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RESEARCH PRODUCT

Influence of Transcranial Direct Current Stimulation on Psychomotor Symptoms in Major Depression

Emmanuel HaffenDjamila BennabiJuliana Teti MayerThierry PozzoThierry PozzoAmbra BisioNicolas Carvalho

subject

medicine.medical_specialtymedicine.medical_treatmentStimulationAudiologybehavioral disciplines and activitiesArticle03 medical and health sciences0302 clinical medicinepsychomotor symptomsmedicinePsychomotor learningPsychomotor functionTranscranial direct-current stimulationPsychomotor retardationmajor depressive disorderbusiness.industryGeneral NeuroscienceSmall samplemedicine.diseaseretardation030227 psychiatryMajor depressive disorderAntidepressantmedicine.symptomtranscranial direct current stimulationbusiness030217 neurology & neurosurgery

description

Background: Transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal cortex (dlPFC) might be a promising treatment strategy for depression. As disturbances in psychomotor activity are one of the key features of unipolar depression are, we aimed to evaluate the behavioral effects of ten tDCS sessions over a 5-day period on psychomotor retardation in depressed patients. Methods: Twenty-three treatment-resistant depressed patients received either active or sham anodal tDCS to the left dorsolateral prefrontal cortex (2 mA, 10 sessions over 1 week). Psychomotor functioning was registered by means of observer ratings (Salp&ecirc

10.3390/brainsci10110792http://hdl.handle.net/11567/1028995