Search results for "aging"

showing 10 items of 10496 documents

Autofluorescence imaging for recurrence detection in skin cancer postoperative scars

2020

This clinical study is a first attempt to use autofluorescence for recurrence diagnosis of skin cancer in postoperative scars. The proposed diagnostic parameter is based on a reduction in scar autofluorescence, evaluated in the green spectral channel. The validity of the method has been tested on 110 postoperative scars from 56 patients suspected of non-melanoma skin cancer, with eight patients (13 scars) available for the repeated examination. The recurrence diagnosis within a scar has been made after two subsequent autofluorescence check-ups, representing the temporal difference between the scar autofluorescence amplitudes as a vector. The recognition of recurrence has been discussed to r…

medicine.medical_specialtySkin NeoplasmsGeneral Physics and AstronomyScarsVector angle01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology010309 opticsClinical studyCicatrix0103 physical sciencesmedicineHumansGeneral Materials SciencePostoperative scarsPostoperative monitoringStage (cooking)business.industryOptical Imaging010401 analytical chemistryGeneral EngineeringGeneral Chemistrymedicine.disease0104 chemical sciencesAutofluorescenceRadiologySkin cancermedicine.symptombusinessJournal of Biophotonics
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S2k guidelines for Merkel cell carcinoma (MCC, neuroendocrine carcinoma of the skin) – update 2018

2019

Merkel cell carcinoma (MCC, ICD-O M8247 / 3) is a rare malignant primary skin tumor with epithelial and neuroendocrine differentiation. The neoplastic cells share many morphological, immunohistochemical and ultrastructural characteristics with Merkel cells of the skin. The diagnosis of MCC is rarely made on clinical grounds. Histological and immunohistochemical studies are usually required to confirm the clinical suspicion. Given the frequent occurrence of occult lymph node metastasis, sentinel lymph node biopsy should be performed once distant metastasis has been ruled out by cross-sectional imaging. Primary tumors without evidence of organ metastases are treated with complete surgical exc…

medicine.medical_specialtySkin Neoplasmsmedicine.medical_treatmentSentinel lymph nodeMedizinAntineoplastic AgentsDermatologyNeuroendocrine differentiation030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineBiopsyCarcinomaHumansMedicineNeoadjuvant therapyAgedNeoplasm Stagingmedicine.diagnostic_testbusiness.industryMerkel cell carcinomaPrognosismedicine.diseaseNeoadjuvant TherapyCarcinoma Merkel CellRadiation therapymedicine.anatomical_structureLymphatic MetastasisImmunotherapyRadiologyNeoplasm Recurrence LocalCognition DisordersbusinessMerkel cell
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Ionising radiation and lens opacities in interventional physicians: results of a German pilot study

2019

We assessed the feasibility of an epidemiological study on the risk of radiation-related lens opacities among interventional physicians in Germany. In a regional multi-centre pilot study associated with a European project, we tested the recruitment strategy, a European questionnaire on work history for the latter dosimetry calculation and the endpoint assessment. 263 interventional physicians and 129 non-exposed colleagues were invited. Questionnaires assessed eligibility criteria, risk factors for cataract, and work history relating to occupational exposure to ionising radiation, including details on type and amount of procedures performed, radiation sources, and use of protective equipmen…

medicine.medical_specialtySlit lampbusiness.industryScheimpflug principlePublic Health Environmental and Occupational HealthGeneral Medicinemedicine.diseasePupil030218 nuclear medicine & medical imagingClinical trial03 medical and health sciences0302 clinical medicineCataracts030220 oncology & carcinogenesisEpidemiologyDosimetryMedicineMedical physicsWork historybusinessWaste Management and DisposalJournal of Radiological Protection
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EPR dosimetry intercomparison using smart phone touch screen glass

