Search results for "arthritis"

The effects of whole-body vibration training on knee function and physical performance of middle-aged and elderly woman with knee osteoarthritis and …

2014

Effects of whole-body vibration exercise on muscular strength and power, functional mobility and self-reported knee function in middle-aged and older…

2013

Abstract Background Whole-body vibration training using vertical-vibration machines is called “acceleration training” (AT). The purpose of this study was to elucidate the effect of AT on lower-limb muscular strength and power, functional mobility and self-reported knee function in middle-aged and older Japanese women with knee pain. Methods Thirty-eight middle-aged and older Japanese women (aged 50–73 years) with knee pain were divided into two groups: (1) the AT group (n = 29) engaged in AT three times per week for eight weeks, and (2) the control group (C group, n = 9). The AT program consisted of flexibility training, strength training of mainly the quadriceps and surrounding muscles and…

T Cell Large Granular Lymphocytic Leukemia in Association with Sjögren’s Syndrome

2009

T cell large granular lymphocytic (LGL) leukemia is a rare condition accounting for 2–3% of all mature lymphoid leukemias. Here, we present the case of a 73-year-old woman presenting with neutropenia and anemia (hemoglobin 9.9 g/dl). Hematological assessment revealed the presence of a T cell LGL leukemia. At the time of T cell LGL leukemia diagnosis, the patient developed xerophthalmia and xerostomia, and a diagnosis of Sjögren’s syndrome was made following salivary gland biopsy. The finding of large granular lymphocytes in the context of autoimmune disorders is well-known, though it often occurs with rheumatoid arthritis or in association with a positive autoantibody titer in the absence o…

Porphyromonas gingivalis, Periodontal and Systemic Implications: A Systematic Review

2019

In recent scientific literature, oral infections and systemic manifestations, or correlations between oral health and systemic diseases are a topic of discussion. Porphyromonas gingivalis is one of the bacteria implicated in the biofilm formation of bacterial plaque, and plays an important role in the progression of periodontal disease. In this systematic review authors have evaluated the literature of the last 10 years on P. gingivalis and all the systemic implications proven. This study therefore evaluates all the districts of the organism in which this bacterium may have implications. From the results it emerges that P. gingivalis has implications in the onset of different systemic patho…

"Being Flexible": graduates Facing Changes in Their Work Environment

2011

According to the crucial importance of innovation for modern economies, the role of graduates regarding innovation appears to be a major topic when their performances in the labour market at stake. Five main questions are addressed in this chapter: (1) What does innovation mean? (2) Which organisations are likely to be more innovative? (3) What role do Higher Education graduates play regarding innovation? (4) Are they equipped to do develop innovation? (5) Which are the occupations more related to innovation, and are innovative activities rewarded? The results presented in this chapter confirm that higher education graduates are crucial actors in the innovation process. The jobs of innovati…

Robotic total knee arthroplastyThe accuracy of CT-based component placement

2004

Accurate alignment of the components in total knee arthroplasty is important. By use of postoperative CT controls, we studied the ability of a robotic effector to accurately place and align total knee arthroplasty (TKA) components according to a purely CT-based preoperative plan.Robotic TKA was performed in 13 patients (6 men) with primary gonarthrosis. Locator screws were placed into femur and tibia under spinal anesthesia. A CT-scan including the femoral head, knee and ankle was performed. In the preoperative planning software, virtual components were positioned into the CT volume. In a second operation, the robot milled femur and tibia with a high-speed milling tool according to the preo…

Isolated laryngeal leishmaniasis in a 55-year-old man with dysphonia and rheumatoid arthritis: Case report and literature review

2013

Visceral adiposity in patients with psoriatic arthritis and psoriasis alone and its relationship with metabolic and cardiovascular risk

2020

Abstract Background Fat mass distribution, especially in the abdominal visceral region, has been rarely evaluated in patients with PsA or psoriasis (PsO). Methods Patients with PsA and patients with PsO alone were evaluated and compared with control subjects (1:1 ratio in each patient group) matched for age, sex and BMI category. Body composition and fat distribution (android and visceral fat) were evaluated by DXA. Anthropometric measurements, disease activity and the systematic coronary risk evaluation (SCORE) cardiovascular risk were assessed. Metabolic parameters (insulin, homeostasis model assessment for insulin resistance), serum adipokines [total and high-molecular-weight adiponectin…

A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats

2003

AbstractThe synthetic chalcone derivative 1-(2,4-dichlorophenyl)-3-(3-(6,7-dimethoxy-2-chloroquinolinyl))-2-propen-1-one (CIDQ) was evaluated for its anti-inflammatory, analgesic and immunomodulatory efficacy in-vitro and in-vivo. CIDQ concentration-dependently inhibited the production of nitric oxide (NO) (IC50 4.3 μM) and prostaglandin E2 (PGE2) (IC50 1.8 μM) in RAW 264.7 macrophages stimulated with lipopolysaccharide. Human mononuclear cell proliferation was significantly inhibited by 10 μM CIDQ. Oral administration of CIDQ (10–30 mg kg−1) in the 24-h zymosan-stimulated mouse air-pouch model produced a dose-dependent reduction of cell migration as well as NO and PGE2 levels in exudates. …

ttCH, a selective inhibitor of inducible nitric oxide synthase expression with antiarthritic properties

2003

In a previous work, we investigated the effects of a series of dimethoxy- and trimethoxychalcone derivatives, with various patterns of fluorination, on nitric oxide production in lipopolysaccharide-stimulated murine RAW 264.7 cells. The present study was designed to determine if 2,4,6-trimethoxy-2'-trifluoromethylchalcone (ttCH) could modulate the production of nitric oxide (NO) and/or prostaglandins in vitro and in vivo. On the mouse macrophage cell line RAW 264.7, ttCH inhibited dose-dependently NO and prostaglandin E(2) production, with IC(50) in the micromolar range. This compound had no direct inhibitory effect on inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 activities. …