Search results for "being"

showing 10 items of 1477 documents

Physical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study.

2022

Contains fulltext : 249581.pdf (Publisher’s version ) (Closed access) PURPOSE: To investigate the impact of physical activity (PA) on the incidence or progression of age-related macular degeneration (AMD) in the general population. DESIGN: Meta-analysis of longitudinal cohort studies. METHODS: We included 14,630 adults with no or early AMD at baseline from 7 population-based studies and examined associations of PA with AMD incidence and progression using multistate models (MSM) per study and subsequent random effects meta-analysis. Age effects were assessed using meta-regression. The main outcome measure was the hazard ratio (HR) for incident early or progression to late AMD. RESULTS: At ba…

Adultmedicine.medical_specialtygenetic structuresPopulationPhysical activitySensory disorders Donders Center for Medical Neuroscience [Radboudumc 12]Cohort Studies03 medical and health sciencesMacular Degeneration0302 clinical medicineSDG 3 - Good Health and Well-beingRisk FactorsInternal medicineAge relatedmedicineHumansLongitudinal StudiesRisk factoreducationExerciseAgededucation.field_of_studybusiness.industryIncidence (epidemiology)IncidenceHazard ratioMacular degenerationMiddle Agedmedicine.diseaseeye diseases3. Good healthOphthalmology030221 ophthalmology & optometryDisease Progression[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiesense organsbusiness030217 neurology & neurosurgeryCohort studyFollow-Up Studies
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Empowering citizens for well-being and chronic disease management with wellness diary.

2010

Chronic conditions closely related to lifestyles are the major cause of disability and death in the developed world. Behavior change is the key to managing well-being and preventing and managing chronic diseases. Wellness diary (WD) is a mobile application designed to support citizens in learning about their behavior, and both making and maintaining behavior changes. WD has been found acceptable, useful, and suitable for long-term use as a part of an intervention. When used independently, however, it does not seem to have enough engaging and motivating features to support adoption and long-term commitment. The main improvement needs identified based on a review of WD-related studies were: p…

Adultself-managementKnowledge managementApplied psychologyMobile computingCognitive-behavior therapyself-observationMedical RecordsPersonalizationBehavior TherapyIntervention (counseling)Health careWeight LossMedicineHumansMedical Informatics ApplicationsElectrical and Electronic EngineeringRisk managementSelf-managementCognitive Behavioral Therapybusiness.industryBehavior changeRehabilitationDisease ManagementGeneral Medicinemobile applicationMiddle AgedModels TheoreticalComputer Science ApplicationsSelf CareWell-beingbusinessSoftwareBiotechnologyIEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society
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Subjective well-being key elements of Successful Aging: A study with Lifelong Learners older adults from Costa Rica and Spain.

2019

Abstract Subjective well-being is a major psychological construct in the research tradition. Along with literature, authors have distinguished between hedonic and eudaimonic well-being. The aim of this study is to determine the role of some psychosocial variables plays in the perceived well-being is conceived from a hedonic or a eudaimonic perspective. The sample consisted of 1016 people of 55 years and older in a Spanish sample and 277 people of 55 years old or older from a Costa Rican sample. Both samples were part of the Longitudinal Older Learners (LOL) study. A structural model with latent variables was estimated with Mplus. The results point out that, the traditional variables include…

Aged 80 and overMaleAgingHealth (social science)030214 geriatricsSuccessful agingPerspective (graphical)Lifelong learningSample (statistics)Middle AgedDevelopmental psychology03 medical and health sciences0302 clinical medicineHumansLearningFemale030212 general & internal medicineGeriatrics and GerontologySubjective well-beingLatent variable modelConstruct (philosophy)PsychologyGerontologyPsychosocialAgedArchives of gerontology and geriatrics
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Multidimensional Sexual Well-being Scale for Older Adults: Validity Evidence from a Polish Sample

2021

Here, we report the results of a Polish adaptation of the Multidimensional Sexual Well-being Scale (MSWBS) for older adults. The MSWBS is a short self-report scale for assessing the five dimensions of an individual's sexual well-being: frequency of caressing, sexual intimacy, sexual compliance, sexual satisfaction, and sexual distress. The aim of our adaptation was to examine the utility of the scale in a country with conservative views on the sexuality of older people, which will help health care providers and researchers to better understand the sexual needs of older people. The study included 507 participants, aged 60-92. We found the reliability of the scale to be satisfactory (Cronbach…

