Search results for "asta"

The rxr agonist bexarotene in combination with rosuvastatin inhibits angiotensin-ii induced abdominal aortic aneurysm formation in apoliprotein -e-kn…

2014

Asiantuntevien lukijoiden jäljillä : Alara-lehden lukemistutkimus

2008

Seguidors vencen, un grito de guerra para un rey: Un lema para la virtud de la Fortaleza en Alfonso V el Magnánimo (1423-1458)

2017

espanolLa historia politica de Alfonso V el Magnanimo, Rey de Aragon (1416-1458) permanece asociada, indefectiblemente, a sus derechos sobre el trono de Napoles. Las vicisitudes que vivio desde 1423, cuando Juana II Durazzo lo destituyo como heredero del mismo, hasta lograrlo en 1442, motivaron toda una serie de elementos representativos con los que el soberano busco legitimarse ante sus subditos y contemporaneos. De entre ellos, reclama la atencion el posible uso que el monarca hizo del lema “Seguidors vencen”. El estudio de dicho mote y su posible asociacion al emblema real del Siti Perillos constituyen el objeto del presente articulo. EnglishThe political history of Alfonsus V the Magnan…

Instrucció, 1753, 05, 30

Precedeix al tit.: [creu de Malta Signat al final: "Don Juan Antonio Bringas de la Torre" y rùbrica ms Port. amb orla xil Escut reial xil. a la port Caplletra ornada en la primera p Sign.: [A]-F2 Fules impreses per ambdues cares Reclams

Allogeneic stem cell transplantation for renal cell carcinoma

2011

Allogeneic hematopoietic stem cell transplantation from a compatible donor has been utilized as adoptive immunotherapy in metastatic, cytokine-refractory renal cell carcinoma (RCC). Since the year 2000, several investigators have established that RCC is susceptible to a graft-versus-tumor effect: they reported that patients with renal cancer may have partial or complete disease responses, in the 20-40% range, after allogeneic transplantation following a reduced-intensity regimen. However, transplant-related mortality is still high in the 10-20% range, and responses are rarely durable. Experimental evidence suggests that donor-derived T cells and natural killer cells are the main mediators o…

Innovazione e pianificazione. Una nuova visione per il progetto del territorio provinciale

2012

The regional planning, as for a product of synergies arising from differ- ent agents, is getting more and more such a complex topic, possibly requir- ing a renovation in order to refresh its approach. Thinking over how to plan the territory is not a new process. History teaches that both the evolution and the technological progress have always involved some new needs and alterations of the life styles, consequently producing some renovate models as regards the use of the territory. One of the problem, that has urgently to be dealt with, is the relationship between preservation and innovation since the recent models seem to re- gard the territory as a continuously consumable and renewable re…

Solapamiento del nicho trófico en un área de cría en la costa portuguesa

2002

The diets and the trophic niche overlap between seven flatfish species were studied in a coastal nursery adjoining to the Tagus estuary (Portugal). Fish were sampled monthly, from March to November 1999, using a beach seine. Arnoglossus imperialis (Rafinesque, 1810), Arnoglossus laterna (Walbaum, 1792) and Arnoglossus thori Kyle, 1913, fed mainly on crustaceans. The diets of Buglossidium luteum (Risso, 1810) and Dicologoglossa cuneata (Moreau, 1881) were mainly composed of Bivalvia and Polychaeta, while for Scophthalmus rhombus (Linnaeus, 1758) the main food items were Mysidacea and Teleostei. The diet of Pegusa lascaris (Risso, 1810) was mainly composed by Cumacea, Bivalvia, Decapoda and A…

Carotenoids of two freshwater amphipod species (Gammarus pulex and G. roeseli) and their common acanthocephalan parasite Polymorphus minutus

2004

Carotenoid compositions of two freshwater Gammarus species (Crustacea: Amphipoda) and of their common acanthocephalan parasite Polymorphus minutus were characterized. The effect of carotenoid uptake by the parasite was addressed by comparing the carotenoid content of uninfected and infected female hosts. Using high-pressure liquid chromatography (HPLC), co-chromatography of reference pigments and electron ionization mass spectrometry of collected HPLC fractions (EI-MS), several xanthophylls and non-polar compounds were identified. Seven kinds of carotenoids, mainly xanthophylls, were identified in gammarids. Astaxanthin was predominant, amounting to 40 wt.% of total carotenoid in both uninf…

Thermodynamic versus Conformational Metastability in Fibril-Forming Lysozyme Solutions

2012

The role of intermolecular interaction in fibril-forming protein solutions and its relation with molecular conformation is a crucial aspect for the control and inhibition of amyloid structures. Here, we study the fibril formation and the protein-protein interactions of lysozyme at acidic pH and low ionic strength. The amyloid formation occurs after a long lag time and is preceded by the formation of oligomers, which seems to be off-pathway with respect to fibrillation. By measuring the osmotic isothermal compressibility and the collective diffusion coefficient of lysozyme in solution, we observe that the monomeric solution is kept in a thermodynamically metastable state by strong electrosta…

Receptor Activator of NF-kB (RANK) Expression in Primary Tumors Associates with Bone Metastasis Occurrence in Breast Cancer Patients

2011

Background\ud Receptor activator of NFkB (RANK), its ligand (RANKL) and the decoy receptor of RANKL (osteoprotegerin, OPG) play a pivotal role in bone remodeling by regulating osteoclasts formation and activity. RANKL stimulates migration of RANK-expressing tumor cells in vitro, conversely inhibited by OPG.\ud \ud Materials and Methods\ud We examined mRNA expression levels of RANKL/RANK/OPG in a publicly available microarray dataset of 295 primary breast cancer patients. We next analyzed RANK expression by immunohistochemistry in an independent series of 93 primary breast cancer specimens and investigated a possible association with clinicopathological parameters, bone recurrence and surviv…