2014

International audience; This paper presents the results of an interlaboratory comparison of retrospective dosimetry using the electron paramagnetic resonance method. The test material used in this exercise was glass coming from the touch screens of smart phones that might be used as fortuitous dosimeters in a large-scale radiological incident. There were 13 participants to whom samples were dispatched, and 11 laboratories reported results. The participants received five calibration samples (0, 0.8, 2, 4, and 10 Gy) and four blindly irradiated samples (0, 0.9, 1.3, and 3.3 Gy). Participants were divided into two groups: for group A (formed by three participants), samples came from a homogene…

medicine.medical_specialtySmart phoneMass casualty eventStatistics as TopicBiophysicsEPR dosimetry[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]EPR Dosimetry Elecron Paramagnetic Resonance in phone touch screen glass.01 natural sciencesRetrospective dosimetry030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineTest material0103 physical sciencesmedicineHumansDosimetryMedical physicsRadiometryGeneral Environmental Science010302 applied physicsRadiationDosimeterbusiness.industryElectron Spin Resonance SpectroscopyRadiological emergencySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Critical levelHomogeneousCalibrationEpr dosimetryGlassbusinessNuclear medicine[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processingCell Phone
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Up-to-date imaging review of paediatric soft tissue vascular masses, focusing on sonography

2019

The purpose of this article is to provide an up-to-date overview on imaging of paediatric vascular soft tissue masses, including both neoplastic and non-neoplastic lesions. We describe the-often challenging-imaging diagnosis-mainly performed by ultrasound (and secondarily by MRI) and differential diagnosis of vascular soft tissue lesions in children. We underline how important it is to determine whether a vascular anomaly has a regional vascular origin, or if there are other entities, ranging from benign to malignant lesions, which have flow-signal or blood degradation products. Even though clinical examination and patient's history are the first and indispensable steps in the initial diagn…

medicine.medical_specialtySoft Tissue NeoplasmsVascular malformationPhysical examination030218 nuclear medicine & medical imagingVascular anomalyDiagnosis Differential03 medical and health sciences0302 clinical medicinePseudo-tumourmedicineHumansRadiology Nuclear Medicine and imagingSoft Tissue NeoplasmChildChildrenUltrasonographyNeuroradiologymedicine.diagnostic_testbusiness.industryVascular tumourUltrasoundVascular malformationSoft tissueInterventional radiologySoft tissueGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingVascular NeoplasmsPaediatric030220 oncology & carcinogenesisRadiologyTumourDifferential diagnosisbusinessHumanLa radiologia medica
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Primary intra and extradural solitary fibrous tumor/hemangiopericytoma of thoracic spine with paravertebral intrathoracic spread: Case report and rev…

2020

Abstract Solitary fibrous tumors/hemangiopericytomas (SFTs/HPCs), constitute 1% of all CNS tumors. Spinal SFTs/HPCs are extremely rare. To date, few retrospective studies and case reports of primary spinal SFTs/HPCs have been published in the literature. We report clinical and radiological presentation, surgical treatment, and post-operative outcome at three years follow-up of a rare case of primary spinal intra and extradural SFT/HPC of thoracic spine with dumbbell shaped paravertebral intrathoracic spread and multidirectional erosion of the bone. A 73-year-old female presented with progressive lower limbs weakness and hypoesthesia below the rib cage. MRI showed an irregular isointense T5-…

medicine.medical_specialtySolitary fibrous tumorlcsh:SurgerySolitary Fibrous Tumor/HemangiopericytomaSchwannomalcsh:RC346-429030218 nuclear medicine & medical imagingHemangiomaMeningioma03 medical and health sciences0302 clinical medicineDumbbell TumorsmedicineAngiosarcomalcsh:Neurology. Diseases of the nervous systemHemangiopericytomabusiness.industryPrimary Spine Tumorslcsh:RD1-811medicine.diseaseSurgeryNeurology (clinical)RadiologyChordomaDifferential diagnosisbusiness030217 neurology & neurosurgeryInterdisciplinary Neurosurgery
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Meningiomas of the Space of the Cavernous Sinus

1996

During the years 1985 to 1992, we encountered 59 patients with meningiomas involving the space of the cavernous sinus. In 29 of these patients, meningiomas were primarily located within the space of the cavernous sinus and were operated on without mortality and with low morbidity. A small subtemporal surgical approach was favored, which allowed initial tumor resection from the posterior aspect, where the Parkinson's triangle is wide, thus avoiding the additional morbidity of large-scale approaches. According to the relationships of the all-important cranial nerves passing within the lateral wall of the cavernous sinus, we divided the primary intracavernous meningiomas into four types, which…

