Search results for "anterior cruciate ligament"

showing 10 items of 43 documents

Influence of age on osteoarthritis progression after anterior cruciate ligament transection in rats.

2013

Abstract The anterior cruciate ligament transection (ACLT) model of osteoarthritis (OA) in young rats is widely used to study the pathogenesis of OA and possible treatment approaches. As aging is a key factor in the progression of this condition, it is hypothesized that animals may vary in their responses to ACLT according to their age. The histopathological features of young (2 month-old) and middle-aged (12 month-old) rats in the presence or absence of ACLT were compared. The results indicated that moderate degradative changes can be detected in the knee joints of sham-operated middle-aged rats compared with young animals. After ACLT, cartilage degradation was significantly higher in midd…

Cartilage ArticularMalemedicine.medical_specialtyAgingAnterior cruciate ligamentOsteoarthritisBiochemistryCartilage degradationPathogenesisEndocrinologyInternal medicineSynovitisOsteoarthritisGeneticsmedicineAnimalsRats WistarMolecular BiologyCollagen Type IISynovitisbusiness.industryExperimental modelAnterior Cruciate Ligament InjuriesInterleukinCell Biologymedicine.diseaseArthritis ExperimentalSurgeryRatsmedicine.anatomical_structureEndocrinologyDisease ProgressionCytokinesProteoglycansAnalysis of varianceInflammation MediatorsbusinessExperimental gerontology
researchProduct

Regulation of the inflammatory response by tin protoporphyrin IX in the rat anterior cruciate ligament transection model of osteoarthritis

2010

The purpose of this study was to investigate several inflammatory mediators and cartilage degradation molecules as possible biomarkers of joint lesion in the anterior cruciate ligament transection (ACLT) model of osteoarthritis in rats. We also assessed whether the treatment with the anti-inflammatory agent tin protoporphyrin IX (SnPP) reduces the progression of disease. Our results indicate that serum levels of interleukin (IL)-6 and PGE2 are significantly increased in ACLT rats 10 weeks after surgery, whereas the increases in IL-1β and tumor necrosis-α were not significant. In addition, our data suggest that IL-17 is the main pro-inflammatory cytokine in the ACLT joint. We have shown that…

Cartilage ArticularMalemedicine.medical_specialtyMetalloporphyrinsAnterior cruciate ligamentType II collagenProtoporphyrinsInflammationOsteoarthritisDinoprostoneLesionchemistry.chemical_compoundInternal medicineOsteoarthritisHyaluronic acidmedicineAnimalsOrthopedics and Sports MedicineAnterior Cruciate LigamentEnzyme InhibitorsRats WistarCartilage oligomeric matrix proteinbiologybusiness.industryAnterior Cruciate Ligament InjuriesCartilageAnti-Inflammatory Agents Non-Steroidalmedicine.diseaseStifleRatsSurgeryDisease Models AnimalEndocrinologymedicine.anatomical_structurechemistrybiology.proteinCytokinesmedicine.symptombusinessBiomarkersJournal of Orthopaedic Research
researchProduct

A non-linear stochastic approach of ligaments and tendons fractional-order hereditariness

2020

Abstract In this study the non-linear hereditariness of knee tendons and ligaments is framed in the context of stochastic mechanics. Without losing the possibility of generalization, this work was focused on knee Anterior Cruciate Ligament (ACL) and the tendons used in its surgical reconstruction. The proposed constitutive equations of fibrous tissues involves three material parameters for the creep tests and three material parameters for relaxation tests. One-to-one relations among material parameters estimated in creep and relaxations were established and reported in the paper. Data scattering, observed with a novel experimental protocol used to characterize the mechanics of the tissue, w…

GeneralizationQuantitative Biology::Tissues and OrgansAnterior cruciate ligamentPhysics::Medical PhysicsConstitutive equationNon-linear creepAerospace Engineering020101 civil engineeringOcean EngineeringContext (language use)Probability density function02 engineering and technology0201 civil engineeringNon-linear relaxation0203 mechanical engineeringmedicineCivil and Structural EngineeringMathematicsRandom hereditarinessMechanical EngineeringMathematical analysisRelaxation (iterative method)Statistical and Nonlinear Physicsmusculoskeletal systemCondensed Matter PhysicsNon-linear creep; Non-linear relaxation; Random hereditarinessNonlinear system020303 mechanical engineering & transportsmedicine.anatomical_structureNuclear Energy and EngineeringCreep
researchProduct

Unterschiede im Erhaltungszustand zwischen vorderem und hinterem Kreuzband bei rheumatoider Arthritis

2008

In rheumatoid arthritis (RA) we examined the cruciate ligaments of 16 patients by the use of light- and transmission electron microscopy. Considerable differences between the anterior (ACL) and the posterior cruciate ligament (PCL) were observed. The ACL showed dramatic ultrastructural changes, against that the PCL was compact and well conserved. The preservation of PCL in joint surgery can morphologically be recommended. Perhaps the greater inflammatory process on the surface of ACL is responsible for the observed differences.

