Search results for "aroma"
showing 10 items of 1006 documents
Simultaneous Endo- and Exo-Complex Formation of Pyridine[4]arene Dimer with Neutral and Anionic Guests
2017
The formation of complexes between hexafluorophosphate (PF6−) and tetraisobutyloctahydroxypyridine[4]arene has been thoroughly studied in the gas phase (ESI‐QTOF‐MS, IM‐MS, DFT calculations), in the solid state (X‐ray crystallography), and in chloroform solution (1H, 19F, and DOSY NMR spectroscopy). In all states of matter, simultaneous endo complexation of solvent molecules and exo complexation of a PF6− anion within a pyridine[4]arene dimer was observed. While similar ternary complexes are often observed in the solid state, this is a unique example of such behavior in the gas phase. peerReviewed
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment
2023
Despite the significant outcomes attained by scientific research, breast cancer (BC) still represents the second leading cause of death in women. Estrogen receptor-positive (ER+) BC accounts for the majority of diagnosed BCs, highlighting the disruption of estrogenic signalling as target for first-line treatment. This goal is presently pursued by inhibiting aromatase (AR) enzyme or by modulating Estrogen Receptor (ER) α. An appealing strategy for fighting BC and reducing side effects and resistance issues may lie in the design of multifunctional compounds able to simultaneously target AR and ER. In this paper, previously reported flavonoid-related potent AR inhibitors were suitably modified…
Plant landscape and phytodiversity in the archeological area of Segesta (NW Sicily)
2018
In the system of Sicilian archaeological parks, the area of Segesta - an ancient city of western Sicily referring to the Carthaginian eparchy, - represents, together with Selinunte, Erice and Mothia, another integrated hotspot of biodiversity and archeaology. The current plant landscape is strongly influenced by a millenary anthropic transformation. There are no residual expressions of the original plant covering that, with reference to the environmental potential of the area, can be traced back to the evergreen Mediterranean forest dominated by Quercus ilex, presently only sporadically occurring in the area of the ruins, together with other species related to associations and upper syntaxa…
Risk assessment of exposure to organic chemicals in children and mothers using human biomonitoring
2022
Today, global chemical manufacturing is increasing each year, making environmental pollution and exposure to chemicals a serious public health problem linked to the development of many non-genetic diseases. Approximately, 70 % of chemicals consumed in Europe in 2019 were hazardous for human health. These harmful substances can enter to the food chain and remain in the environment, making humans exposed to them mainly by ingestion, inhalation or dermal exposure. Consequently, exposure to chemicals should be continuously monitored for assuring health protection of citizens by two ways: i) studying their presence in environmental compartments, such as water, food, soil or air, by environmental…
Aqueous-phase reactive species formed by fine particulate matter from remote forests and polluted urban air
2021
In the aqueous phase, fine particulate matter can form reactive species (RS) that influence the aging, properties, and health effects of atmospheric aerosols. In this study, we explore the RS yields of aerosol samples from a remote forest (Hyytiälä, Finland) and polluted urban locations (Mainz, Germany; Beijing, China), and we relate the RS yields to different chemical constituents and reaction mechanisms. Ultra-high-resolution mass spectrometry was used to characterize organic aerosol composition, electron paramagnetic resonance (EPR) spectroscopy with a spin-trapping technique was applied to determine the concentrations of ⚫OH, O2⚫-, and carbon- or oxygen-centered organic radicals, and a …
The formation, properties and impact of secondary organic aerosol: Current and emerging issues
2009
Hallquist, M. Wenger, J. C. Baltensperger, U. Rudich, Y. Simpson, D. Claeys, M. Dommen, J. Donahue, N. M. George, C. Goldstein, A. H. Hamilton, J. F. Herrmann, H. Hoffmann, T. Iinuma, Y. Jang, M. Jenkin, M. E. Jimenez, J. L. Kiendler-Scharr, A. Maenhaut, W. McFiggans, G. Mentel, Th. F. Monod, A. Prevot, A. S. H. Seinfeld, J. H. Surratt, J. D. Szmigielski, R. Wildt, J.; Secondary organic aerosol (SOA) accounts for a significant fraction of ambient tropospheric aerosol and a detailed knowledge of the formation, properties and transformation of SOA is therefore required to evaluate its impact on atmospheric processes, climate and human health. The chemical and physical processes associated wit…
Selective recognition of aromatic hydrocarbons by endo-functionalized molecular tubes via C/N-H⋅⋅⋅π interactions
2018
Molecular recognition of aromatic hydrocarbons by four endo-functionalized molecular tubes has been studied by 1H NMR spectroscopy, computational methods, and single crystal X-ray crystallography. The binding selectivity is rationalized by invoking shape complementarity and dipole alignment. The non-covalent interactions are proved to predominantly be C/N-H⋅⋅⋅π interactions. peerReviewed
Crystal structure and Hirshfeld surface analysis of (2E)-3-(3-bromo-4-fluorophenyl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one
2018
The title compound is constructed from two aromatic rings (3-bromo-4-fluorophenyl and 3,4-dimethoxyphenyl), which are linked by a C=C—C(=O)—C enone bridge and form a dihedral angle of 17.91 (17)°. In the crystal, molecules are linked by C—H⋯O hydrogen bonds enclosing rings of (14) graph-set motif to form layers parallel to (10).
L'initiation fictionnelle dans Le Chiendent et Le vol d'Icare
2010
Effect of gases on biochemical stabilization
2019
International audience; Lipid or protein are sensitive to peroxidation and inert gas limit or stop adulterations. Unsaturated lipids are peroxided by ground state dioxygen in presence of catalysts (iron, enzymes) or after thermal dissociation of C=C bond, and by excited state dioxygen without any assistance (photo-oxidation). Inerting fragile oils by bubbling with dinitrogen or carbon dioxide that are soluble gas in oil slows oxidation process during storage or frying. In a same way, limit the oxidation of the tryptophan residues of protein is possible by reducing oxygen content. Oxidation leads also to oxidation of thiol in disulfide, which induced protein cross-linked and decay of functio…