6533b862fe1ef96bd12c6e96
RESEARCH PRODUCT
State of the Art-High-Sensitivity Troponins in Acute Coronary Syndromes.
Philip WenzelJohannes WildMartin GeyerThomas MünzelTommaso Gorisubject
medicine.medical_specialtyAcute coronary syndromeCardiac biomarkersMyocardial InfarctionPhysical examinationContext (language use)030204 cardiovascular system & hematologySensitivity and SpecificityDiagnosis Differential03 medical and health sciences0302 clinical medicinemedicineHumans030212 general & internal medicineMyocardial infarctionAcute Coronary SyndromeIntensive care medicinebiologymedicine.diagnostic_testMedical treatmentbusiness.industryGeneral Medicinemedicine.diseaseTroponinTroponinbiology.proteinBiomarker (medicine)Cardiology and Cardiovascular MedicinebusinessBiomarkersdescription
In cases of suspected acute coronary syndrome (ACS), rapid and accurate diagnosis is essential to establish effective evidence-based medical treatment. Patients' history, clinical examination, 12-lead electrocardiogram, and cardiac biomarkers are cornerstones in initial management. Since high-sensitivity cardiac troponins were established, they have markedly expedited and revolutionized rule-in and rule-out pathways of patients with ACS and changed our everyday clinical practice. Thus, they have become an indispensable tool in daily routine in emergency units. This review focuses on historical and contemporary standards in laboratory biomarkers of myocardial injury and discusses their implication in the context of the updated universal definition of myocardial infarction.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-10-10 | Cardiology clinics |