Search results for "amina"

showing 10 items of 2711 documents

Synthesis of azoxystrobin transformation products and selection of monoclonal antibodies for immunoassay development

2012

The use of agrochemicals for crop protection may result in the presence of toxic residues in soils and aquatic environments, besides in foodstuffs. Most often just the parent compound is included in the definition of pesticide residue, even though chemicals resulting from biotransformation and degradation routes might also be of toxicological relevance. Azoxystrobin is a broad-spectrum systemic fungicide widely used worldwide to combat pathogenic fungi affecting plants. We herein report the synthesis and detailed chemical characterization of several of the most relevant metabolites and degradates of azoxystrobin. These compounds were further employed as ligands for screening a collection of…

medicine.drug_classStereochemistryFungicideMetaboliteGeneric antibodyEnzyme-Linked Immunosorbent AssayFood ContaminationMetaboliteBuffersToxicologyMonoclonal antibodyMicechemistry.chemical_compoundBiotransformationAntibody SpecificitymedicineAnimalsImmunoassayMolecular Structuremedicine.diagnostic_testPesticide residueChemistryAntibodies MonoclonalGeneral MedicineHydrogen-Ion ConcentrationStrobilurinsFungicides IndustrialFungicidePyrimidinesBiochemistryAzoxystrobinImmunoassayMethacrylatesDegradateHaptenImmunoanalytical methodsToxicology Letters
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Prevalence estimation of celiac disease in the general adult population of Latvia using serology and HLA genotyping

2015

Background: Prevalence estimates for celiac disease (CD) depend on the method used. The role of deamidated gliadin peptide (DGP) and genetic testing in epidemiological studies and diagnostic settings of celiac disease (CD) has still to be established. Objectives: The objective of this article is to assess the prevalence of CD in Latvia by combining serological tests with DQ2.5/ DQ8 testing. Methods: A total of 1444 adults from a randomly selected cross-sectional general population sample were tested by ELISA for tTG IgA, DGP IgA and IgG antibodies (QUANTA Lite, Inova Diagnostics Inc). Samples with tTG IgA 20U were tested for EMA IgA by indirect immunofluorescence assay, and all specimens wi…

medicine.medical_specialty:MEDICINE [Research Subject Categories]Tissue transglutaminasePopulationSerologyChemiluminescent assaysEpidemiologyGenotypePrevalenceCeliac diseaseMedicineDQ2.5/8 genotypeeducationGenotypingGenetic testingeducation.field_of_studyDeamidated gliadin peptidemedicine.diagnostic_testbiologybusiness.industryTissue transglutaminaseGastroenterologynutritional and metabolic diseasesOriginal ArticlesOncologyImmunologybiology.proteinAntibodybusinessUnited European Gastroenterology Journal
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Self-reported symptoms in women with diastasis rectus abdominis: A systematic review

2021

Abstract Introduction Diastasis rectus abdominis (DRA) diagnosis via clinical examination is well defined, however, the assessment of symptoms has been less investigated. Currently, there is also scant knowledge on the consequences of DRA. The aim of this review is to identify the relevant self-reported variables in the study of DRA in women. Methods We performed a systematic review of observational studies through Medline, Embase, and Cochrane Library databases. Studies evaluating the link between DRA and self-reported symptoms were searched using the following terms: "Diastasis rectus abdominis", "Diastasis recti", "Abdominis Rectus Muscle Diastasis", "Questionnaire", "Scale", "Survey", "…

medicine.medical_specialtyAbdominal painDiastasis MuscleRectus AbdominisUrinary incontinencePhysical examinationPelvic Floor DisordersDiagnostic Self Evaluation03 medical and health sciences0302 clinical medicinePelvic floor dysfunctionQuality of lifeBody ImagemedicineHumansDiastasis rectiMuscle Weakness030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryObstetrics and Gynecologymedicine.diseaseLow back painAbdominal PainReproductive Medicine030220 oncology & carcinogenesisQuality of LifeDiastasisPhysical therapyFemaleSelf ReportSymptom Assessmentmedicine.symptombusinessLow Back PainJournal of Gynecology Obstetrics and Human Reproduction
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INTESTINAL INFECTION BY CRYPTOSPORIDIUM IN THREE CHILDREN WITH ABDOMINAL PAIN AND CHRONIC DIARRHOEA

