Search results for "bali"
showing 10 items of 1017 documents
Backlash against the procedural consensus
2020
While the politics of backlash is typically described as a reaction to policy decisions in favour of minority rights, immigration or globalisation, this essay focuses on the fact that backlash typically also involves a reaction against the procedural consensus liberal democracy is based upon. This challenge to democratic procedures and institutions may be even more dangerous in its effects than the substantial objectives of backlash. I use the composite definition of backlash suggested by Alter and Zürn to assess in how far the attacks on the institutions of liberal democracy have retrograde objectives in themselves or in how far they are merely instrumental to the pursuit of other retrogr…
Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis
2018
Background/aims Multiple sclerosis (MS) is a prototypical autoimmune central nervous system (CNS) disease. Particularly progressive forms of MS (PMS) show significant neuroaxonal damage as consequence of demyelination and neuronal hyperexcitation. Immuno-modulatory treatment strategies are beneficial in relapsing MS (RMS), but mostly fail in PMS. Pregabalin (Lyrica®) is prescribed to MS patients to treat neuropathic pain. Mechanistically, it targets voltage-dependent Ca2+ channels and reduces harmful neuronal hyperexcitation in mouse epilepsy models. Studies suggest that GABA analogues like pregabalin exert neuroprotective effects in animal models of ischemia and trauma. Methods We tested t…
Novel Insights of Effects of Pregabalin on Neural Mechanisms of Intracortical Disinhibition in Physiopathology of Fibromyalgia: An Explanatory, Rando…
2018
Submitted by DSpace Unilasalle (dspace@unilasalle.edu.br) on 2021-09-14T16:51:25Z No. of bitstreams: 1 adeitos.etal.pdf: 2278622 bytes, checksum: dd96bf75fdbab601238c2831da009c73 (MD5) Made available in DSpace on 2021-09-14T16:51:25Z (GMT). No. of bitstreams: 1 adeitos.etal.pdf: 2278622 bytes, checksum: dd96bf75fdbab601238c2831da009c73 (MD5) Previous issue date: 2018 Background: The fibromyalgia (FM) physiopathology involves an intracortical excitability/inhibition imbalance as measured by transcranial magnetic stimulation measures (TMS). TMS measures provide an index that can help to understand how the basal neuronal plasticity state (i.e., levels of the serum neurotrophins brain-derived n…
Pharmacological basis of the anxiolytic and antidepressant properties of Silexan®, an essential oil from the flowers of lavender.
2021
Silexan®, a proprietary essential oil manufactured by steam distillation from Lavandula angustifolia flowers showed pronounced anxiolytic effects in patients with subthreshold anxiety disorders and was also efficacious in patients with Generalized Anxiety disorder (GAD). Moreover, evidences for antidepressant-like properties of Silexan® have been observed in anxious patients suffering from comorbid depressive symptoms and in patients with mixed anxiety-depression disorder (ICD-10 F41.2). In accordance with the clinical data Silexan® is active in several behavioral models in rodents at rather low concentrations indicating potent anxiolytic and antidepressive properties. As possible mechanism…
New insights on water buffalo genomic diversity and post-domestication migration routes from medium density SNP chip data
2018
Made available in DSpace on 2018-12-11T16:52:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-03-02 The domestic water buffalo is native to the Asian continent but through historical migrations and recent importations, nowadays has a worldwide distribution. The two types of water buffalo, i.e., river and swamp, display distinct morphological and behavioral traits, different karyotypes and also have different purposes and geographical distributions. River buffaloes from Pakistan, Iran, Turkey, Egypt, Romania, Bulgaria, Italy, Mozambique, Brazil and Colombia, and swamp buffaloes from China, Thailand, Philippines, Indonesia and Brazil were genotyped with a species-specific medium-dens…
Place and space in home-making processes and the construction of identities in transnational migration
2016
AbstractIn this era of increasing migration and the trend of growing social, political, and cultural integration worldwide, it is questionable whether the concept of home in its traditional meaning still applies or has to be redefined. Many social scientists agree that the mobile individual of the twenty-first century has become uprooted and thus disoriented or that the idea of home has lost its significance. Since home is still closely tied to one’s identity, the current discussions on the construction of identity must also be incorporated in the analytical processes of home-making. The objective is to point out new ways of understanding the idea of home by taking into consideration and an…
Les trajectoires des footballeurs africains à la lumière de la mondialisation.
2010
Depuis la promulgation de l’arrêt « Bosman » en 1995, le nombre de joueurs expatriés recensés dans les principaux championnats européens a considérablement augmenté. Cet article montre que cette augmentation a surtout concerné les joueurs originaires d’Afrique et d’Amérique latine. Leur mobilité intervient dans un contexte très spéculatif au sein duquel de nombreux intermédiaires interagissent pour construire les canaux migratoires permettant aux joueurs de circuler à travers différents pays. Les trajectoires idéales — typiques de joueurs africains en Europe — permettent d’illustrer les logiques sociales, géographiques et économiques à la base de ces flux. Since the “Bosman” law in 1995, t…
Attempts for Common Understanding of the Concept of Worker as a Consequence of Globalisation?
2017
AbstractGlobalisation may concern many different issues, among others, the increase in migration that creates opportunities for all. There should be no doubt that globalisation can bring both positive and negative effects to workers. It can be seen as new opportunities for people, because they can travel, work, learn and live in different countries. Simultaneously however it can be perceived as synonymous to job losses, social injustice, or low environmental, health, and privacy standards. As a result of globalisation, the world is becoming more and more complex and the economic importance of state borders is reduced. It should therefore not raise doubts, that global problems require the ca…
Does Patriotic Vigilance Make Any Sense in the Transnational Arena? A Cosmopolitan Alternative to the Globalization Paradox
2017
We address the issue of the relevance in the transnational arena of the concept of patriotic vigilance, as expressed by French Minister Arnaud Montebourg in 2014. Firstly, we examine the globalization paradox with its underpinnings in the literature and its illustration through the recent Alstom saga. Secondly, we review the idea of a paradigm shift in world monetary affairs signaled by the recent crisis. Finally, drawing on Kant’s ideas on cosmopolitism, we sketch out an alternative to the globalization paradox.
Shaping subjects of globalisation: at the intersection of voluntourism and the new economy
2016
Volunteer tourism is one of the latest branches of the ever expanding globalised tourism. The initiative Workaway, an expression of this trend, was established in the late 90s with the aim of promoting “cultural understanding between different peoples and lands throughout the world”. The figure of the workawayer as a new cosmopolitan subjectivity started to take shape. With the growth of the tourism industry, the Workaway scheme has started to be of interest also to tourism entrepreneurs, especially in the global peripheries such as northern Lapland, home to the indigenous minority language community of the Sámi. By signing up as a volunteer in a heritage tourism resort, the workawayer, the…