Search results for "alignment"

showing 10 items of 627 documents

Characterizations of adenovirus type 41 isolates from children with acute gastroenteritis in Japan, Vietnam, and Korea.

2004

ABSTRACT Genetic and antigenic characterizations of 70 strains of adenovirus type 41 (Ad41), isolated between 1998 and 2001 from children in Japan, Vietnam, and Korea, were done by DNA restriction enzyme (RE) analysis, sequencing analysis, and monoclonal antibody (MAb)-based enzyme-linked immunosorbent assay (ELISA). Eight genome types were observed in the present study, among which D25, D26, D27, and D28 were novel genome types. These eight genome types were divided into two genome-type clusters (GTCs) based on phylogenetic analysis of the hypervariable regions (HVRs) of the hexon. GTC1 includes D1, D25, D26, D27, and D28, and the GTC2 contains D4, D12, and D22. The amino acid homologies a…

Microbiology (medical)Molecular Sequence DataRestriction MappingEnzyme-Linked Immunosorbent AssayGenome ViralBiologyGenomePolymerase Chain ReactionViruslaw.inventionRestriction mapJapanlawPhylogeneticsVirologyHumansAmino Acid SequenceChildPeptide sequencePolymerase chain reactionPhylogenyDNA PrimersKoreaPhylogenetic treeBase SequenceSequence Homology Amino AcidAdenoviruses HumanVirologyHypervariable regionGastroenteritisVietnamAcute DiseaseSequence AlignmentJournal of clinical microbiology
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Molecular Analysis of the VP7, VP4, VP6, NSP4, and NSP5/6 Genes of a Buffalo Rotavirus Strain: Identification of the Rare P[3] Rhesus Rotavirus-Like …

2003

ABSTRACT We report the detection and molecular characterization of a rotavirus strain, 10733, isolated from the feces of a buffalo calf affected with diarrhea in Italy. Strain 10733 was classified as a P[3] rotavirus, as the VP8* trypsin cleavage product of the VP4 protein revealed a high amino acid identity (96.2%) with that of rhesus rotavirus strain RRV (P5B[3]), used as the recipient virus in the human-simian reassortant vaccine. Analysis of the VP7 gene product revealed that strain 10733 possessed G6 serotype specificity, a type common in ruminants, with an amino acid identity to G6 rotavirus strains ranging from 88 to 98%, to Venezuelan bovine strain BRV033, and Hungarian human strain…

Microbiology (medical)SerotypeDiarrheaRotavirusGenes ViralSwinevirusesReassortmentMolecular Sequence DataReoviridaeCattle DiseasesBiologyViral Nonstructural Proteinsmedicine.disease_causePolymerase Chain ReactionVirusBirdsFecesfluids and secretionsRotavirusVirologyGenotypemedicineAnimalsHumansAmino Acid SequenceHorsesGeneAntigens ViralAllelesPhylogenyGeneticsViral Structural ProteinsSequence Homology Amino Acidvirus diseasesbiology.organism_classificationVirologyMacaca mulattaDiarrheaCapsid ProteinsCattlemedicine.symptomSequence Alignment
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Lineage diversification and recombination in type-4 human astroviruses.

2013

Abstract Human astroviruses (HAstVs) are important enteric pathogens and can be classified genetically and antigenically into eight types. During surveillance of HAstVs in Italy, type-4 HAstVs were detected only sporadically and found to cluster into two distinct genetic groups. Upon sequence analysis of the 3′ end of the polymerase gene (ORF1b) and of the full-length ORF2, the 2008 type-4 HAstV strains were characterised as a novel ORF2 genetic lineage, designated as 4c. The 2008 type-4 HAstVs also shared the ORF1b gene with similar HAstV-4c strains detected globally, thus displaying a conserved ORF1b/ORF2 asset. By interrogation of the databases, this novel lineage 4c accounted for 60.8% …

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaLineage (genetic)Sequence analysisMolecular Sequence DataSequence alignmentBiologyMicrobiologyAstrovirusFecesOpen Reading FramesAstrovirus Epidemiology Genotyping Italy Viral gastroenteritisPhylogeneticsAstroviridae InfectionsGenetic variationGeneticsHumansAmino Acid SequenceMolecular BiologyGenotypingGeneEcology Evolution Behavior and SystematicsPhylogenyGeneticsRecombination GeneticBase SequenceSequence Homology Amino AcidSequence Analysis RNAvirus diseasesGenetic Variationbiology.organism_classificationRNA-Dependent RNA PolymeraseGastroenteritisInfectious DiseasesRNA ViralCapsid ProteinsSequence AlignmentMamastrovirusInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
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Simultaneous identification of campylobacters and prediction of quinolone resistance by comparative sequence analysis.