1985

Children infection by Cryptosporidium sp. have been communicated since 1976 usually associated to acute diarrohoeal disease. This protozoa has been isolated recently in SIDA patients with serious illness. Three new cases, the first of spanish pediatric literature, are described in this paper. Children were males; two of them twins. Age ranged 24 to 27 m. All lived in Valencia, and went to infant's school with high stand of living and domestic animal relationship. The most frequent symptom was well located colic abdominal pain with day predominance and 2 months of evolution in the twins. The third case began with abdominal pain and discomfort. Three months before had been treated with Metron…

medicine.medical_specialtyAbdominal painbiologybusiness.industryAnemiaSpiramycinCryptosporidiummedicine.diseasebiology.organism_classificationSurgeryInternal medicineAbdominal examinationPediatrics Perinatology and Child HealthMedicineEosinophiliamedicine.symptombusinessSidaProctitismedicine.drugPediatric Research
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Lymphatic Mesenteric Cyst, a Rare Cause of Surgical Abdominal Pain: Case Report and Review of the Literature

2020

A lymphatic mesenteric cyst (LMC) is a rare clinical entity, of unclear etiopathogenesis, which can arise in the abdominal cavity or retroperitoneum without a clear origin. We describe a case of a 74-year-old male presenting with abdominal pain that was non-specific and non-responsive to medical therapy. Laboratory tests clinical examination were inconclusive while the abdominal computed tomography (CT) scan showed a cystic lesion of the ileal mesentery. We performed an open surgical excision of the lesion with the resolution of clinical symptoms. The lesion resulted to be an LMC at the histological examination. At the five-year CT scan follow-up, we did not record any recurrences. LMCs pre…

medicine.medical_specialtyAbdominal painmesenteric cystlaparoscopyPhysical examinationAbdominal cavity030204 cardiovascular system & hematologyLesionsurgery03 medical and health sciences0302 clinical medicinemedicineLaparoscopymedicine.diagnostic_testbusiness.industryUltrasoundGeneral EngineeringMesenteric cystGastroenterologyabdominal painmedicine.diseasemedicine.anatomical_structureLymphatic systemGeneral SurgeryRadiologymedicine.symptombusinessRadiology030217 neurology & neurosurgeryCureus
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State of the Art-High-Sensitivity Troponins in Acute Coronary Syndromes.

2020

In cases of suspected acute coronary syndrome (ACS), rapid and accurate diagnosis is essential to establish effective evidence-based medical treatment. Patients' history, clinical examination, 12-lead electrocardiogram, and cardiac biomarkers are cornerstones in initial management. Since high-sensitivity cardiac troponins were established, they have markedly expedited and revolutionized rule-in and rule-out pathways of patients with ACS and changed our everyday clinical practice. Thus, they have become an indispensable tool in daily routine in emergency units. This review focuses on historical and contemporary standards in laboratory biomarkers of myocardial injury and discusses their impli…

medicine.medical_specialtyAcute coronary syndromeCardiac biomarkersMyocardial InfarctionPhysical examinationContext (language use)030204 cardiovascular system & hematologySensitivity and SpecificityDiagnosis Differential03 medical and health sciences0302 clinical medicinemedicineHumans030212 general & internal medicineMyocardial infarctionAcute Coronary SyndromeIntensive care medicinebiologymedicine.diagnostic_testMedical treatmentbusiness.industryGeneral Medicinemedicine.diseaseTroponinTroponinbiology.proteinBiomarker (medicine)Cardiology and Cardiovascular MedicinebusinessBiomarkersCardiology clinics
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Characterization of adenosine receptors in guinea-pig isolated left atria

