Search results for "asma"

showing 10 items of 4204 documents

Establishment of Polycomb silencing requires a transient interaction between PC and ESC

2001

Two distinct types of Polycomb complexes have been identified in flies and in vertebrates, one containing ESC and one containing PC. Using LexA fusions, we show that PC and ESC can establish silencing of a reporter gene but that each requires the presence of the other. In early embryonic extracts, we find PC transiently associated with ESC in a complex that includes EZ, PHO, PH, GAGA, and RPD3 but not PSC. In older embryos, PC is found in a complex including PH, PSC, GAGA, and RPD3, whereas ESC is in a separate complex including EZ, PHO, and RPD3.

Polycomb-Group ProteinsRepressorSettore BIO/11 - Biologia MolecolarePlasma protein bindingBiologyPolycomb silencingResearch CommunicationGeneticsPolycomb-group proteinsAnimalsDrosophila ProteinsGene silencingGene Silencingreproductive and urinary physiologyPolycomb Repressive Complex 1Reporter geneurogenital systemPolycomb Repressive Complex 2PcG complexEmbryoHistone-Lysine N-MethyltransferasePrecipitin TestsEmbryonic stem cellMolecular biologyRepressor Proteinsembryonic structuresInsect ProteinsDrosophilaRepressor lexAbiological phenomena cell phenomena and immunityESC/PHOProtein BindingDevelopmental BiologyGenes & Development
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The apparently anomalous effects of surfactants on interfacial tension in the IBA/water system near its upper critical solution temperature

2016

We studied the effect of anionic, cationic, and nonionic surfactants on the interfacial tension between the two phases of the isobutyric acid/water system using spinning drop tensiometry. It has been found that interfacial tension decreases with increasing concentration of the surfactant in the case of sodium dodecyl sulfate (SDS) and of dodecyltrimethylammonium chloride (DTAC). However, in the case of Triton X-100 an increase of surfactant concentration leads to an increase of the interfacial tension. Such results are consistent with the upper critical solution temperature (UCST) in the presence of these surfactants: the UCST decreases with increasing SDS and DTAC concentrations while it i…

Polymers and Plastics02 engineering and technology01 natural sciencesSpinning drop tensiometry010305 fluids & plasmasIsobutyric acidSurface tensionchemistry.chemical_compoundColloid and Surface ChemistryPulmonary surfactantUpper critical solution temperature0103 physical sciencesPolymer chemistryMaterials ChemistryMoleculePhysical and Theoretical ChemistrySodium dodecyl sulfateSettore CHIM/02 - Chimica FisicaChemistryDrop (liquid)Cationic polymerizationUpper critical solution temperature (UCST)021001 nanoscience & nanotechnologyChemical engineering0210 nano-technologyInterfacial tensionColloid and Polymer Science
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Tamoxifen-loaded polymeric micelles: preparation, physico-chemical characterization and in vitro evaluation studies.

2004

Several samples of polymeric micelles, formed by amphiphilic derivatives of PHEA, obtained by grafting into polymeric backbone of PEGs and/or hexadecylamine groups (PHEA-PEG-C(16) and PHEA-C(16)) and containing different amount of Tamoxifen, were prepared. All Tamoxifen-loaded polymeric micelles showed to increase drug water solubility. TEM studies provided evidence of the formation of supramolecular core/shell architectures containing drug, in the nanoscopic range and with spherical shape. Samples with different amount of encapsulated Tamoxifen were subjected to in vitro cytotoxic studies in order to evaluate the effect of Tamoxifen micellization on cell growth inhibition. All samples of T…

Polymers and PlasticsAntineoplastic Agents HormonalPolymersSupramolecular chemistryBioengineeringMicellePolyethylene GlycolsBiomaterialsPlasmaDrug Delivery SystemsTamoxifen polymeric micelles polyaspartammideAmphiphileMaterials ChemistryOrganic chemistryHumansMicellesAqueous solutionMolecular StructureChemistryHydrogen-Ion ConcentrationTamoxifenMembraneSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoDrug deliveryLiberationDrug carrierPeptidesBiotechnologyNuclear chemistryMacromolecular bioscience
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Effect of Core-Crosslinking on Protein Corona Formation on Polymeric Micelles.