medicine.medical_specialtySphenoid SinusMeningiomaPostoperative ComplicationsMeningeal NeoplasmsmedicineHumansCranial Nerve NeoplasmsNeoplasm InvasivenessNerve functionCranial Nerve InjuriesNeurologic Examinationmedicine.diagnostic_testbusiness.industryCranial nervesCranial NervesCavernous Sinus MeningiomaMagnetic resonance imagingAnatomymedicine.diseaseMagnetic Resonance ImagingCranial Nerve DiseasesSurgerymedicine.anatomical_structurePeripheral nervous systemCranial Nerve InjuryCavernous sinusCavernous SinusSurgeryNeurology (clinical)Neoplasm Recurrence LocalMeningiomabusinessFollow-Up StudiesNeurosurgery
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Arachnoidalzyste der Keilbeinhöhle

1998

BACKGROUND Arachnoid cysts of the paranasal sinus are rare. They have not been described yet in the sphenoid sinus. PATIENT AND METHOD Microscopic-endoscopic endonasal surgery of the sphenoid sinus was performed on a 34-year-old female with a history of chronic headaches and a suspected mucocele of the sphenoid sinus in computed tomography (CT) and magnetic resonance imaging (MRI) studies. An extended arachnoid cyst was found in the enlarged sphenoid sinus, which was obliterated with collagen, fibrin glue, and abdominal fat. RESULTS There were no complications after the operation, and 12 months later the patient is still free of symptoms. CONCLUSION Arachnoidal cysts present in CT and MRI a…

medicine.medical_specialtySphenoidal sinusmedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentMagnetic resonance imagingMicrosurgerymedicine.diseaseSurgerymedicine.anatomical_structureOtorhinolaryngologyArachnoid cystotorhinolaryngologic diseasesAbdominal fatMedicineMucoceleFibrin gluebusinessSinus (anatomy)Laryngo-Rhino-Otologie
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Spiral-CT und 3 D-Rekonstruktion des Tracheobronchialbaumes zur Auswahl geeigneter Doppellumentuben vor Einzellungenbeatmung

1997

Purpose To assess the potential of 3-D spiral CT in the selection of adequate double-lumen tubes (DLT) for one-lung-ventilation. Materials and methods 3-D spiral CT of eight different DLTs was performed with standardized acquisition parameters: section thickness 4 mm, table speed 6 mm/s, increment 3 mm and standardised thresholds, window settings and magnification zoom. The accuracy was confirmed by measuring 3-D objects on screen and original DLTs by vernier caliper. 3-D spiral CT was performed in 20 patients preoperatively with slice thickness 4-8 mm, pitch 1-1.5, increment 4-8 mm. To select the adequate DLT size the 3-D reconstructions of the patient's tracheobronchial tree and of the DL…

medicine.medical_specialtySpiral CT ScansMaterials sciencebusiness.industrySlice thicknessMagnificationSurgerymedicineSuperimpositionCalipersRadiology Nuclear Medicine and imagingTomographyNuclear medicinebusinessSpiral ctDouble lumen tubeRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Prediction of N0 Irradiated Rectal Cancer Comparing MRI Before and After Preoperative Chemoradiotherapy

2017

Background: The prediction of lymph node status using MRI has an impact on the management of rectal cancer, both before and after preoperative chemoradiotherapy. Objective: The purpose of this study was to maximize the negative predictive value and sensitivity of mesorectal lymph node imaging after chemoradiotherapy because postchemoradiation node-negative patients may be treated with rectum-sparing approaches. Design: This was a retrospective study. Settings: The study was conducted at a tertiary care hospital. Patients: Sixty-four patients with locally advanced rectal cancer who underwent preoperative chemoradiotherapy and MRI for staging and the assessment of response were evaluated. Mai…

medicine.medical_specialtyStagingColorectal cancerNegative predictive valuePreoperative care03 medical and health sciences0302 clinical medicineMagnetic resonance imagingmedicineRectal cancer; Chemoradiotherapy; Lymph node; Staging; Magnetic resonance imaging; Negative predictive value.Rectal cancerLymph nodeMesorectalmedicine.diagnostic_testbusiness.industryGastroenterologyMagnetic resonance imagingGeneral MedicineChemoradiotherapymedicine.diseasemedicine.anatomical_structure030220 oncology & carcinogenesisPredictive value of testsAdenocarcinoma030211 gastroenterology & hepatologyLymph nodeRadiologybusinessChemoradiotherapy
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