Search results for "bone"

Bone-Healing Pattern on the Surface of Titanium Implants at Cortical and Marrow Compartments in Two Topographic Sites: an Experimental Study in Rabbi…

2018

This study evaluates the bone-healing patterns on the surface of titanium implants at the cortical and marrow compartments of bicortically-installed implants in the diaphysis and metaphysis of rabbit tibiae. In 27 New Zealand rabbits, two implants, one for each macro-design and with equal resorbable blasted media (RBM) implant surfaces, were randomly implanted in the diaphysis or metaphysis of each tibia. The flaps were sutured to allow submerged healing. The animals were sacrificed after two, four, or eight weeks, with nine weeks used for the period of healing. Ground sections were prepared and analyzed. No statistically significant differences were found between the two groups for newly f…

Comparación de implantes transmucosos con cuello convergente frente a implantes sin cuello

2022

En los últimos años, se han realizado varios estudios clínicos y revisiones sistemáticas para comparar los implantes “Bone-level” (BL) y “Tissue-level”(TL). Aunque los resultados de la última revisión sistemática realizada al principio de este trabajo de tesis que analizaba las diferencias entre los implantes dentales BL y TL en sitios únicos o múltiples no mostraban diferencias en términos clínicos y radiográficos, probablemente debido al uso del “Platform-switching” en la implantología moderna. Por otro lado, hay muy pocos estudios en la literatura que comparen los implantes BL y TL en términos de propiedades mecánicas, especialmente los implantes TL con cuellos convergentes, que son cada…

Assessing osseointegration of metallic implants with boronized surface treatment

2020

Background Modification of endosteal implants through surface treatments have been investigated to improve osseointegration. Boronization has demonstrated favorable mechanical properties, but limited studies have assessed translational, in vivo outcomes. This study investigated the effect of implant surface boronization on bone healing. Material and Methods Two implant surface roughness profiles (acid etched, machined) in CP titanium (type II) alloy implants were boronized by solid-state diffusion until 10-15µm boron coating was achieved. The surface-treated implants were placed bilaterally into 5 adult sheep ilia for three and six weeks. Four implant groups were tested: boronized machined …

Formation of nanosized strontium substituted hydroxyapatites

2012

Incorporation of specific elements into calcium phosphates offers the combination of a bioactive material and a therapeutic effect. This is important for improving the integration of implants as well as treating medical conditions. Strontium is a suitable candidate and displays the ability to stimulate bone growth and reducing bone resorption. This study investigated the formation of strontium carbonated hydroxyapatite nanoparticles from an amorphous phase. Crystallization of carbonated hydroxyapatite occurred at 585 o C, but samples with an intended 25% and 75% replacement of calcium with strontium crystallized at 624 o C. Heat treatment at the crystallization temperature revealed that str…

Mixed Epidermal Cell Lymphocyte Reaction: HLA-DR+ Cells Exhibit a Greater Immunostimulatory Activity than CD1a+ Cells

1995

Induction and expression of immunity depends upon processing and presentation of antigens to T-cells by bone marrow derived HLA-DR+ antigen presenting cells (APC). In the induction of immunity to cutaneous antigens, the initial stages of this process begin within the skin itself, and both epidermis and dermis contain bone-marrow derived cells that have the capability of processing and presenting antigens. In normal epidermis, HLA-DR expression is believed to be confined to Langerhans cells with Birbeck granules and indeterminate cells without Birbeck granules. In diseased skin, particularly the inflammatory dermatoses, HLA-DR is commonly expressed by keratinocytes and has been related to th…

Prognostic Relevance of CCN3 in Bone Sarcomas

2010

Osteosarcomas and Ewing’s sarcoma (EWS) are aggressive malignant bone tumors. In both cases, prognostic markers are lacking. Presently, only clinical features are widely accepted as prognostic indicators. In this study we assessed the prognostic value of CCN3 (Nov), a matricellular protein that belong to the CCN family of regulatory proteins, whose members were shown to play crucial roles in bone formation. In osteosarcomas, CCN3 expression levels represent a useful tool to early identification of patients with different prognosis. In both osteosarcomas and Ewing’s sarcomas, the expression of a full length CCN3 protein was associated to a worse prognostic and a higher risk to developing met…

Parathyroid Hormone Related Protein (PTHrP)-Associated Molecular Signatures in Tissue Differentiation and Non-Tumoral Diseases

2023

Cultures in interaction : construction of ethnic identities in Amy Tan's "The bonesetter's daughter"

2007

Satyrae del ilustrado portugués D. Francisco Botelho de Moraes e Vasconcelos (1670-1747): introducción, edición latina, traducción y comentario de fu…

2013

Nuestro trabajo consiste básicamente en: 1) Una introducción que aborda: a) la vida y obra del ilustrado portugués D. Francisco Botelho de Moraes e Vasconcelos (1670-1747), miembro honorario de la Real Academia Española y autor de la obra latina Satyrae; b) la vida y obra de D. Juan González de Dios (1684-1761), Catedrático de Prima de Humanidad de la Universidad de Salamanca, que escribió un comentario a dicha obra titulado: Notae ad Satyras. 2) Una edición crítica del texto latino de las Satyrae de Botelho y de las Notae ad Satyras de González de Dios. 3) Una traducción castellana completa. No existía anteriormente ninguna traducción a ninguna lengua moderna. 4) Numerosas notas que ayudan…

Pain neuroscience education and physical exercise for patients with chronic spinal pain in primary healthcare: a randomised trial protocol.

2019

AbstractBackgroundChronic musculoskeletal pain affects more than 20% of the population, and the prevalence is increasing, causing suffering, loss of quality of life, disability, and an enormous expenditure on healthcare resources. The most common location for chronic pain is the spine. Many of the treatments used are mainly passive (pharmacological and invasive) and poor outcomes. The treatments currently applied in the public health system do not comply with the recommendations of the main clinical practice guidelines, which suggest the use of educational measures and physical exercise as the first-line treatment. A protocol based on active coping strategies is described, which will be eva…