2021

Most nanomaterials acquire a protein corona upon contact with biological fluids. The magnitude of this effect is strongly dependent both on surface and structure of the nanoparticle. To define the contribution of the internal nanoparticle structure, protein corona formation of block copolymer micelles with poly(N-2-hydroxypropylmethacrylamide) (pHPMA) as hydrophilic shell, which are crosslinked-or not-in the hydrophobic core is comparatively analyzed. Both types of micelles are incubated with human blood plasma and separated by asymmetrical flow field-flow fractionation (AF4). Their size is determined by dynamic light scattering and proteins within the micellar fraction are characterized by…

Polymers and PlasticsChemical PhenomenaLightPolymersNanoparticleBioengineeringProtein Corona02 engineering and technology010402 general chemistry01 natural sciencesMicelleMass SpectrometryPolyethylene GlycolsBiomaterialsCorona (optical phenomenon)PlasmaDynamic light scatteringMaterials ChemistryCopolymerHumansScattering RadiationChromatography High Pressure LiquidMicellesGel electrophoresisChemistry021001 nanoscience & nanotechnologyBlood proteins0104 chemical sciencesNanostructuresCross-Linking ReagentsBiophysicsProtein CoronaAdsorption0210 nano-technologyHydrophobic and Hydrophilic InteractionsBiotechnologyMacromolecular bioscience
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Study of the High-Frequency Inductive Coupled Discharge Plasma Interaction with Walls

2007

The high-frequency electrodeless light sources (HFELS) are widely used as bright radiators of narrow and intense spectral lines covering the region from VUV to IR. Special HFELS filled with pure helium at pressures from 0.2 to 5 Torr were prepared for diagnostics of interaction between the filling element and the wall material (glass). Pollution of the discharge plasma with the oxygen admixture was studied by spectroscopy. Atomic force microscopy experiments were performed to find modification of the wall surface at the nanoscale level. Release of oxygen by the walls is found to depend strongly on the discharge conditions and significant changes of the surface structure are detected after p…

Polymers and PlasticschemistryTorrSurface modificationchemistry.chemical_elementPlasmaAtomic physicsCondensed Matter PhysicsSpectroscopyNanoscopic scaleOxygenHeliumSpectral linePlasma Processes and Polymers
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Continuous-Variable Instantaneous Quantum Computing is Hard to Sample

2017

Instantaneous quantum computing is a sub-universal quantum complexity class, whose circuits have proven to be hard to simulate classically in the Discrete-Variable (DV) realm. We extend this proof to the Continuous-Variable (CV) domain by using squeezed states and homodyne detection, and by exploring the properties of post-selected circuits. In order to treat post-selection in CVs we consider finitely-resolved homodyne detectors, corresponding to a realistic scheme based on discrete probability distributions of the measurement outcomes. The unavoidable errors stemming from the use of finitely squeezed states are suppressed through a qubit-into-oscillator GKP encoding of quantum information,…

PolynomialMathematical optimizationComputer scienceFOS: Physical sciencesGeneral Physics and Astronomy01 natural sciences010305 fluids & plasmas010309 opticsContinuous variableHomodyne detection[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph]Quantum mechanics0103 physical sciencesComplexity classQuantum phase estimation algorithmStatistical physicsQuantum information010306 general physicsQuantumQuantum computerPhysicsQuantum PhysicsQuantum PhysicsSample (graphics)PostselectionProbability distributionQuantum Physics (quant-ph)Physical Review Letters
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Optical diagnostic of temperature in rocket engines by coherent Raman techniques

2004

Abstract This article reviews the study of Raman line shapes of molecular species involved in reactive media, such flames or engines, at high temperature and high pressure. This study is of interest from a fundamental as well as from a practical point of view with regards to the CARS temperature diagnostic of GH2–LOX combustion systems. We will particularly draw attention to recent investigations by means of Stimulated Raman Spectroscopy (SRS) in H2–H2O mixtures at temperature up to 1800 K. Whereas H2–X systems usually exhibit large inhomogeneous effects, due to the speed dependence of the collisional parameters, the absence of such apparent inhomogeneous signatures in the H2–H2O system all…

