Search results for "axis"

showing 10 items of 751 documents

Correlation between GP-170 expression, prognosis, and chemoresistance of superficial bladder carcinoma.

2003

To study GP-170 in superficial bladder cancer at initial diagnosis and at recurrence and to evaluate if intravesical chemoprophylaxis modifies the expression of GP-170 in tumor recurrences. GP-170 was retrospectively assessed in 160 patients affected by primary superficial transitional cell carcinoma of the bladder and followed for up to 10 years. Eighty-four patients (52.5%) recurred after transurethral resection (TUR). Adjuvant intravesical chemotherapy after TUR was adopted in 52 patients. The correlations between GP-170 and G-grade, T-category, risk of recurrence and of progression, and adoption of adjuvant intravesical chemotherapy were investigated. The correlations between variations…

AdultMaleCancer Researchmedicine.medical_specialtyPathologymedicine.medical_treatmentUrologySettore MED/24 - UrologiaSuperficial bladder carcinoma GP-170 MDR-1 Prognosis Intravesical chemotherapyInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineCarcinomaHumansATP Binding Cassette Transporter Subfamily B Member 1Stage (cooking)AgedRetrospective StudiesChemotherapyHematologyUrinary bladderbusiness.industryGeneral MedicineMiddle Agedmedicine.diseasePrognosisDrug Resistance MultipleGene Expression Regulation NeoplasticTransitional cell carcinomamedicine.anatomical_structureOncologyUrinary Bladder NeoplasmsChemotherapy AdjuvantDrug Resistance NeoplasmChemoprophylaxisFemaleSuperficial Bladder CarcinomaGenes MDRNeoplasm Recurrence LocalbusinessFollow-Up StudiesJournal of cancer research and clinical oncology
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Orthodontic camouflage versus orthognathic surgery for class III deformity: comparative cephalometric analysis

2017

The objective of this study was to compare different cephalometric variables in adult patients with class III malocclusions before and after treatment, in order to determine which variables are indicative of orthodontic camouflage or orthognathic surgery. The cases of 156 adult patients were assessed: 77 treated with orthodontic camouflage and 79 treated with orthodontics and orthognathic surgery. The following cephalometric variables were measured on pre-treatment (T1) and post-treatment (T2) lateral cephalograms: sella-nasion-A-point (SNA), sella-nasion-B-point (SNB), and A-point-nasion-B-point (ANB) angles, Wits appraisal, facial axis angle, mandibular plane angle, upper and lower inciso…

AdultMaleCephalometric analysisCephalometrymedicine.medical_treatmentOrthognathic surgeryDentistryClass iiiOrthodontics Corrective03 medical and health sciences0302 clinical medicine0502 economics and businessmedicineDeformityHumansOrthodonticsAdult patientsOrthognathic Surgical ProceduresFacial axisbusiness.industry05 social sciencesLateral cephalograms030206 dentistryCross-Sectional StudiesMalocclusion Angle Class IIITreatment OutcomeOtorhinolaryngologyFemale050211 marketingSurgeryMandibular plane angleAnatomic LandmarksOral Surgerymedicine.symptombusinessInternational Journal of Oral and Maxillofacial Surgery
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Orderly display of limb lead ECGs raises Chinese intern’s diagnostic accuracy when determining frontal plane QRS axis

2019

Background: There is limited information on whether the orderly display of limb lead ECGs (electrocardiograms) can facilitate students to determine frontal plane QRS complex wave electrical axis. Objectives: The study investigated whether the orderly display of limb lead ECGs can raise Chinese undergraduate intern’s diagnostic accuracy when determining frontal plane axis. Design: A total of 147 fifth-year undergraduate interns aged between 21 and 25 years were randomly arranged into 2 groups: one group was given classically displayed ECGs of limb leads while the other group was given orderly displayed ECGs of limb leads. They were then taught to determine frontal plane axis with one of the …

AdultMaleChinamedicine.medical_specialtyShort CommunicationelectrocardiographykardiologiaDiagnostic accuracymedical teachingelectrocardiogrammedical learningEducationYoung AdultQRS complexInternal medicinemedicineHumanscardiovascular diseasesLead (electronics)ta315EKGMedical educationlcsh:LC8-6691lcsh:R5-920medicine.diagnostic_testlcsh:Special aspects of educationbusiness.industryClinical Clerkshipfood and beveragesta3141General Medicineta3121diagnostiikkaMedical teachingkoulutusCoronal planecardiovascular systemCardiologyFemaleQrs axisbusinesslcsh:Medicine (General)medical educationElectrocardiographycirculatory and respiratory physiologyMedical Education Online
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Genetic control of immune response in carriers of ancestral haplotype 8.1: the study of chemotaxis.

