Search results for "alternative"

showing 10 items of 1466 documents

Hepatotoxicity of systemic therapies for unresectable hepatocellular carcinoma

2021

Complementary and alternative medicinebusiness.industryHepatocellular carcinomamedicine.medical_treatmentCancer researchPharmaceutical ScienceMedicinePharmacology (medical)Immunotherapybusinessmedicine.diseaseLiver Cancer International
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Manifiesto de Niños, o la escenificación de la violencia

2019

espanolSin lugar a dudas con Manifiesto de Ninos, el colectivo teatral El periferico de Objetos redobla su apuesta en lo que viene siendo una propuesta estetica altamente arriesgada al ofrecernos algo asi como una “instalacion teatral de la violencia” mediante la utilizacion recrudecida del impacto emocional sobre el espectador. La obra fuerza hasta limites insospechados la tolerancia visual del receptor y plantea la anatomia de una claustrofobica experimental que intenta denunciar la violencia ejercida sobre los ninos. Los resultados de esta experiencia invocan hacia una reflexion sobre una poetica que explora la profunda abyeccion de la pulsion escopica del espectador mediante una organiz…

Complementary and alternative medicinemedia_common.quotation_subjectPharmaceutical SciencePharmacology (medical)ArtHumanitiesmedia_commonCuadernos del Centro de Estudios de Diseño y Comunicación
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Testing for goodness rather than lack of fit of continuous probability distributions.

2021

The vast majority of testing procedures presented in the literature as goodness-of-fit tests fail to accomplish what the term is promising. Actually, a significant result of such a test indicates that the true distribution underlying the data differs substantially from the assumed model, whereas the true objective is usually to establish that the model fits the data sufficiently well. Meeting that objective requires to carry out a testing procedure for a problem in which the statement that the deviations between model and true distribution are small, plays the role of the alternative hypothesis. Testing procedures of this kind, for which the term tests for equivalence has been coined in sta…

Computer scienceStatement (logic)Alternative hypothesisScienceTest StatisticsResearch and Analysis MethodsStatistical InferenceMathematical and Statistical TechniquesStatistical inferenceEconometricsHumansLack-of-fit sum of squaresStatistical MethodsEquivalence (measure theory)Statistical hypothesis testingStatistical DataProbabilityMultidisciplinaryModels StatisticalApplied MathematicsSimulation and ModelingStatisticsQRProbability TheoryProbability DistributionTerm (time)Monte Carlo methodStatistical TheoriesPhysical SciencesProbability distributionMedicineMathematicsAlgorithmsResearch ArticleStatistical DistributionsPLoS ONE
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On general conditional prevision assessments

2009

In this paper we consider general conditional random quantities of the kind $X|Y$, where $X$ and $Y$ are finite discrete random quantities. Then, we introduce the notion of coherence for conditional prevision assessments on finite families of general conditional random quantities. Moreover, we give a compound prevision theorem and we examine the relation between the previsions of $X|Y$ and $Y|X$. Then, we give some results on random gains and, by a suitable alternative theorem, we obtain a characterization of coherence. We also propose an algorithm for the checking of coherence. Finally, we briefly examine the case of imprecise conditional prevision assessments by introducing the notions of…

Conditional random quantities; coherence; conditional prevision assessments; random gain; alternative theorems; algorithms; imprecise assessments; generalized and total coherence.Settore MAT/06 - Probabilita' E Statistica Matematicarandom gainConditional events general conditional random quantitiesgeneral conditional prevision assessments generalized compound prevision theorem generalized Bayes TheoremConditional random quantitiesalgorithmsimprecise assessmentsalternative theoremsgeneralized and total coherencecoherenceconditional prevision assessments
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Third-Generation Solar Cells: Concept, Materials and Performance - An Overview

2019

The large scarcity of natural fuels in earth crust has triggered to search alternative energy reservoirs for the future generation of human life. Because of large abundancy, solar energy is considered as big hope for the future generation energy utilization for commercial as well as home applications. The scientific revolution achieved in synthesis and processing of semiconductor nanomaterials, organic conducting polymers have led into new dimension in fabrication of future-generation solar cells. Reduction in the dimension of semiconductor nanomaterials significantly influences on their structural and optical properties which is helpful for the excellent photon harvesting. Also, their larg…

Conductive polymerFabricationMaterials sciencebusiness.industryPhotovoltaic systemNanotechnologySolar energylaw.inventionNanomaterialslawSolar cellAlternative energyCrystalline siliconbusiness
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Mediation and Private International Law: Improving Free Circulation of Mediation Agreements Across the EU