Polynomialline shapebusiness.product_categoryMaterials scienceEnergy Engineering and Power TechnologydiagnosticCombustion01 natural sciences7. Clean energyTemperature measurement010305 fluids & plasmassymbols.namesakeOptics0103 physical sciences010306 general physicsSpectroscopy[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics][ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]business.industryGeneral EngineeringSpectral line shapeComputational physicsRocketHigh pressureRaman spectroscopysymbolsbusinessRaman spectroscopycollisioncombustion
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Light-induced anomalous Hall effect in massless Dirac fermion systems and topological insulators with dissipation

2019

Employing the quantum Liouville equation with phenomenological dissipation, we investigate the transport properties of massless and massive Dirac fermion systems that mimics graphene and topological insulators, respectively. The massless Dirac fermion system does not show an intrinsic Hall effect, but it shows a Hall current under the presence of circularly-polarized laser fields as a nature of a optically-driven nonequilibrium state. Based on the microscopic analysis, we find that the light-induced Hall effect mainly originates from the imbalance of photocarrier distribution in momentum space although the emergent Floquet–Berry curvature also has a non-zero contribution. We further compute…

PopulationFOS: Physical sciencesGeneral Physics and AstronomyPosition and momentum spaceanomalous Hall effect01 natural sciencesSettore FIS/03 - Fisica Della Materia010305 fluids & plasmaslaw.inventionsymbols.namesakeHall effectlawMesoscale and Nanoscale Physics (cond-mat.mes-hall)0103 physical sciences010306 general physicseducationQuantumPhysicseducation.field_of_studyCondensed Matter - Mesoscale and Nanoscale PhysicsCondensed matter physicsGrapheneFloquet statesopen quantum systemsMassless particleDirac fermionTopological insulatorsymbolsPhysics - OpticsOptics (physics.optics)
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Feasibility of D-D start-up under realistic technological assumptions for EU-DEMO

2021

Abstract One of the main issues in view of the realization of a DEMOnstration fusion reactor is the availability of a sufficient external supply of tritium (T) to start operation. T is an unstable nuclide, which is almost absent in nature and is currently available as by-product in e.g. CANDU, whose operation in the next decades (both in terms of life extension of existing reactors and construction of new ones) is at the moment under debate. During DEMO operation, T will be generated on-site by breeding blanket, employing the neutrons originating from D-T reaction. However, it is considered that a certain initial amount of T is needed to start operation, the so-called start-up inventory. An…

Power stationComputer scienceMechanical EngineeringNuclear engineeringFusion powerBlanketStart up7. Clean energy01 natural sciences010305 fluids & plasmasMoment (mathematics)Nuclear Energy and Engineering0103 physical sciencesGeneral Materials ScienceNuclide010306 general physicsRealization (systems)Order of magnitudeCivil and Structural EngineeringFusion Engineering and Design
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Structural verification and manufacturing procedures of the cooling system, for DEMO divertor target (OVT)

2019

The paper presents the design activities and testing plan of a vertical target mock-up, developed within the pre-conceptual design phase for DEMO Work Package DIV-1 “Divertor Cassette Design and Integration” - EUROfusion Power Plant Physics & Technology (PPPT) program. Activities concerning the Divertor Outboard Vertical Target cooling mock-up are presented in term of CAD model, thermal-hydraulic numerical simulation, structural analysis, structural integrity verification and manufacturing procedure. Moreover, the mechanical dimensions of support systems for Plasma Facing Components (PFCs), manifold and diffuser have been analyzed in detail, in order to avoid structural fault during the tes…

Power stationComputer simulationDesign activitiesDivertor target cooling mock-upNuclear engineeringDivertorMechanical EngineeringDivertor cassetteCADFault (power engineering)01 natural sciences010305 fluids & plasmasNuclear Energy and Engineering0103 physical sciencesWater coolingDEMO; Divertor cassette; Divertor target cooling mock-up; Civil and Structural Engineering; Nuclear Energy and Engineering; Materials Science (all); Mechanical EngineeringGeneral Materials ScienceMaterials Science (all)Test plan010306 general physicsDEMO; Divertor cassette; Divertor target cooling mock-upDEMOSettore ING-IND/19 - Impianti NucleariCivil and Structural Engineering
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