Search results for "aging"

showing 10 items of 10496 documents

The lyon clinical olfactory test: validation and measurement of hyposmia and anosmia in healthy and diseased populations.

2011

 ; International audience; The LCOT is a self-administered test designed to assess olfactory deficits. Altogether, 525 subjects contributed to the validation. Elderly participants were well represented in this sample. In a validation study (study 1), 407 healthy and 17 anosmic volunteers between 15 and 91 years of age underwent threshold, supraliminal detection, and identification testing. Cutoff values for normosmia and hyposmia were calculated and applied in a second study in a group of patients with smell complaints and in a group of Alzheimer patients with age-matched controls. Incidence of smell deficit was estimated at 5.6% in the healthy population of study 1, and at 16% in the elder…

medicine.medical_specialtyValidation studyArticle SubjectOlfactory disorderAnosmialcsh:SurgeryMédecine humaine et pathologieOlfactionTest validityAudiologyBioinformaticsaging;development;olfaction;olfactory disorder;Alzheimer's disease;cognitive impairment03 medical and health sciences0302 clinical medicineHyposmiamedicineFood and Nutrition[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs030223 otorhinolaryngologyolfactory disorderdevelopmentcognitive impairmentbusiness.industryIncidence (epidemiology)Healthy populationaging[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologielcsh:RD1-811Alzheimer's diseaselcsh:Otorhinolaryngologylcsh:RF1-547[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie[ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory OrgansAlimentation et NutritionNeurosciences (Sciences cognitives)Human health and pathology[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiemedicine.symptombusiness030217 neurology & neurosurgeryResearch ArticleNeuroscienceolfaction
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Experimentelle Untersuchungen zur Reproduzierbarkeit von Ensemble-gemittelten elektromyographischen Ganganalysedaten im Bereich der experimentellen u…

2004

With suitable application and signal processing methods, surface electromyography is a comparatively simple instrument for investigating the temporal pattern of the muscular activity of a walking subject. The influence of changes both in the external experimental conditions (e.g. orthopedic shoe design) and in the human locomotor system (due to disease or therapy) on the individual muscular gait characteristics can be documented in this way. The usefulness of this kind of investigation is basically limited by the reproducibility of the gait analytical findings of the subject, who is examined at different times with unchanged bodily state and under identical experimental conditions unchanged…

medicine.medical_specialtyValidation studyReproducibilitymedicine.diagnostic_testEnsemble averagingBiomedical EngineeringData interpretationElectromyographyPhysical medicine and rehabilitationGait (human)Gait analysisOrthopedic surgerymedicineMathematicsBiomedizinische Technik/Biomedical Engineering
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Recommendations for Multimodal Noninvasive and Invasive Screening for Detection of Extracranial Venous Abnormalities Indicative of Chronic Cerebrospi…

2014

Under the auspices of the International Society for Neurovascular Disease (ISNVD), four expert panel committees were created from the ISNVD membership between 2011 and 2012 to determine and standardize noninvasive and invasive imaging protocols for detection of extracranial venous abnormalities indicative of chronic cerebrospinal venous insufficiency (CCSVI). The committees created working groups on color Doppler ultrasound (US), magnetic resonance (MR) imaging, catheter venography (CV), and intravascular US. Each group organized a workshop focused on its assigned imaging modality. Non-ISNVD members from other societies were invited to contribute to the various workshops. More than 60 neuro…

medicine.medical_specialtyVascular MalformationsVenographyVertebral veinMultimodal ImagingNOmedicineHumansRadiology Nuclear Medicine and imagingVascular DiseasesUltrasonography Doppler ColorUltrasonography Interventionalmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingInterventional radiologyPhlebographyVascular surgeryNeurovascular bundlemedicine.diseaseMagnetic Resonance ImagingCerebrovascular DisordersCatheterChronic cerebrospinal venous insufficiencyVenous InsufficiencyRadiology Nuclear Medicine and imagingRadiologybusinessCardiology and Cardiovascular MedicineJournal of Vascular and Interventional Radiology
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Früh- und Spätergebnisse der perkutanen transluminalen Angioplastie (PTA) beim Diabetiker