Joint surgerybusiness.industryAnterior cruciate ligamenttechnology industry and agriculturemacromolecular substancesAnatomyequipment and suppliesmusculoskeletal systemmedicine.diseaseLower limbmedicine.anatomical_structurePosterior cruciate ligamentRheumatoid arthritismedicineOrthopedics and Sports MedicineSurgeryNuclear medicinebusinesshuman activitiesZeitschrift für Orthopädie und ihre Grenzgebiete
researchProduct

MRT des Kniegelenkes: Fehleranalyse bezüglich der Meniskus- und Kreuzbanddiagnostik an einem arthroskopisch kontrollierten Patientenkollektiv

1998

PURPOSE To categorise discrepancies in findings of the menisci and anterior cruciate ligament (ACL) between arthroscopy and MRI. MATERIALS AND METHODS The MRIs of 236 patients were retrospectively analysed by an experienced radiologist without knowledge of clinical and/or operative findings. Discrepancies in arthroscopic findings were reevaluated together with the arthroscopist to determine their cause of error. RESULTS The diagnostic accuracies for injuries of the medial and lateral meniscus and the ACL were 92.4%, 92.4%, and 94.1%, respectively. For the menisci, causes for discrepancies in findings (n = 31) were: overinterpretation of central signal intensities with contact to the menisca…

Lateral meniscusmedicine.diagnostic_testbusiness.industryAnterior cruciate ligamentArthroscopyMeniscus (anatomy)Knee Jointmusculoskeletal systemClinical routineMr imagingmedicine.anatomical_structuremedicineTearsRadiology Nuclear Medicine and imagingbusinessNuclear medicineRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
researchProduct

Niederfeld-MR-Tomographie des Kniegelenkes: Ergebnisse einer prospektiven, arthroskopisch kontrollierten Studie

2008

PURPOSE To define the diagnostic accuracy of an open low-field MR unit (Magnetom Open, Siemens, Erlangen) in traumatic knee lesions. MATERIALS AND METHODS The MRIs of 150 patients were prospectively evaluated by two independent readers with different experience levels. The study protocol included a proton-density weighted SE-sequence in the sagittal, a T2.-weighted Flash-2D-sequence in the coronal, and a 3D-acquisition (DESS) in the axial plane. 75 patients were treated either conservatively or operatively. RESULTS Based on arthroscopy as the gold standard, the sensitivities, specificities, and diagnostic accuracies for lesions of the medial and lateral meniscus, the anterior cruciate ligam…

Lateral meniscusmedicine.medical_specialtymedicine.diagnostic_testbusiness.industryHyaline cartilageAnterior cruciate ligamentArthroscopyMeniscus (anatomy)musculoskeletal systemSurgeryCruciate ligamentmedicine.anatomical_structurePosterior cruciate ligamentmedicineRadiology Nuclear Medicine and imagingNuclear medicinebusinessMedial meniscusRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
researchProduct

Combined Rupture of the Right Anterior Cruciate Ligament and Patellar Tendon on a 28-Year-Old Spanish Professional Handball Player Successfully Treat…

2022

Background: We present a case of combined rupture of the right anterior cruciate ligament (ACL) and patellar tendon (PT) in a 28-year-old professional handball player that was successfully treated by single-stage reconstructive surgery. The combined rupture of the ACL and PT is a rare injury pattern, and there are only a few cases reported in the literature. Presently, little evidence exists to guide management decisions for these patients. In comparison to isolated injuries, the combined rupture of the PT and ACL presents many management dilemmas. Case Report: A professional handball player from the Valencia Handball Club in the Spanish ASOBAL league had a rupture of the PT, ACL, medial co…

MaleAdultRuptureArticulacionsAnterior Cruciate Ligament ReconstructionPatellar LigamentAnterior Cruciate Ligament InjuriesHumansEsports LesionsGeneral MedicineAnterior Cruciate LigamentThe American journal of case reports
researchProduct

Altered hip control during a standing knee-lift test is associated with increased risk of knee injuries