1989

1. The effects of purinergic stimulation on action potential, force of contraction, 86Rb efflux and 45Ca uptake were investigated in guinea-pig left atria. 2. Adenosine exerted a negative inotropic effect which was antagonized by adenosine deaminase but enhanced by dipyridamole. 3. The negative inotropic effect of adenosine was mimicked by 5'-(N-ethyl)-carboxamido-adenosine (NECA) and the isomers of N6-(phenyl-isopropyl)-adenosine, R-PIA and S-PIA. NECA and R-PIA were about 100 times more potent than adenosine, whereas R-PIA was about 100 times more potent than S-PIA. 4. The inotropic effects of adenosine (in the presence of dipyridamole), NECA, R-PIA and S-PIA were competitively antagonize…

medicine.medical_specialtyAdenosineContraction (grammar)Guinea PigsPopulationAction PotentialsStimulationAdenosine-5'-(N-ethylcarboxamide)In Vitro TechniquesMembrane PotentialsAdenosine deaminaseTheophyllineInternal medicinemedicineAnimalseducationPharmacologyMembrane potentialeducation.field_of_studybiologyChemistryCalcium RadioisotopesMyocardiumPurinergic receptorReceptors PurinergicHeartDipyridamoleMyocardial ContractionAdenosineAdenosine receptorElectric StimulationEndocrinologyPhenylisopropyladenosinecardiovascular systembiology.proteinRubidium RadioisotopesResearch Articlemedicine.drugBritish Journal of Pharmacology
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Bilateral buccal space lipoma: A rare case presentation

2019

Background The lipoma of the oral cavity is a relatively rare pathology, characterized by overgrowth of the mature adipocytes. Buccal fat pad lipomas usually interfere with the esthetics and the function of the face. Case Report A sixteen-year-old patient reported slow-growing swelling, which started two years ago. Clinical examination revealed two bilateral masses in the soft tissue. MRI imaging revealed a characteristic image of bilateral lipomas connected to the buccal fat pad. Surgical removal was conducted and the histology report confirmed our clinical diagnosis of common lipoma. Discussion The lipoma of the buccal fat pad is a benign neoplasm of the adipose tissue. It should be remov…

medicine.medical_specialtyAdipose tissuePhysical examinationCase Report03 medical and health sciences0302 clinical medicinestomatognathic systemRare casemedicineotorhinolaryngologic diseases030223 otorhinolaryngologyGeneral DentistryBuccal fat padmedicine.diagnostic_testbusiness.industrySoft tissue030206 dentistryLipomamedicine.disease:CIENCIAS MÉDICAS [UNESCO]3. Good healthSurgerybody regionsstomatognathic diseasesUNESCO::CIENCIAS MÉDICASBuccal spacePresentation (obstetrics)Oral SurgerybusinessJournal of Clinical and Experimental Dentistry
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Digital Rectal Examination (Fig. 2a and 2b)

1979

During examination of the anal region and before doing the rectal examination, the hand is protected by a plastic glove. A number of disposable gloves of varying strengths are on the market. One may additionally use a finger cot on the forefinger, which is removed after the examination. The examination can also be done using a finger cot alone with the finger stuck through a piece of gauze that protects the rest of the hand. Right-handed examiners often elect to use the forefinger of the left hand for the rectal examination and keep the right hand uncontaminated for handling instruments.

medicine.medical_specialtyAnal fissuremedicine.diagnostic_testbusiness.industryAnal RegionRectal examinationAnal canalmedicine.diseaseSurgerybody regionsRectal prolapsemedicine.anatomical_structureFINGER COTInternal HemorrhoidmedicinebusinessRest (music)
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Bone marrow biopsy in Hodgkin's lymphoma

2004

In the study of patients with Hodgkin's lymphoma (HL) the evaluation of bone marrow biopsy (BMB) can be difficult. In this review we analyze the main diagnostic features and the clinical risk factors of BM involvement. Although the role of BMB is criticized by some authors, its value is irreplaceable in the staging of HL and in the diagnosis of primary medullary HL. The Ann Arbor staging committee criteria should be revised and updated in the light of the current immunohistochemical studies that give a fundamental help in the diagnostic process. A single BMB should be adequate for diagnosis in most instances. In cases of suspicious involvement a controlateral BMB could be performed.

medicine.medical_specialtyAnn Arbor stagingmedicine.diagnostic_testMedullary cavitybusiness.industryHematologyGeneral MedicineHodgkin's lymphomamedicine.diseaseLymphomaBone marrow examinationImmunophenotypingmedicine.anatomical_structureBiopsyMedicineRadiologyBone marrowbusinessEuropean Journal of Haematology
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