2007

In all caucasian populations the association of an impressive number of autoimmune diseases with genes from the HLA-B8, DR3 hap- lotype that is part of the ancestral haplotype (AH) 8.1 HLA-A1, Cw7, B8, TNFAB∗a2b3, TNFN∗S, C2∗C, Bf∗s, C4A∗Q0, C4B∗1, DRB1∗0301, DRB3∗0101, DQA1∗0501, DQB1∗0201 has been reported by different research groups. This haplotype, which is more common in northern Europe, is also associated with a number of immune system dysfunctions in healthy subjects. Analyzing the data according to gender, some dysfunc- tions are observed in women but not in men, in agreement with the role of X-linked genes and/or estrogens in the development and progression of autoimmune diseases.…

AdultMaleHeterozygoteResearch groupsNeutrophilsautoimmune diseaseHuman leukocyte antigenBiologyancestral haplotypeimmune responseGeneral Biochemistry Genetics and Molecular BiologyHLA-B8 AntigenImmune systemHLA-DR3 AntigenHistory and Philosophy of ScienceHumansGeneGeneticsGeneral NeuroscienceHaplotypeC4AHealthy subjectsImmunityChemotaxisMiddle AgedHLAChemotaxis LeukocyteHaplotypesImmunologyFemalechemotaxiAnnals of the New York Academy of Sciences
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Comparison of Cortisol Stress Response in Patients with Panic Disorder, Cannabis-Induced Panic Disorder, and Healthy Controls

2018

<b><i>Background/Aims:</i></b> Little research effort has so far been dedicated to the analysis of the hypothalamic-pituitary-adrenal axis of aetiologically differing subgroups of patients with panic disorder (PD). The current study aimed at a deeper understanding of the cortisol stress response in cannabis-induced PD (CIPD) patients. <b><i>Methods:</i></b> Matched groups of 7 PD patients (mean age ± SD: 32.95 ± 9.04 years), 7 CIPD patients (31.94 ± 8.40 years), and 7 healthy controls (HC) (31.13 ± 8.57 years) were included in the study. The Trier Social Stress Test (TSST) was used for stress induction. Salivary cortisol samples were collected…

AdultMaleHypothalamo-Hypophyseal Systemendocrine systemmedicine.medical_specialtyHydrocortisoneSubstance-Related DisordersGastroenterologyFight-or-flight response03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesInternal medicinemedicineTrier social stress testHumansIn patientSalivaCannabisbiologyPanic disorderPanicbiology.organism_classificationmedicine.disease030227 psychiatryPsychiatry and Mental healthClinical Psychologymedicine.anatomical_structurePanic DisorderFemaleCannabismedicine.symptomPsychologyStress Psychological030217 neurology & neurosurgeryHypothalamic–pituitary–adrenal axisHormonal responsePsychopathology
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Hypothalamic-pituitary-thyroid axis in acromegaly

1983

To evaluate the hypothalamic-pituitary-thyroid axis in acromegaly, total and free thyroid hormones and TSH response to TRH were determined in 36 acromegalic patients. In 10 patients, rT3 and thyroxine binding globulin (TBG) were also assayed by radioimmunoassay. In 15 patients the TSH response to TRH was also studied after medical or surgical therapy of the acromegaly. In 34 patients total thyroid hormones were in the normal range whereas two patients had low serum levels of free thyroid hormones. Thirty-two of the acromegalic patients were euthyroid. However, only 43.7% of the euthyroid patients had a normal TSH response to TRH. Nine patients had a reduced TSH rise after TRH, whereas in 4 …

AdultMaleHypothalamo-Hypophyseal Systemendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismThyroid GlandThyrotropinThyroid Function TestsThyroxine-binding globulinEndocrinologyTRH stimulation testInternal medicineAcromegalymedicineHumansEuthyroidThyrotropin-Releasing Hormonebiologybusiness.industryThyroidMiddle Agedmedicine.diseaseHypothalamic–pituitary–thyroid axisThyroxinemedicine.anatomical_structureEndocrinologyHypothalamusAcromegalybiology.proteinTriiodothyronineFemaleThyroid functionbusinesshormones hormone substitutes and hormone antagonistsJournal of Endocrinological Investigation
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Isolated hevein-like domains, but not 31-kd endochitinases, are responsible for IgE-mediated in vitro and in vivo reactions in latex-fruit syndrome.

2005

Background Individuals with natural rubber latex allergy often have immediate reactions to plant-derived foods and fresh fruits, such as avocado and banana. IgE of these patients has been shown to bind endochitinases containing an N-terminal hevein-like domain (HLD). However, evidence on 31-kd endochitinase-induced reactions in vivo is lacking. Objective We sought to assess the clinical significance of 31-kd endochitinases and isolated HLDs in latex-fruit syndrome. Methods The 31-kd endochitinases and corresponding HLDs were purified or produced from avocado, banana, latex, and wheat germ. Skin prick test reactivities against purified proteins were examined in 15 patients with natural rubbe…

