Search results for "audit"
showing 10 items of 1421 documents
Opposing health effects of hybridization for conservation
2021
The continuing decline of many natural plant and animal populations emphasizes the importance of conservation strategies. Hybridization as a management tool has proven successful in introducing gene flow to small, inbred populations, but can be also associated with health risks. For example, hybridization can change susceptibility to infection in either direction due to heterosis (hybrid vigor) and outbreeding depression, but such health effects have rarely been considered in the genetic management of populations. Here, we investigated the effects of experimental outcrossing between the critically endangered Saimaa landlocked salmon (Salmo salar m. sebago) and the genetically more diverse A…
Diagnóstico económico-financiero de la empresa cooperativa. Un estudio comparado de los años 2004 y 2007
2013
En este trabajo nos proponemos analizar la evolución económico-financiera de las sociedades cooperativas en los últimos años, especialmente los años 2004 y 2007 por considerar que en el primero de ellos las empresas, en general, gozaban de una cierta estabilidad que desaparece con los efectos de la crisis económica, y 2007 como año en el que sus efectos empiezan a ser percibidos globalmente en el tejido empresarial. En primer lugar evaluaremos la importancia de estas empresas en España. A continuación, tomando como referencia los datos financieros de una muestra de empresas de los años 2004 y 2007, realizaremos un análisis estadístico de significatividad de las diferencias en rentabilidad, …
Discrete cortical representations and their stability in the presence of synaptic turnover
2015
Population imaging in mouse auditory cortex revealed clustering of neural responses to brief complex sounds: the activity of a local population typically falls close to one out of a small number of observed states [1]. These clusters appear to group sets of auditory stimuli into a discrete set of activity patterns and could thereby form the basis for representations of sound categories. However, to be useful for the brain, such representations should be robust against fluctuations in the underlying circuitry, which are significant even in the absences of any explicit learning paradigm [2]. Here we introduce a novel firing rate based circuit model of mouse auditory cortex to study the emerge…
Rola audytu wewnętrznego w kształtowaniu efektywności samorządowej gospodarki finansowej
2015
Potrzeba racjonalizowania wydatków, dążenie do większej dyscypliny finansowej i poszukiwanie oszczędności w ramach prowadzonej gospodarki zasobami rzeczowymi i finansowymi wskazują na konieczność wypracowania i ciągłego doskonalenia mechanizmów (instrumentów) zorientowanych na poprawę efektywności samorządowej gospodarki finansowej. Instrumentem, który może wspomóc kierownictwo jednostki samorządu terytorialnego (JST) w racjonalnym prowadzeniu gospodarki finansowej, chroniąc jednocześnie społeczeństwo przed marnotrawstwem i nieefektywnym wydatkowaniem środków publicznych, jest audyt wewnętrzny. Celem artykułu jest próba identyfikacji znaczenia audytu wewnętrznego dla efektywności gospodarki…
Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome
2021
Simple Summary Lifestyle modifies cancer risk in the general public. How lifestyle modifies cancer risk in individuals carrying the inherited pathogenic gene variants in DNA mismatch repair genes (Lynch syndrome) remains understudied. We conducted a retrospective study with cancer register data to investigate associations between body weight, physical activity, and cancer risk among Finnish Lynch syndrome carriers (n = 465, 54% women). The results of our study indicated that longitudinal weight gain increases cancer risk, whereas being highly physically active during adulthood could decrease cancer risk in men. Further, women were observed to be less prone to lifestyle-related risk factors …
Sydäntautien ehkäisyn aloittamisessa ei alaikärajaa
2021
Towards evidence-based management: A nationwide administrative data-based audit of acute myocardial infarction in Latvia
2019
When care for an individual patient is determined by evidence-based medical guidelines, the management of the whole clinical process also needs to be based on evidence. In Latvia, an careful retros...
Toward Comprehensive Plant Microbiome Research
2020
Microbes have driven eco-evolutionary adaptations organizing biodiversity from the origin of life. They are ubiquitous and abundant, facilitating the biochemical processes that make Earth habitable and shape ecosystem structures, functions, and services. Recent studies reveal that commensalistic and beneficial microbes associated with wild and domesticated plants may aid in establishing sustainable agriculture for a changing climate. However, developing microbe-based biotechnologies and ecosystem services requires a thorough understanding of the diversity and complexity of microbial interactions with each other and with higher organisms. We discuss the hot and blind spots in contemporary re…
Myopia - maailmanlaajuinen epidemia
2021
• Myopian eli likinäköisyyden esiintyvyys on viime vuosikymmeninä lisääntynyt voimakkaasti. • Tähän ovat ilmeisesti vaikuttaneet voimakkaimmin lähikatselun lisääntyminen ja ulkona vietetyn ajan väheneminen. Perintötekijät selittävät myopiasta vain pienen osan. • Ulkoilun lisäämisellä ja pitkäkestoisen lähikatselun välttämisellä on voitu vähentää lasten myopian ilmaantuvuutta. • Useiden silmäsairauksien ja näkövammaisuuden riski lisääntyy myopian voimistuessa. • Atropiinisilmätippojen käytöstä on raportoitu olevan hyötyä likinäköisyyden etenemisen hidastamisessa, mutta pidempiaikaisista hyödyistä ja mahdollisista haitoista tarvitaan seurantatietoa. The prevalence of myopia has increased sig…
Menopause modulates the circulating metabolome: evidence from a prospective cohort study
2022
Abstract Aims We studied the changes in the circulating metabolome and their relation to the menopausal hormonal shift in 17β-oestradiol and follicle-stimulating hormone levels among women transitioning from perimenopause to early postmenopause. Methods and results We analysed longitudinal data from 218 Finnish women, 35 of whom started menopausal hormone therapy during the study. The menopausal transition was monitored with menstrual diaries and serum hormone measurements. The median follow-up was 14 months (interquartile range: 8–20). Serum metabolites were quantified with targeted nuclear magnetic resonance metabolomics. The model results were adjusted for age, follow-up duration, educat…