Search results for "ample"
showing 10 items of 2398 documents
Surgical treatment vs. conservative treatment in intravenous bisphosphonate-related osteonecrosis of the jaws. Systematic review
2017
AIMS To determine the success rates of the surgical and non-surgical treatments in the management of bisphosphonate-related osteonecrosis of the jaws (BRONJ). MATERIAL AND METHODS A systematic review of the literature was made. A PubMed Medline database search was performed in order to include clinical studies published in English,between2004 and 2014 with the following key-words: "BRONJ AND treatment" and "NOT osteoporosis". The following data was gathered: authors, title, year of publication, aim of study, level of evidence, sample size, treatment performed, treatment outcomes and follow-up. Studies including more than 20 patients with at least 6 months of follow-up, and that specify the …
Influence of Transcranial Direct Current Stimulation on Psychomotor Symptoms in Major Depression
2020
Background: Transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal cortex (dlPFC) might be a promising treatment strategy for depression. As disturbances in psychomotor activity are one of the key features of unipolar depression are, we aimed to evaluate the behavioral effects of ten tDCS sessions over a 5-day period on psychomotor retardation in depressed patients. Methods: Twenty-three treatment-resistant depressed patients received either active or sham anodal tDCS to the left dorsolateral prefrontal cortex (2 mA, 10 sessions over 1 week). Psychomotor functioning was registered by means of observer ratings (Salpê
A pilot study on non-invasive treatment of migraine: The self-myofascial release
2021
The aims of this paper was to determine the effect of self-myofascial release (SMFR) on postural stability and to analyze if it can influence migraine condition. Twenty-five subjects (age 49.7±12.5) affected by migraine were enrolled. Assessments included a stabilometric analysis in order to evaluate balance and plantar support, with eyes open (OE) and closed (CE); cervical ROM measurement; evaluation of upper limb strength through handgrip. All the analysis were carried out before and after the administration of a single SMFR protocol, using medium density small balls laid in the three most painful trigger points in migraine patients: trapezius, sternocleidomastoids and suboccipital muscle…
Instability of misoprostol tablets stored outside the blister: a potential serious concern for clinical outcome in medical abortion.
2014
IntroductionMisoprostol (Cytotec) is recognised to be effective for many gynaecological indications including termination of pregnancy, management of miscarriage and postpartum haemorrhage. Although not licensed for such indications, it has been used for these purposes by millions of women throughout the world. Misoprostol tablets are most often packaged as multiple tablets within an aluminium strip, each within an individual alveolus. When an alveolus is opened, tablets will be exposed to atmospheric conditions.ObjectiveTo compare the pharmaco technical characteristics (weight, friability), water content, misoprostol content and decomposition product content (type A misoprostol, type B mis…
Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence
2019
Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a reference ointment containing calcipotriol and betamethasone (Daivobet 50 µ
Orthogonal switching of AMS axes during type-2 fold interference : Insights from integrated X-ray computed tomography, AMS and 3D petrography
2017
We applied X-ray computed microtomography (μ-CT) in combination with anisotropy of magnetic susceptibility (AMS) analysis to study metamorphic rock fabrics in an oriented drill core sample of pyrite-pyrrhotite-quartz-mica schist. The sample is extracted from the Paleoproterozoic Martimo metasedimentary belt of northern Finland. The μ-CT resolves the spatial distribution, shape and orientation of 25,920 pyrrhotite and 153 pyrite grains localized in mm-thick metapelitic laminae. Together with microstructural analysis, the μ-CT allows us to interpret the prolate symmetry of the AMS ellipsoid and its relationship to the deformation history. AMS of the sample is controlled by pyrrhotite porphyro…
Differentiation among dairy products by combination of fast field cycling NMR relaxometry data and chemometrics
2021
A set of commercial milk and Sicilian cheeses was analysed by a combination of fast field cycling (FFC) nuclear magnetic resonance (NMR) relaxometry and chemometrics. The NMR dispersion (NMRD) curves were successfully analysed with a mathematical model applied on Parmigiano-Reggiano (PR) cheese. Regression parameters were led back to the molecular components of cheeses (water trapped in casein micelles, proteins and fats) and milk samples (water belonging to hydration shells around dispersed colloidal particles of different sizes and bulk water). The application of chemometric analysis on relaxometric data enabled differentiating milk from cheeses and revealing differences within the two sa…
A new approach to calibrate the thermal conditions in space charge measurements on HVDC mini-cables
2019
The PEA method is currently widespread used for space charge measurements in mini-cables in order to qualify the behavior of semicon-dielectric-semicon compound under electric and thermal stress. The main goal of this research is to quantitatively evaluate the relationship between the thermal boundary conditions applied to cables or mini-cables and the maximum local electric field due to the accumulated space charge. Hitherto, several research groups have obtained thermal gradients over the dielectric's radius heating the conductor by Joule effect due to an induced current. In this paper, a numerical approach is offered to calibrate the heat exchange boundary conditions to apply to a sample…
Pokémon GO 2016: Exploring Situational Contexts of Critical Incidents in Augmented Reality
2016
Pokémon GO, an augmented reality mobile game, captured the attention of millions of people around the world in July 2016. Various sources from around the globe have reported both positive and negative incidents and outcomes related to the game. Some of the incidents have been particularly remarkable for the player, i.e., critical incidents. A critical incident is a single experience, which a person perceives or remembers as unusually positive or negative. Critical incidents typically are highly influential for human behaviour, and thus, important to study. Playing augmented reality games can take place in varying situational contexts. Situational context includes information that can be use…
Ecologists overestimate the importance of predictor variables in model averaging: a plea for cautious interpretations.
2014
Abstract: Information-theory procedures are powerful tools for multimodel inference and are now standard methods in ecology. When performing model averaging on a given set of models, the importance of a predictor variable is commonly estimated by summing the weights of models where the variable appears, the so-called sum of weights (SW). However, SWs have received little methodological attention and are frequently misinterpreted. We assessed the reliability of SW by performing model selection and averaging on simulated data sets including variables strongly and weakly correlated to the response variable and a variable unrelated to the response. Our aim was to investigate how useful SWs are …