Search results for "article"

showing 10 items of 29275 documents

Design, synthesis and structure-activity relationship of 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of t…

2009

The biological importance of microtubules in mitosis and cell division makes them an interesting target for the development of anticancer agents. Small molecules such as benzo[b]furans are attractive as inhibitors of tubulin polymerization. Thus, a new class of inhibitors of tubulin polymerization based on the 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]furan molecular skeleton, with electron-donating (Me, OMe or OH) or electron-withdrawing (F, Cl and Br) substituents on the benzene ring, was synthesized and evaluated for antiproliferative activity, inhibition of tubulin polymerization and cell cycle effects. Adding a methyl group at the C-3 position resulted in increased activity. The most prom…

structure-activityStereochemistryClinical BiochemistryPharmaceutical ScienceAntineoplastic Agentsmacromolecular substancesBiochemistryChemical synthesisArticleStructure-Activity Relationshipchemistry.chemical_compoundbenzo[b]furansMicrotubuleCell Line TumorFuranDrug DiscoveryHumansStructure–activity relationshipMolecular BiologyBenzofuransCell ProliferationBinding SitesDose-Response Relationship DrugbiologyChemistryTubulin ModulatorsCell growthCell CycleOrganic ChemistrySmall moleculeTubulin Modulatorstubulin polymerizationTubulinDrug Designbiology.proteinMolecular MedicineProtein MultimerizationColchicine
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The power of assessment: What (dis)empowers students in their EFL assessment in a Finnish upper secondary school?

2017

Assessment wields a great deal of power over students. Yet, there is little research on how students, either in general or as individuals, experience assessment. Therefore, this study aimed to explore what disempowers or empowers students in EFL assessment. A total of 146 students from one Finnish upper secondary school answered a questionnaire on assessment and feedback in their EFL studies. The study utilises mixed methods: primarily, the questionnaire data was analysed quantitatively (principal component analysis, step-wise regression analysis), secondarily, qualitative data and analysis were also used. The analyses showed that students reacted to assessment in highly individual ways. Wh…

students’ experiencesupper secondary educationassessmentAssessment Empowerment Disempowerment Students' experiences Upper secondary educationEFLeducationvoimaantuminendisempowermentArticleApples - Journal of Applied Language Studies
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Association between Anxiety, Quality of Life and Academic Performance of the Final-Year-Students in Latvia

2021

The main objective of this study was to investigate the association between final-year students’ anxiety level and quality of life (QOL) with their academic achievements. A longitudinal study was performed in regular schools and in high-rated gymnasiums at the beginning and at the end of the school year. Multiple linear regression models were built for the association between level of anxiety/QOL with academic achievements. Type of school and gender—but not the level of anxiety—were the main predictors of academic achievements of 287 adolescents (e.g., for mathematics, the effect estimates were: β = −1.71 [95% confidence interval −2.21

students’ quality of life050103 clinical psychologyLongitudinal studyAdolescentHealth Toxicology and MutagenesiseducationAnxietylevel of anxietyArticleQuality of lifeAcademic PerformanceLinear regressionmedicineHumans0501 psychology and cognitive sciencesLongitudinal StudiesStudentsAssociation (psychology)Anxiety levelSchools05 social sciencesPublic Health Environmental and Occupational HealthRhigh-rated schoolsLatviaConfidence intervalgender differencesQuality of LifeAnxietyMedicineFemalemedicine.symptom050104 developmental & child psychologyClinical psychologyInternational Journal of Environmental Research and Public Health
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Zabieg medycyny estetycznej w przypadku małoletniego dziecka bez zgody sądu rodzinnego a odpowiedzialność prawnokarna

2017

This article refers to criminal liability for performing aesthetic medicine treatment in a form of plastic surgery without patient’s consent, substitute consent (including collective) or substitute consent of Family Court. Article presents the current state of law in this respect and the correlation between applicable regulations of various branches of law and lex generalis regulations that deal with this issue, i.e. aesthetic medicine treatment.The author evaluates and describes the legal issues related with aesthetic medicine, including the patient’s consent, extended disclosure obligation as well as the ground for statutory liability for committing a prohibited act that is described and …

substitute consent of Family Courtbody deformitiescollective consentextended disclosure obligationconsent of substitute legal representativedeliberate action in the immediate or possible intentionlegality of medical activityperpetratorformal off ence prosecuted on requestcomfort of lifeindividual subject protectionArticle 192 of the Penal Codeconsent of the patientfl aws of declaration of willmedical treatmentaesthetic remedial medicine treatment
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In situ measurements of background aerosol and subvisible cirrus in the tropical tropopause region