2020

Few prospective studies have investigated hip and pelvic control as a risk factor for lower extremity (LE) injuries. The purpose of this study was to investigate whether deficits in hip and lumbopelvic control during standing knee lift test are associated with increased risk of acute knee and LE injuries in youth team sports. At baseline, 258 basketball and floorball players (aged 12‒21 y.) participated in a standing knee lift test using 3‐dimensional motion analysis. Two trials per leg were recorded from each participant. Peak sagittal plane pelvic tilt and frontal plane pelvic drop/hike were measured. Both continuous and categorical variables were analysed. New non‐contact LE injuries, an…

MalePelvic tilteturistisideLiikuntatiede - Sport and fitness sciencesTeam sportpolvet030204 cardiovascular system & hematology0302 clinical medicineRisk FactorsTask Performance and AnalysisOrthopedics and Sports MedicineProspective StudiesChildProspective cohort studyurheiluvammatLumbar Vertebraeanterior cruciate ligamentBiomechanical Phenomenamedicine.anatomical_structureAthletic InjuriesFemalebiomekaniikkateam sportsmedicine.medical_specialtyAdolescentknee injuriesAnterior cruciate ligamentKirurgia anestesiologia tehohoito radiologia - Surgery anesthesiology intensive care radiologyPhysical Therapy Sports Therapy and RehabilitationKnee InjuriesbiomechanicsPelvisYoung Adult03 medical and health sciencesmedicineHumansjoukkueurheiluRisk factorHipbusiness.industryscreeningkehonhallinta030229 sport sciencesmedicine.diseaseACL injurySagittal planePhysical therapyAnklebusinesshuman activities
researchProduct

Acute injuries in Finnish junior floorball league players

2018

Abstract Objectives To investigate the incidence and characteristics of acute time-loss injuries in Finnish junior floorball league players. Design Prospective cohort study with 3-year follow-up. Methods One hundred and eighty-six female and male players (mean age 16.6 ± 1.4) took part in the follow-up study (2011–2014). The training hours and games were recorded on a team diary. Floorball related acute injuries were registered and verified by a research physician. The injury incidence was expressed as the number of injuries per 1000 h of exposure. Incidence rate was calculated separately for games and practices, and for males and females. Results One hundred and forty-four acute time-loss …

Malemedicine.medical_specialtyrecurrencesprains and strainsAdolescentAnterior cruciate ligamentPhysical Therapy Sports Therapy and RehabilitationKnee InjuriesThighathletic injuries03 medical and health sciences0302 clinical medicineInjury Severity ScoreRisk FactorsSprains and strainsEpidemiologyleg injurymedicineHumansOrthopedics and Sports MedicinejoukkueurheiluAnkle InjuriesProspective StudiesSex Distributionepidemiologiata315Prospective cohort studyFinlandurheiluvammat030222 orthopedicsbusiness.industryIncidence (epidemiology)uusiutuminenta3141030229 sport sciencesmedicine.diseasemedicine.anatomical_structureHockeyAthletic InjuriesLigaments ArticularPhysical therapyInjury Severity ScoreepidemiologyFemaleteam sportsAnklebusinesshuman activities
researchProduct

Avoiding tunnel collisions between fibular collateral ligament and ACL posterolateral bundle reconstruction

2010

PURPOSE: The purpose of this study was to evaluate the risk of tunnel collisions of the fibular collateral ligament (FCL) and posterolateral bundle anterior cruciate ligament (PLB-ACL) tunnels during a combined FCL and double-dundle (DB) ACL reconstruction. METHODS: Thirty-six 4th-generation synthetic femurs (Sawbones, Pacific Research Laboratories, Vashon, WA) were utilized, and two different femur sizes were used. A FCL tunnel and a PLB-ACL tunnel were reamed on each femur. The tunnels of synthetic specimens that did not have a collision were filled with an epoxy resin augmented with BaSO(4) and radiographic evaluation, and Multidetector CT exams of the specimens were performed. RESULTS: …

Models Anatomicmedicine.medical_specialtyKnee JointRadiographyAnterior cruciate ligamentSensitivity and SpecificityCondylemedicineSettore MED/33 - Malattie Apparato LocomotoreHumansOrthopedics and Sports MedicineFemurDouble Bundle anterior cruciate ligament reconstruction Multiple ligament reconstruction fibular collateral ligament reconstruction ACL reconstructionFemurAnterior Cruciate LigamentIntraoperative ComplicationsOrthodonticsbusiness.industryFibular collateral ligamentCollateral LigamentsPlastic Surgery ProceduresCombined Modality TherapyBiomechanical Phenomenamedicine.anatomical_structureFibulaCoronal planeOrthopedic surgerySurgeryTomographybusinessTomography X-Ray Computed
researchProduct