Search results for "asma"

Specific recommendations for PROs and HRQoL assessment in allergic rhinitis and/or asthma: a GA(2)LEN taskforce position paper

2010

The GA(2)LEN taskforce on Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) published in 2009 a position paper concerning PROS and HRQoL assessment in clinical trials on allergy. Because of the specificity of this topic in asthma and rhinitis, specific recommendations are needed. The aim of this position paper is to define PROs and their meaning in asthma and rhinitis research, explore the available tools to provide criteria for a proper choice, identify patient-related factor which could influence PROs assessment, define specific recommendations for assessment, analysis and results spreading, underline the unexplored areas and unmet needs. PROs assessment is gaini…

Evaluation of Clotting Factor Concentrates for Treatment of Thrombotic Thrombocytopenic Purpura.

2010

Abstract Abstract 3678 Introduction: Thrombotic thrombocytopenic purpura (TTP) is characterized by microthrombi, hemolytic anemia as well as thrombocytopenia. These symptoms are caused by a decreased activity of the protease ADAMTS13 which cleaves the von Willebrand Factor (VWF), due to mutation of the ADAMTS13-gene or autoantibodies. At the moment, the only available immediate therapy is plasmapheresis with Fresh Frozen Plasma (FFP) which may induce side effects. Therefore an alternative therapy might be the treatment with clotting factor concentrates. Methods: 40 plasma samples were tested, consisting of FFP and solvent/detergent treated plasma, four batches of each blood group; VWF/VIII …

Wind tunnel study on the size distribution of droplets after collision induced breakup of levitating water drops

2018

Abstract Wind tunnel experiments on collisions between drop pairs of 2.5 and 0.5 mm diameter have been performed and the coalescence and breakup events have been recorded by a high-speed digital camera. From the comprehensive analysis of the captured images, the most important parameters utilized in numerical models, such as coalescence efficiency, breakup type, number of fragments and fragment size distribution after breakup were determined. The experimentally obtained parameters have been compared to parameterizations based on earlier laboratory studies of Low and List, and on direct numerical simulations. A very good agreement between experimental results and parameterizations has been f…

Laser-Induced Plasma Emission Spectrometric Study of Pigments and Binders in Paper Coatings:  Matrix Effects

1998

Laser-induced plasma emission spectroscopy (LIPS) has been used to study inorganic pigment and organic binder distributions in paper coatings, which are inhomogeneous and porous materials. The plasma was generated by focusing a pulsed XeCl excimer laser beam (diameter 100 μm, irradiance 0.3 GW/cm2) on the sample surface at atmospheric pressure. A gated intensified CCD detector was used to record time-delayed emission spectra. Linear correlations between the LIPS signals and the coat weight and the binder content of the coatings studied were obtained. Emission line intensities from ionic and neutral magnesium atoms were used to evaluate plasma temperature corrections in determining silicon a…

Active spike transmission in the neuron model with a winding threshold manifold

2012

International audience; We analyze spiking responses of excitable neuron model with a winding threshold manifold on a pulse stimulation. The model is stimulated with external pulse stimuli and can generate nonlinear integrate-and-fire and resonant responses typical for excitable neuronal cells (all-or-none). In addition we show that for certain parameter range there is a possibility to trigger a spiking sequence with a finite number of spikes (a spiking message) in the response on a short stimulus pulse. So active transformation of N incoming pulses to M (with M>N) outgoing spikes is possible. At the level of single neuron computations such property can provide an active "spike source" comp…

Flow properties and hydrodynamic interactions of rigid spherical microswimmers.

2017

We analyze a minimal model for a rigid spherical microswimmer and explore the consequences of its extended surface on the interplay between its self-propulsion and flow properties. The model is the first order representation of microswimmers, such as bacteria and algae, with rigid bodies and flexible propelling appendages. The flow field of such a microswimmer at finite distances significantly differs from that of a point-force (Stokeslet) dipole. For a suspension of microswimmers, we derive the grand mobility matrix that connects the motion of an individual swimmer to the active and passive forces and torques acting on all the swimmers. Our investigation of the mobility tensors reveals tha…

Does the Site of Blood Collection in Fish Affect Haematological and Blood Biochemical Results?

2021

The values of haematological and selected blood plasma biochemical parameters of juvenile common carp (Cyprinus carpio Linnaeus, 1758) were compared between blood samples taken from caudal vein and heart to evaluate the influence of blood sampling body site on the obtained results in two groups of fish of different blood sampling order: I – first by caudal and then by cardiac puncture, II – first by cardiac and then by caudal puncture. The obtained results revealed statistically significant (p<0.05) differences only in group I where red blood cell (RBC) count was higher in caudal vein blood, while haematocrit (Ht) value, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), …

The reconstitution of human C1, the first complement component Binding of C1r and C1s to C1q influences the C1q conformation

1981

Digital information receiver based on stochastic resonance

2003

International audience; An electronic receiver based on stochastic resonance is presented to rescue subthreshold modulated digital data. In real experiment, it is shown that a complete data restoration is achieved for both uniform and Gaussian white noise.

Complex singularities in KdV solutions

2016

In the small dispersion regime, the KdV solution exhibits rapid oscillations in its spatio-temporal dependence. We show that these oscillations are caused by the presence of complex singularities that approach the real axis. We give a numerical estimate of the asymptotic dynamics of the poles.