Aged 80 and overPsychometricsSexual Behaviormedia_common.quotation_subjectReproducibility of ResultsLife satisfactionHuman sexualityMiddle AgedConfirmatory factor analysisClinical PsychologyDistressCronbach's alphaSurveys and QuestionnairesScale (social sciences)Well-beingHumansPolandPsychologyAgedClinical psychologyDiversity (politics)media_commonJournal of sex and marital therapy
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Happiness in advanced adulthood and elderly: The role of positive emotions, flourishing and mindfulness as wellbeing factors for successful ageing

2019

This study critically analyses the role of Happiness among the Portuguese elderly. The term is understood as a grouping of variables including Subjective Well-being, defined by satisfaction with life, positive and negative affects, flourishing, optimism and pessimism, positive and negative emotions, meaning of life, religiosity, Spirituality, and mindfulness. The qualities of Happiness are explored as they contribute to successful ageing and higher levels of Happiness in the elderly. We conducted a correlational study of 329 participants, aged 55 to 98 years. We used several questionnaires to gather data as a socio-demographic questionnaire, Satisfaction with Life Scale (SWLS), Positive and…

AgeingMindfulness AttentionHappinessWell-beingFlourishing:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍASatisfaction with Life
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Do aging employees benefit from self-regulative strategies? : A follow-up study

2020

SOC-strategies (selection, optimization, and compensation) are crucial for well-being and adaptation throughout the life course. The workforce is aging rapidly, thus the age-conditional premises of SOC theory require attention. This study explored (1) whether older employees used SOC strategies more often (compared to younger employees), and (2) whether older employees benefited more from SOC strategies in relation to occupational well-being (job burnout, work engagement). The study was based on follow-up data including three occupational subsamples of different age (N = 1,020). There were no significant age-conditional differences in the take-up of SOC strategies. However, older (white-col…

AgingHealth (social science)Process managementSocial Psychology515 Psychologytyöhyvinvointiage-conditional effectsselectioncompensation03 medical and health sciences0504 sociologyitsesäätely (psykologia)otorhinolaryngologic diseasesHumansoccupational well-beingikääntyvät työntekijättyöelämäAdaptation (computer science)Selection (genetic algorithm)sopeutuminen030505 public healthCompensation (psychology)05 social sciencesFollow up studies050401 social sciences methodsfollow-up studyikääntyminen8. Economic growthWorkforceLife course approachseurantatutkimusGeriatrics and Gerontology0305 other medical sciencePsychologyoptimizationpsychological phenomena and processesFollow-Up Studies
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Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

2021

Abstract Background Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation in these measures in populations has become a major goal in the field. Results Leveraging DNA methylation and SNP data from more than 40,000 individuals, we identify 137 genome-wide significant loci, of which 113 are novel, from genome-wide association study (GWAS) meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels, respectively. We find evidence for shared genetic loci ass…

AgingMultifactorial InheritanceBLOODEpigenetic clock05 Environmental SciencesbiomarkkeritGenome-wide association studyQH426-470Epigenesis Genetic/dk/atira/pure/core/keywords/icep0302 clinical medicineBiomarkers of agingGWASBiology (General)AdiposityGenetics11832 Microbiology and virology0303 health sciences318 Medical biotechnologyDNA methylation1184 Genetics developmental biology physiologygenomiikkaDna Methylation ; Epigenetic Clock ; Gwasddc:DNA-metylaatioINSIGHTSC-Reactive ProteinepigenetiikkaDNA methylationMENDELIAN RANDOMIZATION/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingEducational StatusICEPGenetic MarkersPROVIDESSUSCEPTIBILITY LOCIBioinformaticsQH301-705.5GenomicsBiology03 medical and health sciencesNHLBI Trans-Omics for Precision Medicine (TOPMed) ConsortiumAGESDG 3 - Good Health and Well-beingPlasminogen Activator Inhibitor 1REGRESSIONGeneticsHumansEpigeneticsGeneMETAANALYSIS030304 developmental biologyGenome HumanResearchGenetics of DNA Methylation Consortium06 Biological SciencesLipid MetabolismHuman geneticsGenetic architectureImmunity InnateikääntyminenGenetic LociCpG Islands08 Information and Computing Sciences3111 BiomedicineENRICHMENTepigenetic clock030217 neurology & neurosurgeryBiomarkersGenome-Wide Association StudyGranulocytes
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Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness…