1997

Comparative sequence analysis of a 30-bp segment in the quinolone resistance-determining region of campylobacters not only allows for the detection of base changes associated with resistance but also is a powerful tool for species identification based on silent mutations.

Microbiology (medical)Silent mutationDNA Bacterialmedicine.drug_classSequence analysisSequence alignmentBiologymedicine.disease_causeDNA gyrasePolymerase Chain Reactionlaw.inventionAnti-Infective AgentsSpecies SpecificitylawmedicinePolymerase chain reactionAntibacterial agentGeneticsMutation4-QuinolonesSequence Homology Amino AcidCampylobacterDrug Resistance MicrobialSequence Analysis DNAQuinoloneDNA Topoisomerases Type IIDNA GyraseSequence AlignmentResearch Article
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Systematics of Mepraia (Hemiptera-Reduviidae): cytogenetic and molecular variation.

2009

The haematophagous insects of the subfamily Triatominae (Hemiptera-Reduviidae) have great epidemiological importance as vectors of Trypanosoma cruzi, the causative agent of Chagas disease. Mepraia was originally described as a monotypic genus comprised of Mepraia spinolai, distributed along coastal areas of northern Chile (from Region I to the Metropolitan Region). Recently, some M. spinolai populations have been ranked as a new species named Mepraia gajardoi. Several populations along the distribution range of the genus were sampled, and genetic differentiation was studied based upon the analysis of three molecular markers: cytogenetics (karyotype and chromosome behaviour during meiosis us…

Microbiology (medical)SystematicsMaleMitochondrial DNAMolecular Sequence DataMicrobiologyPolymerase Chain ReactionMepraiaCytogeneticsIntergenic regionGeneticsAnimalsChagas DiseaseChileGonadsMolecular BiologyRibosomal DNAEcology Evolution Behavior and SystematicsPhylogenyGeneticsPolymorphism GeneticbiologyMolecular epidemiologyBase SequenceGeographyChromosomebiology.organism_classificationInsect VectorsInfectious DiseasesReduviidaeEvolutionary biologyDNA IntergenicFemaleTriatominaeSequence AlignmentInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
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Unraveling assemblage, functions and stability of the gut microbiota of Blattella germanica by antibiotic treatment

2020

Symbiosis between prokaryotes and eukaryotes is a widespread phenomenon that has contributed to the evolution of eukaryotes. In cockroaches, two types of symbionts coexist: an endosymbiont in the fat body (Blattabacterium), and a rich gut microbiota. The transmission mode of Blattabacterium is vertical, while the gut microbiota of a new generation is mainly formed by bacterial species present in feces. We have carried out a metagenomic analysis of Blattella germanica populations, treated and non-treated with two antibiotics (vancomycin and ampicillin) over two generations to (1) determine the core of bacterial communities and potential functions of the gut microbiota and (2) to gain insight…

Microbiology (medical)functional resiliencePopulationDIVERSITYINSECTSlcsh:QR1-502ZoologyBACTERIAL COMMUNITYGut floraMicrobiologydigestive systemantibioticslcsh:Microbiology03 medical and health sciencesBlattabacteriumSymbiosiseducationFecesOriginal Research030304 developmental biology0303 health scienceseducation.field_of_studyScience & TechnologyendosymbiosisEndosymbiosisbiologygut microbiota030306 microbiologyMIDGUTbiology.organism_classificationVANCOMYCINALIGNMENTCOCKROACHBlattella germanicaMetagenomicsEVOLUTIONARYLife Sciences & BiomedicineBacteriaRESISTANCE
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Oxygen as a morphogenic factor in sponges: expression of a tyrosinase gene in the sponge Suberites domuncula

2004

Sponges live in a symbiotic relationship with microorganisms, especially bacteria. Here we show, using the demosponge Suberites domuncula as a model, that the sponge expresses the enzyme tyrosinase which synthesizes diphenols from monophenolic compounds. It is assumed that these products serve as carbon source for symbiotic bacteria to grow.

