Search results for "bleeding"

showing 10 items of 249 documents

Hereditary combined deficiency of the vitamin K-dependent clotting factors

2010

Abstract Hereditary combined vitamin K-dependent clotting factors deficiency (VKCFD) is a rare congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X as well as natural anticoagulants protein C, protein S and protein Z. The spectrum of bleeding symptoms ranges from mild to severe with onset in the neonatal period in severe cases. The bleeding symptoms are often life-threatening, occur both spontaneously and in a surgical setting, and usually involve the skin and mucosae. A range of non-haemostatic symptoms are often present, including developmental and skeletal anomalies. VKCFD is an autosomal recessive disorder caused by mutations in …

Vitaminmedicine.medical_specialtyVitamin KCoagulation Factor Deficiencylcsh:MedicineReviewGastroenterologyProtein SProtein SSettore MED/15 - Malattie Del Sanguechemistry.chemical_compoundBlood Coagulation Disorders InheritedInternal medicineVitamin K deficiencymedicineHumansGenetics(clinical)Pharmacology (medical)VITAMIN K DEPENDENT CLOTTING FACTORS RARE INHERITED BLEEDING DISORDERSCongenital Bleeding DisorderGenetics (clinical)Medicine(all)Clotting factorbiologybusiness.industrylcsh:RVitamin K2WarfarinInfant NewbornGeneral MedicineBlood Proteinsmedicine.diseaseBlood Coagulation FactorsRecombinant ProteinschemistryCarbon-Carbon LigasesImmunologybiology.proteinVitamin K Deficiencybusinessmedicine.drugProtein C
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Non-surgical periodontal treatment with a new ultrasonic device (Vectortm-ultrasonic system) or hand instruments. A prospective, controlled clinical …

2004

Objectives: The aim of this prospective, randomized, controlled clinical study was to compare the effectiveness of a newly developed ultrasonic device to that of scaling and root planing for non-surgical periodontal treatment. Material and Methods: Thirty-eight patients with moderate to advanced chronic periodontal disease were treated according to an “one-stage procedure” with either a newly developed ultrasonic device (VUS) (Vector™-ultrasonic system) or scaling and root planing (SRP) using hand instruments. Clinical assessments by plaque index (PlI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), gingival recession (GR), and clinical attachment level (CAL) were made …

Wilcoxon signed-rank testbusiness.industryBleeding on probingDentistryDental Plaque Indexlaw.inventionScaling and root planingRandomized controlled triallawmedicinePeriodonticsmedicine.symptombusinessProspective cohort studyLead (electronics)Gingival recessionJournal of Clinical Periodontology
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Impact of monopolar and bipolar endometrial resection on abnormal uterine bleeding

2013

Study Objective. To compare two procedures for endometrial resection: resectoscopy with monopolar knife versus resectoscopy with bipolar knife. Patients and methods. 76 perimenopausal patients affected by DUB (Dysfunctional Uterine Bleeding), no longer wishing to remain pregnant and having failed to respond to pharmacological treatment, underwent endometrial ablation with monopolar loop (group A: 38 women) or bipolar loop (group B: 38 women). Operative parameters, complication rate, menstrual outcome were considered. Results. Operative time was no different between groups. The amount of distention fluid adsorbed was significantly higher in group A than in group B, and late cumulative compli…

abnormal uterine bleedingSettore MED/40 - Ginecologia E Ostetricia
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Management of anemia: blood loss in orthopaedic surgery

2010

Major ortopaedic surgery and high energy trauma are often responsible of acute bleeding. Long bones and pelvis fractures are correlated with increased blood loss. The final consequence of a major bleeding is hypovolemic shock. The reduced oxygen tension of tissue could be responsible of heart attack, arrythmia, ictus, multi organ deficiency. For these reasons, it is important to immediately recognize and correct all potential bleeding in order to avoid complications. In orthopaedics the elective treatments in the managenment of hypovolemia are different. Blood banks and allogenic blood components have had an important impact on operative treatment and health care worldwide. erythropoietin h…

anemia erythropoietin bleeding hypovolemia blood loss.Settore MED/33 - Malattie Apparato Locomotore
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Left Atrial Remodeling and Brain Natriuretic Peptide Levels Variation after Left Atrial Appendage Occlusion

2021

Background: Few data are available about brain natriuretic peptide (BNP) variation and left atrial remodeling after the left atrial appendage occlusion (LAAO) technique. Methods: Prospective study included all consecutive patients successfully implanted with an LAAO device. Contrast-enhanced cardiac computed tomography (CT) was performed before and 6 weeks after the procedure with reverse left atrial remodeling defined by an increase in LA volume &gt

atrial remodelingmedicine.medical_specialtyleft atrial appendage occlusionmedicine.medical_treatmentPopulation030204 cardiovascular system & hematologyLeft atrial appendage occlusionArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicinebleeding riskInternal medicinemedicineatrial fibrillation030212 general & internal medicinecardiovascular diseasesThrombuseducationeducation.field_of_studyCreatinineEjection fractionbusiness.industryRAtrial fibrillationGeneral Medicineatrial cardiopathyBrain natriuretic peptidemedicine.diseasechemistryCardiologycardiovascular systemMedicinebusinessBlood samplingBNPJournal of Clinical Medicine
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ChemInform Abstract: Cyclooxygenase Inhibitors - Current Status and Future Prospects