2016

This paper, commissioned by the European Parliament’s Policy Department for Citizens’ Rights and Constitutional Affairs upon request by the JURI Committee, examines the issues arising in the context of cross-border mediation. Cross-border litigation has increased steadily in recent years in Europe as a consequence of the consolidation of the European unification process. The enactment of Directive 2008/52/EC has certainly led to the presence of mediation legislation in the EU Member States. But many important differences can still be ascertained in relation to the legal framework developed, which affect key aspects of mediation. For mediation to obtain full endorsement by citizens in the fu…

Conflict of lawsParliamentLawmedia_common.quotation_subjectPolitical scienceMember stateLegislationPublic administrationFamily mediationDirectiveEnforcementAlternative dispute resolutionmedia_commonSSRN Electronic Journal
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MicroRNA-Based Therapeutic Perspectives in Myotonic Dystrophy

2019

Myotonic dystrophy involves two types of chronically debilitating rare neuromuscular diseases: type 1 (DM1) and type 2 (DM2). Both share similarities in molecular cause, clinical signs, and symptoms with DM2 patients usually displaying milder phenotypes. It is well documented that key clinical symptoms in DM are associated with a strong mis-regulation of RNA metabolism observed in patient’s cells. This mis-regulation is triggered by two leading DM-linked events: the sequestration of Muscleblind-like proteins (MBNL) and the mis-regulation of the CUGBP RNA-Binding Protein Elav-Like Family Member 1 (CELF1) that cause significant alterations to their important functions in RNA processing. It ha…

Context (language use)miRNA-based drugReviewBioinformaticsMyotonic dystrophyCatalysislcsh:ChemistryInorganic ChemistryMBNL proteinsCELF1microRNADrug DiscoveryMedicineAnimalsHumansPhysical and Theoretical Chemistrylcsh:QH301-705.5Molecular BiologySpectroscopyCELF1 ProteinRna processingmyotonic dystrophymicroRNAbusiness.industryOrganic ChemistryAlternative splicingmiRNA-targeting drugRNA-Binding ProteinsGeneral MedicineGenetic Therapymedicine.diseasePhenotypeComputer Science ApplicationsAlternative SplicingMicroRNAslcsh:Biology (General)lcsh:QD1-999Drug developmentGene Expression Regulationantisense oligonucleotidesbusinessFunction (biology)International Journal of Molecular Sciences
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Positive solutions for nonlinear Robin problems with convection

2019

We consider a nonlinear Robin problem driven by the p-Laplacian and with a convection term f(z,x,y). Without imposing any global growth condition on f(z,·,·) and using topological methods (the Leray-Schauder alternative principle), we show the existence of a positive smooth solution.

ConvectionGeneral Mathematicsnonlinear maximum principlep-LaplacianGeneral Engineering(minimal) positive solutionNonlinear systemEngineering (all)p-LaplacianApplied mathematicsnonlinear regularityMathematics (all)convection termLeray-Schauder alternative principleMathematics
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The pharmacology of the genus Sophora (Fabaceae): An updated review.

2019

Abstract Background The genus Sophora (Fabaceae) represents one of the important medicinal plant genera regarding its chemical constituents and outstanding pharmacological activities. Purpose In this review, we surveyed the latest findings on the bioactivities of different Sophora extracts and isolated phytochemicals during the past 8 years (2011–2019) updating the latest review article in 2011. The aim of this review is to focus on the molecular pharmacology of Sophora species to provide the rationale basis for the development of novel drugs. Results Sophora and its bioactive compounds possess outstanding pharmacological properties, especially as anticancer and anti-inflammatory drugs, in …

Conventional medicineAntifungalSophoramedicine.drug_classPhytochemicalsAnti-Inflammatory AgentsPharmaceutical SciencePharmacologyBiologyAntioxidants03 medical and health sciences0302 clinical medicineAnti-Infective AgentsGenusDrug DiscoverymedicineAnimalsHumans030304 developmental biologyPharmacology0303 health sciencesPlants MedicinalPlant ExtractsMolecular PharmacologyFabaceaebiology.organism_classificationAntineoplastic Agents PhytogenicComplementary and alternative medicineDrug development030220 oncology & carcinogenesisChemical constituentsEthnopharmacologyMolecular MedicineMedicine TraditionalSophoraPhytomedicine : international journal of phytotherapy and phytopharmacology
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La conformación del cooperativismo en Brasil: tendencias y desafíos en el Siglo XXI

2002

The paper deals with the subject of cooperativism focusing on a view of the co-operative system in Brazil, as well as the process of formation and consolidation of the models and the influences of the different aspects of co-operative thought. We then present an analysis of the process of economic modernisation and the transformations in the co-operative system in the 70s to 90s decades, and lastly, we analyse the current tendencies and challenges for cooperativism in Brazil.

Cooperativism Brazil modernisation economic alternatives and employment.jel:G29jel:G20jel:P13CIRIEC-España, revista de economía pública, social y cooperativa
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