Search results for "blas"

Sulphate removal over barium-modified blast-furnace-slag geopolymer

2016

Blast-furnace slag and metakaolin were geopolymerised, modified with barium or treated with a combination of these methods in order to obtain an efficient SO4(2-) sorbent for mine water treatment. Of prepared materials, barium-modified blast-furnace slag geopolymer (Ba-BFS-GP) exhibited the highest SO4(2-) maximum sorption capacity (up to 119mgg(-1)) and it compared also favourably to materials reported in the literature. Therefore, Ba-BFS-GP was selected for further studies and the factors affecting to the sorption efficiency were assessed. Several isotherms were applied to describe the experimental results of Ba-BFS-GP and the Sips model showed the best fit. Kinetic studies showed that th…

Sulphate removal over barium-modified blast-furnace-slag geopolymer

2016

Blast-furnace slag and metakaolin were geopolymerised, modified with barium or treated with a combination of these methods in order to obtain an efficient SO42− sorbent for mine water treatment. Of prepared materials, barium-modified blast-furnace slag geopolymer (Ba-BFS-GP) exhibited the highest SO42− maximum sorption capacity (up to 119 mg g−1) and it compared also favourably to materials reported in the literature. Therefore, Ba-BFS-GP was selected for further studies and the factors affecting to the sorption efficiency were assessed. Several isotherms were applied to describe the experimental results of Ba-BFS-GP and the Sips model showed the best fit. Kinetic studies showed that the so…

The vesicular transfer of CLIC1 from glioblastoma to microvascular endothelial cells requires TRPM7.

2018

Chloride intracellular channel 1 (CLIC1) is highly expressed and secreted by human glioblastoma cells and cell lines such as U87, initiating cell migration and tumor growth. Here, we examined whether CLIC1 could be transferred to human primary microvascular endothelial cells (HMEC). We previously reported that the oncogenic microRNA, miR-5096, increased the release of extracellular vesicles (EVs) by which it increased its own transfer from U87 to surrounding cells. Thus, we also examined its effect on the CLIC1 transfer. In homotypic cultures, miR-5096 did not increase the expression of CLIC1 in U87 nor in HMEC. However, the endothelial CLIC1 level increased after exposure to EVs released b…

Does the evidence matter in medicine? The retinoblastoma paradigm.

2007

Retinoblastoma (Rb) is the most common intraocular malignant tumour in childhood, with an incidence of 1 in 15,000 live births. Complete information on this rare tumour can be easily accessed through the internet, although many aspect concerning the aetiology and pathogenesis of the disease, are still controversial. The "two hit" theory, formulated in 1971 to explain the variegated clinical expression of the disease, is based on the idea that single gene mutation may determine the development of cancer. However, this view does not take into account the most recent evidences showing the role of aneuploidy and chromosome instability in cancer. Also, a number of other genes and epigenetic mech…

Impacto del miRNA-200c sobre el mecanismo de migración celular en el glioblastoma.Relación con los patrones de amplificación de EGFR.

2016

El Glioblastoma Multiforme (GB), la neoplasia primaria del SNC más importante en adultos, por su frecuencia y agresividad, se muestra como paradigmática de los procesos de infiltración y angiogénesis en las neoplasias. Su localización en el sistema nerviosos central, su alta capacidad invasiva y las consecuencias de una angiogénesis displasica hacen del GB una enfermedad neoplásicas altamente invalidante y de evolución fatal, en la que las distintas acciones terapéuticas se muestran ineficaces. Este trabajo realiza un estudio clínico, morfológico ,genético y epigenético de 46 casos de GB primarios. Se describe un grupo de miRNAs no descritos anteriormente en el GB. Se estableció la correlac…

Estudio del contenido y del estado mitocondrial en el blastocisto humano

2022

El contenido de ácido desoxirribonucleico (ADN) mitocondrial (ADNmt) por célula como marcador de viabilidad embrionaria se propuso como una estrategia muy innovadora para la priorización en la selección de embriones humanos en los tratamientos reproducción asistida, siendo los embriones con menor contenido mitocondrial por célula los candidatos a ser transferidos. La hipótesis de partida se basaba en que dichos embriones presentarían un estado metabólico más apropiado y un menor estrés celular, los cuales se traducirían en una mayor probabilidad de implantación. La elevada expectación inicialmente generada alrededor de este marcador, vino acompañada de publicaciones con resultados contradic…

Espais modificats

2002

Aproximació al desenvolupament arquitectònic del campus de Blasco Ibáñez de la Universitat de València i, en especial, a les obres de Moreno Barberá.

Kolesterolin esiintyminen ihmisen hermostollisissa syöpäsoluissa

2008

Mouse A6 stem cells release active FGF-2 into extracellular space through plasma membrane vesicles

2007

In this study, mouse mesoangioblasts were seeded onto bidimensional matrices within three-dimensional porous scaffolds of poly (L-lactic acid) (PLLA), in the presence or absence of a type I collagen coating. The cells were observed under a scanning electron microscope and tested for their adhesion, survival and proliferation. Immunolocalization of heat shock protein (Hsp) 70, an abundant and ubiquitous intracellular protein in these cells, was also performed in sectioned cell-containing scaffolds under a confocal fluorescence microscope to determine if in situ analysis of intracellular constituents was feasible. The data show that PLLA films allow direct cell adhesion and represent an optim…

Segmental resection for the excision of two multicystic ameloblastoma

2014

Objectives. The purpose of this study was addressed at the understanding and management in the ameloblastoma treatment, performing a segmental surgical resection. Ameloblastoma represents nearly 1% of all neoplasm located  Annali di Stomatologia 2014; Suppl. 3 to n. 2: 1-41 15 in the oral cavity. In 80% of cases it could be found in the mandible, of these lesions 70% are located in the molar re- gion or the ascending ramus, 20% in the premolar region and 10% in the anterior part. It is considered as a benign neoplasm with slow growing-pattern and locally aggressive behaviour. Methods. On the basis of clinicoradiological findings, ameloblastoma is divided into 3 groups: solid or multicyst…