Search results for "asma"
showing 10 items of 4204 documents
Structural assessment of the EU-DEMO WCLL Central Outboard Blanket segment under normal and off-normal operating conditions
2021
Abstract Within the framework of the EUROfusion design activities concerning the EU-DEMO Breeding Blanket (BB) system, a research campaign has been carried out at the University of Palermo with the aim of investigating the structural behaviour of the DEMO Water-Cooled Lithium Lead (WCLL) Central Outboard Blanket (COB) segment. The assessment has been performed considering three different loading scenarios: the Normal Operation (NO), the Over-Pressurization (OP) and the Upward Vertical Displacement Event (VDE-up). In particular, NO scenario represents the loading case referring to the nominal operating conditions, whereas the OP scenario refers to the loading conditions due to an in-box LOCA…
Efecto del polimorfismo de la apolipoproteína E en el perfil lipoproteico y riesgo cardiovascular en una población mediterránea
2002
Fundamento La asociacion de las variantes comunes del gen de la apolipoproteina E (apo E)con arteriosclerosis varia segun las poblaciones. Nuestro objetivo fue estimar la asociacion entreestas variantes geneticas (alelos e2, e3 y e4) con las concentraciones de lipidos plasmaticosy el riesgo de enfermedad cardiovascular (ECV) en una poblacion mediterranea espanola. Pacientes y metodo Se ha realizado un estudio transversal en 486 individuos (144 varones y342 mujeres) procedentes de poblacion general mediterranea (7-85 anos). Se determino el genotipode la apo E y variables antropometricas, bioquimicas y del estilo de vida. Resultados La frecuencia alelica para e2 y e4 fue baja (0,052; interval…
Pharmacokinetics and pharmacodynamics of hydroxyethyl starch in hypovolemic pigs; a comparison of peripheral and intraosseous infusion.
1999
Intraosseous (i.o.) infusion is considered a useful technique for the administration of medications and fluids in emergency situations when peripheral intravascular access is not possible. This study investigated the effectiveness of i.o. versus intravenous (i.v.) infusion of hydroxyethyl starch (HES 200/0.5) in hypovolemic pigs. Twenty-three pigs (8- to 9-week-old) were anaesthesized, instrumented and blood was withdrawn (25-30 ml/kg) to50 mmHg mean arterial pressure (MAP). The animals were left untreated in haemorrhage for 30 min. Relevant haemodynamic parameters were monitored and blood samples were collected for blood gas and HES concentration analysis. Infusion of HES via i.v. or i.o. …
Morphological similarities between DBM and an economic geography model of city growth
2009
International audience; An urban microeconomic model of households evolving in a 2Dcellular automata allows to simulate the growth of a metropolitan area whereland is devoted to housing, road network and agricultural/green areas. Thissystem is self-organised: based on individualistic decisions of economic agentswho compete on the land market, the model generates a metropolitan area withhouses, roads, and agriculture. Several simulation are performed. The resultsshow strong similarities with physical Dieletric breackdown models (DBM). Inparticular, phase transitions in the urban morphology occur when a controlparameter reaches critical values. Population density in our model and theelectric …
Oral manifestations and dental management of patient with leukocyte alterations
2011
Leukocytes are the main cellular elements of inflammatory and immune reactions of the organism. Leukocyte alterations are the consequence of an imbalance between the formation of leukocytes in the bone marrow and its elimination by the mononuclear phagocytic system. Factors that can modify leukopoyesis are varied and can lead to an alteration in the number of leukocytes or tumoral alterations of white cells (leukemias, lymphomas and plasma cell tumors). There is also a wide range of clinical manifestations that can derive from them: from very slight symptoms to life-threatening conditions. In some cases oral manifestations will be the first signs and it will be the dentist’s responsibility …
Bone Healing with or without Platelet-Rich Plasma around Four Different Dental Implant Surfaces in Beagle Dogs
2013
Purpose Surface development is one of the major aims in dental implant engineering. Additive application of substances could possibly improve the new bone formation around dental implants. The present study evaluated the bone reaction on four different implant surfaces with or without platelet-rich plasma (PRP). Materials and Methods Four self-tapping titanium screw implants (Branemark MK III [Nobel Biocare, Goteborg, Sweden], Osseotite [3i, Miami, FL, USA], Xive [Densply Friadent, Mannheim, Germany], and Compress [IGfZ eG, Diez, Germany]) with different surfaces were inserted in each hemimandible of 12 female beagle dogs; the implant positions and the application of PRP were randomized. Af…
Plasma cytokine profiles in patients with celiac disease and selective IgA deficiency
2003
Celiac disease (CD) and selective IgA deficiency (IgAD) are frequently associated, and share the same genetic background. The aim of the present study was to evaluate both Type 1 and 2 plasma cytokine levels in CD and in CD-IgAD. IL-2, TNF-alpha, IL-10, IL-4 and IL-13 plasma levels were measured both at diagnosis and after a gluten-free diet (GFD) in 32 CD patients, in 27 CD-IgAD patients and in 30 healthy controls. IFN-gamma levels were significantly higher in CD and CD-IgAD than in controls, TNF-alpha displayed significantly higher levels in CD-IgAD when compared both with controls and with CD, and IL-2 was in CD-IgAD significantly increased respect to controls. Kinetics of the Type 1 cyt…
Real-time data processing in the ALICE High Level Trigger at the LHC
2019
At the Large Hadron Collider at CERN in Geneva, Switzerland, atomic nuclei are collided at ultra-relativistic energies. Many final-state particles are produced in each collision and their properties are measured by the ALICE detector. The detector signals induced by the produced particles are digitized leading to data rates that are in excess of 48 GB/$s$. The ALICE High Level Trigger (HLT) system pioneered the use of FPGA- and GPU-based algorithms to reconstruct charged-particle trajectories and reduce the data size in real time. The results of the reconstruction of the collision events, available online, are used for high level data quality and detector-performance monitoring and real-tim…
Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample.
2021
Abstract Objective Tissue factor pathway inhibitor (TFPI) is a potent anticoagulant protein in the extrinsic coagulation pathway. In the present study, we aim to identify the cardiovascular determinants for total TFPI activity and its association with cardiovascular disease (CVD) and total mortality. Methods Total TFPI activity was assessed in a selection of the population-based Gutenberg Health Study (n = 5,000). Statistical analysis was performed to identify the determinants for total TFPI activity as well as the associations with CVD and mortality. Results Multivariable linear regression analysis identified smoking (β 0.095 [0.054–0.136]) as a positive determinant for total TFPI activity…
Potential Roles of Peroxisomes in Alzheimer's Disease and in Dementia of the Alzheimer's Type
2012
In Alzheimer's disease (AD) and dementia of the Alzheimer's type (DAT), the role played by peroxisomes is not well known. Peroxisomes are present in all eukaryotic cells, with the exception of erythrocytes. They are involved in the β-oxidation process of long-chain fatty acids, very-long-chain fatty acids, and branched-chain fatty acids. They participate in the α-oxidation of phytanic acid, the biosynthesis of bile acids, and the breakdown of eicosanoids. Peroxisomes are also involved in the synthesis of specific fatty acids such as docosahexaenoic acid (DHA), which is essential for the brain and retina, and plasmalogens (PLGN), which play crucial roles in neural cells and are essential com…