2011

Carotid intima media thickness (cIMT) and plaque determined by ultrasonography are established measures of subclinical atherosclerosis that each predicts future cardiovascular disease events. We conducted a meta-analysis of genome-wide association data in 31,211 participants of European ancestry from nine large studies in the setting of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. We then sought additional evidence to support our findings among 11,273 individuals using data from seven additional studies. In the combined meta-analysis, we identified three genomic regions associated with common carotid intima media thickness and two different regions a…

AgingMultifunction cardiogramGenome-wide association studyDiseaseCoronary Artery Disease030204 cardiovascular system & hematologyCarotid Intima-Media ThicknessCoronary artery diseaseCohort Studies0302 clinical medicinecardiovascular diseaseRisk FactorsAging/geneticsgeneticsMyocardial infarctionEuropean Continental Ancestry Group/geneticsriskPlaque0303 health scienceseducation.field_of_studyGenomeCoronary Artery Disease/geneticsHeartSingle NucleotidePlaque Atherosclerotic/geneticsMiddle AgedPlaque Atherosclerotic3. Good healthPhenotypeHeart/physiopathologyCardiologyHumanAdultmedicine.medical_specialtygenetic epidemiologyGenotypesubclinical atherosclerosisPopulationSingle-nucleotide polymorphismBiologyPolymorphism Single NucleotideWhite PeopleArticle03 medical and health sciencesSDG 3 - Good Health and Well-beingInternal medicinemedicinecohort studyHumanscarotid intima media thicknessGenetic Predisposition to DiseasePolymorphismeducation030304 developmental biologyAgedAtherosclerotic/geneticsGenome Humanmedicine.diseaseAtherosclerosismeta-analysisAtherosclerosis/geneticsIntima-media thicknessGenetic LociGenome-Wide Association Study
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Update on the ESCEO recommendation for the conduct of clinical trials for drugs aiming at the treatment of sarcopenia in older adults

2020

Abstract Background In 2016, an expert working group was convened under the auspices of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and formulated consensus recommendations for the conduct of clinical trials for drugs to prevent or treat sarcopenia. Aims The objective of the current paper is to provide a 2020 update of the previous recommendations in accordance with the evidence that has become available since our original recommendations. Methods This paper is based on literature reviews performed by members of the ESCEO working group and followed up with face to face meetings organized for the whole group to make amendments and discuss…

AgingSarcopeniaGeriatrics & GerontologyStandardizationDiseaseReviewRecommendationsFace-to-face0302 clinical medicineQUALITY-OF-LIFEGAIT SPEEDClinical trial; Drug registration; Guidelines; Recommendations; Sarcopenia; Treatment; Aged; Humans; Muscle Strength; Osteoarthritis; Osteoporosis; Pharmaceutical Preparations; Sarcopenia030212 general & internal medicineMUSCLE MASSDIETARY-PROTEINClinical trialPhysical limitationsPharmaceutical Preparations/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPatient-reported outcomeGRIP STRENGTHLife Sciences & Biomedicinemedicine.medical_specialtyNUTRITIONAL-STATUSBODY-COMPOSITION030209 endocrinology & metabolismGuidelines03 medical and health sciencesClinical trial · Sarcopenia · Guidelines · Recommendations · Drug registration · TreatmentSDG 3 - Good Health and Well-beingOsteoarthritismedicineHumansMuscle StrengthDrug registrationAgedScience & Technologybusiness.industryWORKING GROUPmedicine.diseaseComorbidityClinical trialTreatmentSarcopeniaPATIENT-REPORTED OUTCOMESPhysical therapyOsteoporosisGeriatrics and GerontologyPHYSICAL PERFORMANCEbusinessAging Clinical and Experimental Research
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The age and well-being “paradox”: a longitudinal and multidimensional reconsideration

2022

This paper explores qualifcations to the much-discussed paradox that although aging is associated with multiple physical and social losses, subjective well-being (SWB) is stable or increasing in later life. We explore age-related changes in cognitive, afective, and eudaimonic dimensions in three waves of data spanning up to 15 years from the Norwegian NorLAG study (N=4,944, age 40−95). We employ fxed-efect models to examine the nature and predictors of aging efects on SWB. Results indicate a general pattern of stability well into older age, but negative changes in advanced age across well-being measures. Declines in SWB are less pronounced and with a later onset for the cognitive compared w…

AgingSubjective well-beingAffectEngagementHealth (social science)VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Geriatri: 778Life satisfactionGeriatrics and GerontologyVDP::Samfunnsvitenskap: 200::Sosiologi: 220
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