2002

[1] In situ aerosol measurements were performed in the Indian Ocean Intertropical Convergence Zone (ITCZ) region during the Airborne Polar Experiment-Third European Stratospheric Experiment on Ozone (APE-THESEO) field campaign based in Mahe, Seychelles between 24 February and 6 March 1999. These are measurements of particle size distributions with a laser optical particle counter of the Forward Scattering Spectrometer Probe (FSSP)-300 type operated on the Russian M-55 high-altitude research aircraft Geophysica in the tropical upper troposphere and lower stratosphere up to altitudes of 21 km. On 24 and 27 February 1999, ultrathin layers of cirrus clouds were penetrated by Geophysica directly…

subvisualAtmospheric ScienceParticle numberMeteorologyaerosolsubvisible cirrusSoil SciencecirrusAquatic ScienceOceanographyAtmospheric sciencestropicsTroposphereGeochemistry and Petrologytropopauseddc:550Earth and Planetary Sciences (miscellaneous)StratosphereEarth-Surface ProcessesWater Science and TechnologyEcologybackgroundPaleontologyForestryJAerosolGeophysicsLidarSpace and Planetary ScienceEnvironmental scienceCirrusTropopauseParticle counterJournal of Geophysical Research: Atmospheres
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Titanocene Selenide Sulfides Revisited: Formation, Stabilities, and NMR Spectroscopic Properties

2019

[TiCp2S5] (phase A), [TiCp2Se5] (phase F), and five solid solutions of mixed titanocene selenide sulfides [TiCp2SexS5−x] (Cp = C5H5−) with the initial Se:S ranging from 1:4 to 4:1 (phases B–E) were prepared by reduction of elemental sulfur or selenium or their mixtures by lithium triethylhydridoborate in thf followed by the treatment with titanocene dichloride [TiCp2Cl2]. Their 77Se and 13C NMR spectra were recorded from the CS2 solution. The definite assignment of the 77Se NMR spectra was based on the PBE0/def2-TZVPP calculations of the 77Se chemical shifts and is supported by 13C NMR spectra of the samples. The following complexes in varying ratios were identified in the CS2 solutions of …

sulfidit77Se-NMR spectroscopyPharmaceutical ScienceCrystal structureSulfidesorganometalliyhdisteet010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Seleniumcrystal structureschemistry.chemical_compoundChalcogenlcsh:Organic chemistrytitanocene selenide sulfidesSelenide0103 physical sciencesDrug DiscoveryOrganometallic CompoundsCarbon-13 Magnetic Resonance SpectroscopyNMR-spektroskopiaPhysical and Theoretical Chemistryta116DLPNO-CCSD(T) calculations13C-NMR spectroscopyCrystallographyMolecular Structure010304 chemical physics<sup>13</sup>C-NMR spectroscopyChemistryChemical shiftOrganic ChemistryTitanocene dichlorideCarbon-13 NMRkiteetStandard enthalpy of formation0104 chemical sciencesNMR spectra databasetitaani<sup>77</sup>Se-NMR spectroscopyChemistry (miscellaneous)Carbon DisulfideseleeniQuantum TheoryMolecular MedicinePhysical chemistryMolecules
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Tuning of Emission Wavelength of CaS:Eu by Addition of Oxygen Using Atomic Layer Deposition