MicroorganismTyrosinaseMolecular Sequence DataGeneral Physics and AstronomyMicrobiologyDemospongeStructural BiologyAnimalsHumansGeneral Materials ScienceAmino Acid SequenceSymbiosisPhylogenychemistry.chemical_classificationbiologyMonophenol MonooxygenaseCell Biologybiology.organism_classificationPoriferaOxygenSuberites domunculaSpongeEnzymechemistryBiochemistrySequence AlignmentBacteriaSymbiotic bacteriaMicron
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Tracing the first steps of American sturgeon pioneers in Europe

2008

Abstract Background A Baltic population of Atlantic sturgeon was founded ~1,200 years ago by migrants from North America, but after centuries of persistence, the population was extirpated in the 1960s, mainly as a result of over-harvest and habitat alterations. As there are four genetically distinct groups of Atlantic sturgeon inhabiting North American rivers today, we investigated the genetic provenance of the historic Baltic population by ancient DNA analyses using mitochondrial and nuclear markers. Results The phylogeographic signal obtained from multilocus microsatellite DNA genotypes and mitochondrial DNA control region haplotypes, when compared to existing baseline datasets from extan…

Mitochondrial DNAEvolutionMolecular Sequence DataPopulationZoologyBiologyDNA MitochondrialPolymerase Chain ReactionEvolution MolecularSturgeonQH359-425AnimalseducationAtlantic OceanPhylogenyEcology Evolution Behavior and Systematicseducation.field_of_studyBase SequenceChimeraFishesSequence Analysis DNAbiology.organism_classificationhumanitiesEuropePhylogeographyGenetics PopulationAncient DNAHaplotypesHabitatMicrosatelliteSequence AlignmentMicrosatellite RepeatsResearch ArticleAtlantic sturgeonBMC Evolutionary Biology
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Characterization of the length polymorphism in the A + T-rich region of the Drosophila obscura group species

1993

In the twelve Drosophila obscura group species studied, belonging to the affinis, obscura, and pseudoobscura subgroups, the mitochondrial DNA length ranges from 15.8 to 17.2 kb. This length polymorphism is mainly due to insertions/deletions in the variable region of the A + T-rich region. In addition, one species (D. tristis) possess a tandem duplication of a 470-bp fragment that contains the replication origin. The same duplication has occurred at least twice in the Drosophila evolutionary history due to the fact that the repetition is analogous to repetitions found in the four species of the D. melanogaster complex. By comparing the nucleotide sequence of the conserved region in D. ambigu…

Mitochondrial DNAMolecular Sequence DataRestriction MappingDNA RecombinantDNA MitochondrialConserved sequenceSpecies SpecificityMolecular evolutionDrosophilidaeSequence Homology Nucleic AcidGene duplicationGeneticsAnimalsMolecular BiologyEcology Evolution Behavior and SystematicsGeneticsPolymorphism GeneticbiologyBase SequenceAdenineNucleic acid sequencebiology.organism_classificationNucleic Acid ConformationDrosophilaTandem exon duplicationDrosophila obscuraSequence AlignmentPlasmidsThymidine
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Mitochondrial simple sequenze repeats and 12s – rRNA gene reveal two distinct lineages of Crocidura russula (Mammalia, Sorcidae)

2004

A short segment (135 bp) of the control region and a partial sequence (394 bp) of the 12S-rRNA gene in the mitochondrial DNA of Crocidura russula were analyzed in order to test a previous hypothesis regarding the presence of a gene flow disruption in northern Africa. This breakpoint would have separated northeast-African C. russula populations from the European (plus the northwest-African) populations. The analysis was carried out on specimens from Tunisia (C. r. cf agilis), Sardinia (C. r. ichnusae), and Pantelleria (C. r. cossyrensis), and on C. r. russula from Spain and Belgium. Two C. russula lineages were identified; they both shared R2 tandem repeated motifs of the same length (12 bp)…

Mitochondrial DNARange (biology)Lineage (evolution)Crocidura russulaMolecular Sequence DataMtDNASettore BIO/05 - ZoologiaDNA MitochondrialMonophylyAfrica NorthernPhylogeneticsSequence Homology Nucleic AcidGeneticsAnimals12S-rRNA; Crocidura russula; MtDNA; North Africa; SSRs; ZoogeographyGenetics (clinical)PhylogenybiologyBase SequenceEcology12S-rRNAShrewsGenes rRNAbiology.organism_classificationNorth AfricaCrocidura russulaSSRRussulaMitochondriaEuropeGenetics PopulationSister groupEvolutionary biologyRNA RibosomalZoogeographySequence AlignmentSequence AnalysisMicrosatellite Repeats
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