AdultMaleLatexImmunologyMolecular Sequence DataEnzyme-Linked Immunosorbent Assaymedicine.disease_causeImmunoglobulin ECross-reactivityMicrobiology03 medical and health sciences0302 clinical medicineFood allergyChitin bindingLatex HypersensitivitymedicineImmunology and AllergyHumansAmino Acid Sequence030304 developmental biologyDNA PrimersSkin Tests0303 health sciencesbiologySequence Homology Amino AcidChemistryPerseaChitinasesfood and beveragesMusaAllergensImmunoglobulin EMiddle Agedmedicine.diseaseIn vitroWheat germ agglutinin3. Good healthProtein Structure Tertiary030228 respiratory systemSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationImmunologybiology.proteinFemaleAntibodyPlant LectinsAnaphylaxisFood HypersensitivityAntimicrobial Cationic PeptidesThe Journal of allergy and clinical immunology
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Enhanced inflammatory and T-helper-1 type responses but suppressed lymphocyte proliferation in patients with seasonal affective disorder and treated …

2015

Abstract Background Animals show seasonal changes in the endocrine and immune system in response to winter stressors. Even though increased inflammation has been implicated in the pathophysiology of depression, whether immune disorder is a key mediator in seasonal affective depression (SAD) is unknown. Here, we hypothesized that short photoperiods in winter may induce inflammatory response, which contributes to SAD, and that light treatments should normalize immune function and improve depressive symptoms. Methods Twenty patients with a diagnosis of SAD, and a score on the HAM-29 of 20 or higher were recruited for this study. Twenty-one healthy subjects with no personal and family history o…

AdultMaleLight therapymedicine.medical_specialtymedicine.medical_treatmentLymphocyteLymphocyte proliferationProinflammatory cytokineInterferon-gammaInternal medicinemedicineAnimalsHumansLymphocytesInflammationAnalysis of VarianceTumor Necrosis Factor-alphaSeasonal Affective DisorderPhototherapymedicine.diseasePsychiatry and Mental healthClinical Psychologymedicine.anatomical_structureCytokineEndocrinologyImmunologyCytokinesMajor depressive disorderFemaleImmune disorderPsychologyHypothalamic–pituitary–adrenal axisInterleukin-1Journal of Affective Disorders
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Effects of resistance training on testosterone metabolism in younger and older men

2015

This study investigated the effects of resistance training (RT) on the metabolism of testosterone (T) in younger (n=5, 28±3yrs.) and older (n=8, 70±2yrs.) men. Experimental heavy resistance exercises (5×10RM leg presses) were performed before and after a 12-month of RT. No age differences were found in the production or metabolic clearance rate of T (determined by stable isotope dilution method), skeletal muscle androgen receptor content or serum LH concentrations due to acute or chronic RT. The T production capacity response to gonadotropin stimulation and the concentrations of the urinary T metabolites (androsterone and etiocholanolone) were lower in the older compared to younger men (p<0…

AdultMaleLuteinizing hormoneAgingmedicine.medical_specialtyta3111AndrosteroneBiochemistryMuscle hypertrophychemistry.chemical_compoundEndocrinologySex hormone-binding globulinInternal medicineEtiocholanoloneGeneticsmedicineHumansTestosteroneMuscle Skeletalta315ExerciseMolecular BiologyTestosteroneAgedEtiocholanoloneAndrosteronebiologyta1184Age FactorsResistance TrainingCell BiologyHypothalamic–pituitary–thyroid axisPatient Outcome AssessmentRenal EliminationAndrogen receptorEndocrinologychemistryReceptors AndrogenIsotope LabelingGnRHbiology.proteinLuteinizing hormoneHormonemedicine.drugExperimental Gerontology
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Efficacy of caspofungin and itraconazole as secondary antifungal prophylaxis: analysis of data from a multinational case registry

2009

Patients surviving invasive fungal disease (IFD) and needing further antineoplastic chemotherapy are at high risk of recurrent fungal infection. In the absence of randomised controlled trials in this area, secondary prophylactic regimens are diverse. From 448 patients registered with the Multinational Case Registry of Secondary Antifungal Prophylaxis, we performed an analysis of patients receiving caspofungin (CAS) or itraconazole (ITC). All patients had an underlying haematological malignancy and had been diagnosed with an episode of IFD earlier in their course of treatment. Data collected comprised demographics, underlying disease, first episode of IFD, antifungal prophylaxis, incidence a…

AdultMaleMicrobiology (medical)medicine.medical_specialtyAntifungal AgentsAdolescentItraconazoleAspergillosisChemopreventionEchinocandinsLipopeptidesYoung Adultchemistry.chemical_compoundCaspofunginInternal medicinemedicineHumansAspergillosisPharmacology (medical)RegistriesMycosisAgedFirst episodebusiness.industryIncidence (epidemiology)Stem cell transplantationGeneral MedicineMiddle Agedmedicine.diseaseSurgeryTransplantationTreatment OutcomeInfectious DiseasesMycoseschemistryHematologic NeoplasmsChemoprophylaxisFemaleAntifungal prophylaxisItraconazoleCaspofunginbusinessmedicine.drugInternational Journal of Antimicrobial Agents
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