1991

Results of 127 iliac and femoropopliteal transluminal angioplasties in 97 diabetic patients are presented. Patients who had undergone iliac (n = 70), femoral (n = 41), and popliteal (n = 16) angioplasties for stenoses up to 15 cm long were followed up for 6-60 months. In diabetic patients presenting with only claudication or adequate runoff, the 5-year iliac patency rate was 76% and the femoral patency rate was 60%; these results were comparable with those found in non-diabetic patients. For limb salvage, 3-year patency rates were 66% for iliac, 37% for femoral, and 37% for popliteal angioplasties, and 5-year patency rates were 29% for iliac, 7% for femoral, and 0% for popliteal angioplasti…

medicine.medical_specialtyVascular diseasebusiness.industryLimb salvageFemoral arterymedicine.diseasePeripheralSurgeryStenosismedicine.anatomical_structuremedicine.arteryDiabetes mellitusmedicineRadiology Nuclear Medicine and imagingmedicine.symptomClaudicationbusinessArteryRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Vasodilator Stress CMR and All-Cause Mortality in Stable Ischemic Heart Disease

2020

Abstract Objectives This study explored the association of ischemic burden, as measured by vasodilator stress cardiovascular magnetic resonance (CMR), with all-cause mortality and the effect of revascularization on all-cause mortality in patients with stable ischemic heart disease (SIHD). Background In patients with SIHD, the association of ischemic burden, derived from vasodilator stress CMR, with all-cause mortality and its role for decision-making is unclear. Methods The registry consisted of 6,389 consecutive patients (mean age: 65 ± 12 years; 38% women) who underwent vasodilator stress CMR for known or suspected SIHD. The ischemic burden (at stress first-pass perfusion imaging) was com…

medicine.medical_specialtyVasodilator stressmedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentHazard ratioIschemiaMagnetic resonance imagingPerfusion scanningDisease030204 cardiovascular system & hematologyRevascularizationmedicine.diseaseConfidence interval030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineInternal medicinemedicineCardiologyRadiology Nuclear Medicine and imagingCardiology and Cardiovascular MedicinebusinessJACC: Cardiovascular Imaging
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Transverse Sinus Stenosis in Refractory Chronic Headache Patients: An Observational Study

2019

Background: Transverse sinus stenosis is a common brain MRI finding in chronic migraine (CM) and chronic tension-type headache (CTTH) patients in clinical practice; however, its clinical and diagnostic role is unclear. The aim of the study is to determine the frequency of transverse sinus stenosis in these headache patients resistant to preventive treatments and to verify whether this is a useful finding for identifying patients with intracranial hypertension. Methods: This is an observational study. Patients with refractory CM and CTTH underwent a 3T-magnetic resonance venography (MRV) before cerebrospinal fluid (CSF) opening pressure measurement. Transverse sinus stenosis was determined u…

medicine.medical_specialtyVenographylcsh:RC346-429030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineCerebrospinal fluidChronic Migrainechronic headacheInternal medicinemedicineRisk factorlcsh:Neurology. Diseases of the nervous systemSinus (anatomy)Original Researchmedicine.diagnostic_testbusiness.industrysinus stenosisrefractory headachemedicine.diseaseComorbidityStenosismedicine.anatomical_structureNeurologyConcomitantCardiologyNeurology (clinical)businessidiopathic intracranial hypertension030217 neurology & neurosurgeryMRIFrontiers in Neurology
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Transpenile Venenokklusion zur Therapie der erektilen Impotenz