2021

| openaire: EC/H2020/820423/EU//S2QUIP | openaire: EC/H2020/834742/EU//ATOP | openaire: EC/H2020/965124/EU//FEMTOCHIP Atomic layer deposition (ALD) technology has unlocked new ways of manipulating the growth of inorganic materials. The fine control at the atomic level allowed by ALD technology creates the perfect conditions for the inclusion of new cationic or anionic elements of the already-known materials. Consequently, novel material characteristics may arise with new functions for applications. This is especially relevant for inorganic luminescent materials where slight changes in the vicinity of the luminescent centers may originate new emission properties. Here, we studied the lumines…

sulfiditkalsiumTechnologyMicroscopyQC120-168.85Eu [CaS]TQH201-278.5CaS:Eu; phosphor; photoluminescence; atomic layer depositionatomikerroskasvatusharvinaiset maametallitEngineering (General). Civil engineering (General)ArticlephosphorTK1-9971Descriptive and experimental mechanicsatomic layer depositionCaS:EuphotoluminescenceElectrical engineering. Electronics. Nuclear engineeringohutkalvotTA1-2040fotoluminesenssifosforiMaterials
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Parasite avoidance behaviours in aquatic environments

2018

Parasites, including macroparasites, protists, fungi, bacteria and viruses, can impose a heavy burden upon host animals. However, hosts are not without defences. One aspect of host defence, behavioural avoidance, has been studied in the terrestrial realm for over 50 years, but was first reported from the aquatic environment approximately 20 years ago. Evidence has mounted on the importance of parasite avoidance behaviours and it is increasingly apparent that there are core similarities in the function and benefit of this defence mechanism between terrestrial and aquatic systems. However, there are also stark differences driven by the unique biotic and abiotic characteristics of terrestrial …

suojautuminen0106 biological sciences0301 basic medicineAquatic Organismsbehavioural immunityZoologyinfektioteläinten käyttäytyminen010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyHost-Parasite Interactions03 medical and health sciencesloisetAvoidance LearningAnimalsParasite hostingfreshwaterPathogenvesieläimistöbiologyHost (biology)Aquatic ecosystemfungimarineArticlesHost defencebiology.organism_classificationBiological EvolutionInvertebratesinfectionavoidance behaviourtaudinaiheuttajat030104 developmental biologyAvoidance behaviourVertebratesta1181MacroparasiteGeneral Agricultural and Biological SciencesBacteriapathogenPhilosophical Transactions of the Royal Society B: Biological Sciences
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Coronavirus-related health literacy and perceived restrictiveness of protective measures among community-dwelling older persons in Finland

2021

Abstract Background Older people with limited health literacy may encounter difficulties in finding relevant information on COVID-19, understanding its relevance, and complying with recommended protective measures. Complying with such recommendations has required older as well as younger persons to change their daily lives in ways that have reduced their opportunities for engaging in many activities meaningful to them. Aims To find out from what sources older people have obtained information on protective measures, the level of their coronavirus-related health literacy (CHL), and whether CHL is associated with their perceptions of the restrictiveness of coronavirus-related protective measur…

suojautuminenMaleAgingCross-sectional studyhealth promotiongerontologymedia_common.quotation_subjectvanhukset030209 endocrinology & metabolismHealth literacyterveysosaaminenOdds03 medical and health sciences0302 clinical medicineEnvironmental healthPerceptiontartuntatauditSurveys and QuestionnairesparticipationHumans030212 general & internal medicineAssociation (psychology)RestrictivenessFinlandmedia_commonAgedtiedonlähteetAged 80 and overSARS-CoV-2agingParticipationCOVID-193. Good healthHealth LiteracyHealth promotionCross-Sectional StudiesterveyskäyttäytyminenHealth promotionOriginal ArticleFemaleIndependent LivingGeriatrics and GerontologyPsychologygerontologiaGerontologyIndependent livingikääntyneetAging Clinical and Experimental Research
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The giant panda is cryptic

2021

The giant panda (Ailuropoda melanoleuca) is an iconic mammal, but the function of its black-and-white coloration is mysterious. Using photographs of giant pandas taken in the wild and state-of-the-art image analysis, we confirm the counterintuitive hypothesis that their coloration provides camouflage in their natural environment. The black fur blends into dark shades and tree trunks, whereas white fur matches foliage and snow when present, and intermediate pelage tones match rocks and ground. At longer viewing distances giant pandas show high edge disruption that breaks up their outline, and up close they rely more on background matching. The results are consistent across acuity-corrected c…

suojaväriMammalsEcologygenetic structuresEvolutionBehavioural ecologyisopandaBiological MimicryScienceQRBiological EvolutionArticlePhenotypePhysical Appearance BodyAnimalsHumansMedicineUrsidaeScientific Reports
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