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RESEARCH PRODUCT

Porphyromonas gingivalis, Periodontal and Systemic Implications: A Systematic Review

Rodolfo MauceriTolga Fikret TözümMichele GaetaLuigi LainoCesare D’amicoLuca FiorilloMarco CicciùGabriele Cervino

subject

LPSOral healthbrain diseasesArthritisBacteremiaReviewOral healthPorphyromonas gingivaliNeurodegenerative disease03 medical and health sciences0302 clinical medicinePeriodontal diseasemedicineneurodegenerative diseasesperiodontitisGeneral DentistryPorphyromonas gingivalisOrganismBrain disease030304 developmental biologyPeriodontitis0303 health sciencesbiologybusiness.industryPeriodontiti030206 dentistryCardiovascular diseasemedicine.diseasebiology.organism_classificationcardiovascular diseasesarthritisRheumatoid arthritisImmunologybusinessPorphyromonas gingivalisArthriti

description

In recent scientific literature, oral infections and systemic manifestations, or correlations between oral health and systemic diseases are a topic of discussion. Porphyromonas gingivalis is one of the bacteria implicated in the biofilm formation of bacterial plaque, and plays an important role in the progression of periodontal disease. In this systematic review authors have evaluated the literature of the last 10 years on P. gingivalis and all the systemic implications proven. This study therefore evaluates all the districts of the organism in which this bacterium may have implications. From the results it emerges that P. gingivalis has implications in the onset of different systemic pathologies, including rheumatoid arthritis, cardiovascular pathologies, and neurodegenerative pathologies. Surely, understanding the mechanisms of diffusion of this bacterium, it would be possible to prevent a series of pathologies. Thus, putting the dentist clinician at the center of prevention for these diseases.

https://doi.org/10.3390/dj7040114