1989

In 15 of 18 patients, 2 of them with previous surgery, transpenile venoablation was performed for treatment of erectile dysfunction due to cavernous leakage. In 4 this was combined with retrograde venooclusion via the internal iliac vein. In 4 patients normal erectile status could be obtained. In 3 other patients erections became possible with use of intracavernous vasoactive agents. In two only mild amelioration, and in two others no change of erectile dysfunction were obtained. Follow-up studies are yet missing in 3 patients. Complications of the procedure were not observed.

medicine.medical_specialtyVenous occlusionbusiness.industrymedicine.medical_treatmentSclerosing Solutionsmedicine.diseaseSurgerymedicine.anatomical_structureErectile dysfunctionVasoactivemedicineInternal iliac veinRadiology Nuclear Medicine and imagingEmbolizationbusinessPenisRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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1177 The additive prognostic value of end-systolic pressure-volume relation by CMR in patients with with known or suspected coronary artery disease

2020

Abstract Background The variation between rest and peak stress end-systolic pressure-volume relation is an afterload-independent index of left ventricular contractility. This index is easily obtained during routine stress echocardiography but can be derived also during a stress cardiovascular magnetic resonance (CMR) exam, that is the gold standard for the quantification of biventricular volumes. Purpose The aim of this study was to assess for the first time the prognostic value ofdelta rest-stress ESPVR (DESPVR) by dipyridamole stress-CMR in patients with known or suspected coronary artery disease (CAD). Methods One hundred and sixty-six consecutive patients (37 females, main age 61.96 ± 1…

medicine.medical_specialtyVentricular End-Systolic Volumebusiness.industryGeneral Medicinemedicine.diseaseDipyridamoleCoronary artery diseaseBlood pressureLinear gingival erythemaHeart failureInternal medicinemedicineStress EchocardiographyCardiologyRadiology Nuclear Medicine and imagingSystoleCardiology and Cardiovascular Medicinebusinessmedicine.drugEuropean Heart Journal - Cardiovascular Imaging
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Interrater reliability of ultrasound in the diagnosis of sialolithiasis

2019

 The aim of this study was to assess the interrater reliability of ultrasound for diagnosing sialolithiasis. A total of 100 consecutive patients with signs of obstructive sialadenopathy were evaluated. The patients all underwent ultrasound examinations in a standardized manner conducted by one specialist with extensive experience in the management of salivary gland disorders and proficiency in head and neck ultrasonography. The video recordings were sent to six colleagues with comparable experience without providing any further information about the patients' medical history and physical examination. The overall agreement between the seven observers was substantial, with a κ of 0.765 for th…

medicine.medical_specialtyVideo RecordingPhysical examination030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePatient informationMedicineHumansRadiology Nuclear Medicine and imagingMedical historyHead and neckUltrasonographyObserver VariationSalivary Gland Calculi030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryUltrasoundReproducibility of Resultsmedicine.diseaseInter-rater reliabilityStenosisRadiologyUltrasonographybusiness
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Dropped head as an unusual presenting sign of myasthenia gravis.

2007

Prominent or isolated weakness of cervical extensor muscles is a relatively rare clinical sign. Commonly, this is known as "dropped-head syndrome". This abnormal flexion of the head may occur in a variety of neuromuscular diseases and in a few non-neurological disorders as well. The case we describe concerns a 61-year-old woman with dropped-head syndrome as the unique complaint of myasthenia gravis.

medicine.medical_specialtyWeaknessNeurologyAbnormal flexionDermatologyNeck MusclesMyasthenia GravismedicineHumansNeuroradiologyMuscle Weaknessbusiness.industryGeneral MedicineRecovery of FunctionMiddle Agedmedicine.diseaseDermatologyMagnetic Resonance ImagingMyasthenia gravisPsychiatry and Mental healthTreatment OutcomeDropped headCervical VertebraeFemaleNeurology (clinical)NeurosurgeryCholinesterase Inhibitorsmedicine.symptombusinessHeadSign (mathematics)Pyridostigmine BromideNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
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