2010

Prostaglandins are formed from arachidonic acid by the action of cyclooxygenase and subsequent downstream synthetases. Two closely related forms of the cyclooxygenase have been identified which are now known as COX-1 and COX-2. Both isoenzymes transform arachidonic acid to prostaglandins, but differ in their distribution and their physiological roles. Meanwhile, the responsible genes and their regulation have been clarified. COX-1, the pre-dominantly constitutive form of the enzyme, is expressed throughout the body and performs a number of homeostatic functions such as maintaining normal gastric mucosa and influencing renal blood flow and platelet aggregation. In contrast, the inducible for…

biologyColorectal cancerAngiogenesisGeneral MedicinePharmacologymedicine.diseaseIsozymeBleeding diathesischemistry.chemical_compoundchemistryRheumatoid arthritismedicinebiology.proteinArachidonic acidCyclooxygenaseHomeostasisChemInform
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Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC

2020

Background: Careful assessment of bleeding history is the first step in the evaluation of patients with mild/moderate bleeding disorders, and the use of a bleeding assessment tool (BAT) is strongly encouraged. Although a few studies have assessed the utility of the ISTH-BAT in patients with inherited platelet function disorders (IPFD) none of them was sufficiently large to draw conclusions and/or included appropriate control groups. Objectives: The aim of the present study was to test the utility of the ISTH-BAT in a large cohort of patients with a well-defined diagnosis of inherited platelets disorder in comparison with two parallel cohorts, one of patients with type-1 von Willebrand disea…

bleeding assessment toolSYMPTOMSMedicina Clínica030204 cardiovascular system & hematologyBLEEDING DISORDERS0302 clinical medicinePlateletINHERITED PLATELET DISORDERSUTILITYRISKbleeding disordersCommunicationbleeding assessment tool; bleeding diathesis; bleeding disorders; inherited platelet disorders; plateletsbleeding diathesisHematologyPLATELETSvon Willebrand DiseasesplateletsBLEEDING DIATHESISLife Sciences & BiomedicineVON-WILLEBRAND-DISEASEmedicine.medical_specialtyCIENCIAS MÉDICAS Y DE LA SALUDPlatelet Function TestsPlatelet disorderQUESTIONNAIREinherited platelet disorderHemorrhageDIAGNOSIS03 medical and health sciencesInternal medicineSCOREmedicineVon Willebrand diseaseHumansHematologíaIn patientbleeding disorderBLEEDING ASSESSMENT TOOLScience & Technologybleeding diathesibusiness.industrySettore MED/09 - MEDICINA INTERNAMILDmedicine.diseaseLarge cohortBleeding diathesisPeripheral Vascular Diseaseinherited platelet disordersCardiovascular System & CardiologyBlood Platelet Disordersbusiness
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A perioperative uncontrollable bleeding in an elderly patient with acquired hemophilia A: a case report

2013

Key Clinical Message Acquired hemophilia A should be taken into account in the differential diagnosis of perioperative bleeding in patients without any apparent reason for activated partial thromboplastin time prolongation.

bleeding disordersPediatricsmedicine.medical_specialtymedicine.diagnostic_testAcquired hemophilia A; bleeding disorders; bypassing agentsbusiness.industryAcquired hemophilia ASettore MED/41 - AnestesiologiaAcquired hemophilia A bleeding disorders bypassing agents.Case ReportsGeneral MedicinePerioperativehemic and lymphatic diseasesAcquired hemophiliaMedicineIn patientDifferential diagnosisbusinessElderly patientbypassing agentsPartial thromboplastin time
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Floor of the mouth hemorrhage subsequent to dental implant placement in the anterior mandible

2019

Abstract Complications in dental implant surgery are possible. Bleeding complications have been described that may be serious, particularly in the floor of the mouth. We present two cases of sublingual hematomas during dental implant osteotomies that impeded but did not close the airway. The clinical courses of these patient’s complications are reviewed. One patient had immediate hematoma formation while the other developed a hematoma overnight, presenting the next day. The treatment rendered was a precautionary in-hospital tracheotomy for the first patient and only compression control for the second. Bleeding complications during dental implant placement in the anterior mandible can be ser…

body regionsanastomosecortical perforationstomatognathic systemcomplicationshematomaCase SeriesbleedingosteotomyClinical, Cosmetic and Investigational Dentistry
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Influence of Biologically Oriented Preparation Technique on Peri-Implant Tissues; Prospective Randomized Clinical Trial with Three-Year Follow-Up. Pa…

2019

Purpose: The objective of this prospective randomized clinical trial (RCT) was to analyze and compare the clinical behavior of three types of prosthesis supported by single implants in the posterior region after three years of functional loading. Materials and methods: Seventy-five implants were divided into three groups according to the type of prosthetic restoration: screw-retained crown (group GS); cemented crown without finishing line (biologically oriented preparation technique) (group GBOPT); and conventional cemented crown with finishing line (group GCC). After three years in function, clinical parameters (presence of keratinized mucosa, probing depths, bleeding on probing, and radio…

complicationsmedicine.medical_treatmentRadiographyBleeding on probingPeriDentistryProsthesisCrown (dentistry)Articlelaw.invention03 medical and health sciencesimplant-supported prosthesis0302 clinical medicineRandomized controlled triallaw0502 economics and businessmedicinebusiness.industry05 social sciencesSoft tissue030206 dentistryGeneral MedicineBOPTscrew-retainedbone loss and clinical parameterscemented050211 marketingImplantmedicine.symptombusinesssoft tissuesJournal of Clinical Medicine
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