakic intraocular lenses
2013
Aims: To assess and compare the optical quality of the myopic and hyperopic implantable collamer lens (ICL) from its wavefront aberrations for different powers and pupil diameters. Settings and Design: Prospective study. Material and Methods: The wavefront aberrations of two myopic (−3 and −6 diopters (D)) and two hyperopic V4b ICLs (+3 and +6D) were measured in vitro . To assess and compare the optical quality of different powers of ICLs, we analyzed the root mean square (RMS) of total higher order aberrations (HOAs), trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration at 3- and 4.5-mm pupil. In addition, the point spread functions (PSFs) of each ICL evaluated were ca…
Impact of Narrow Band Imaging in Pre-Operative Assessment of Suspicious Oral Cavity Lesions: A Systematic Review
2021
Introduction: Narrow band imaging (NBI) is a powerful tool that allows visualizing the mucosal and submucosal vasculature. Among the available diagnostic techniques, NBI is one of the most valid for early detection of oral squamous cell carcinoma (OSCC). Materials and Methods: We carried out a bibliographic search in PubMed, Scopus and Web of Science databases using relevant keywords. Articles selected were screened by two independent authors based on inclusion and exclusion criteria. Nine papers were singled out according to the eligibility criteria and included in this review. We investigated the articles for pooled sensitivity, specificity, accuracy, positive predictive value and negativ…
Voimaharjoittelun vaikutukset dynaamiseen ja staattiseen tasapainoon nuorilla ja ikääntyneillä
2017
Tasapainolle ei ole olemassa universaalia määritelmää mutta se tiedetään, että sitä kontrolloivat useat eri mekanismit. Ikääntyminen aiheuttaa siinä heikkenemistä, joka aiheutuu muutoksista sekä sensorisissa että motorisissa prosesseissa. Kaatumisesta aiheutuneiden vammojen määrä kasvaa koko ajan ikääntyneillä. Heidän onkin havaittu pärjäävän nuoria huonommin sekä staattisissa että dynaamisissa testeissä mutta dynaamisissa testeissä ero on vieläkin suurempi. Erityisesti dynaamisten ominaisuuksin tutkiminen on tärkeää sillä staattiset testit eivät välttämättä paljasta tasapaino-ongelmia tai ikääntymiseen liittyviä eroja yhtä hyvin kuin dynaamiset testit. Tämän tutkimuksen suoritti loppuun 4 …
Towards a Guidance System to Aid in the Dosimetry Calculation of Intraoperative Electron Radiation Therapy
2015
In Intraoperative Electron Radiation Therapy (IOERT), the lack of specific planning tools limits its applicability, the need for accurate dosimetry estimation and application during the therapy being the most critical. Recently, some works have been presented that try to overcome some of the limitations for establishing planning tools, though still an accurate guidance system that tracks, in real-time, the applicator and the patient is needed. In these surgical environments, the acquisition of an accurate 3D shape of the patient’s tumor bed in real-time is of high interest, as current systems make use of a 3D model acquired before the treatment. In this paper, an optical-based system is pre…
Coronavirus-related health literacy and perceived restrictiveness of protective measures among community-dwelling older persons in Finland
2021
Abstract Background Older people with limited health literacy may encounter difficulties in finding relevant information on COVID-19, understanding its relevance, and complying with recommended protective measures. Complying with such recommendations has required older as well as younger persons to change their daily lives in ways that have reduced their opportunities for engaging in many activities meaningful to them. Aims To find out from what sources older people have obtained information on protective measures, the level of their coronavirus-related health literacy (CHL), and whether CHL is associated with their perceptions of the restrictiveness of coronavirus-related protective measur…
Comment on “Fatigability: A Prognostic Indicator of Phenotypic Aging”
2021
A Polygenic Risk Score for Hand Grip Strength Predicts Muscle Strength and Proximal and Distal Functional Outcomes among Older Women
2022
Purpose Hand grip strength (HGS) is a widely used indicator of overall muscle strength and general health. We computed a polygenic risk score (PRS) for HGS, and examined, whether it predicted muscle strength, functional capacity and disability outcomes. Methods Genome-wide association study summary statistics for HGS from the Pan-UK Biobank was utilized. PRSs were calculated in the Finnish Twin Study on Aging (N = 429 women, 63–76 years). Strength tests included HGS, isometric knee extension, and ankle plantar flexion strength. Functional capacity was examined with the Timed Up and Go, six-minute and 10-meter walk tests, and dual-task tests. Disabilities in the basic (ADL) and instrumental …