Search results for "bones"
showing 10 items of 279 documents
RGD-mimic polyamidoamine-montmorillonite composites with tunable stiffness as scaffolds for bone tissue-engineering applications
2017
This paper reports on the development of montmorillonite (MMT)-reinforced hydrogels, based on a peptidomimetic polyamidoamine carrying guanidine pendants (AGMA1), as substrates for the osteo-induction of osteoblast precursor cells. AGMA1 hydrogels of various degrees of crosslinking responded favourably to MMT reinforcement, giving rise to composite hydrogels with shear storage modulus G', when fully swollen in water, up to 200 kPa, i.e. 20 times higher than the virgin hydrogels and of the same order or higher than other hydrogel-based composites proposed for orthopaedic applications. This significant improvement was ascribed to the effective interpenetration between the polymer matrix and t…
Reconstructing Bronze Age diets and farming strategies at the early Bronze Age sites of La Bastida and Gatas (southeast Iberia) using stable isotope …
2020
The El Argar society of the Bronze Age in the southeast of the Iberian Peninsula (2200–1550 cal BCE) was among the first complex societies in Europe. Its economy was based on cereal cultivation and metallurgy, it was organized hierarchically, and successively expanded its territory. Most of the monumentally fortified settlements lay on steeply sloped mountains, separated by fertile plains, and allowed optimal control of the area. Here, we explore El Argar human diets, animal husbandry strategies, and food webs using stable carbon and nitrogen isotope analysis of charred cereal grains as well as human and animal bone collagen. The sample comprised 75 human individuals from the sites of La Ba…
The role of fire within Neolithic collective burials: Spatial analyses of cremains from the site of La Truie Pendue, France
2016
International audience; The use of collective graves is one of the main features of the western European Late Neolithic. A single gravesite received the successive deposition of dozens or sometimes hundreds of individuals. While cremations or even full-fired inhumation layers are often found within these funerary deposits, the actual role of fire is still poorly understood. Recently discovered within the important archaeological complex of Passy (Yonne, France), the burned collective grave of La Truie-Pendue provides an outstanding case study to examine the use of fire within Neolithic funerary rites. In this study, we develop a new contextual approach to bone alterations in order to recons…
Life after death: a physicochemical study of materials used by the ancient Maya in human bone ointments
2021
Ancient Maya believed in life after death. They used to prepare dead bodies during burial ceremonies whose purpose was to celebrate the dead and to help them passing through the way from earthly life to the beyond one. Bodies preparation included coloured scented body ointment application, with a deep symbolic connotation and probably also a conservative purpose. The aim of this research was to characterize pigments and binders used by ancient Maya in the preparation of body oint ments used to paint human bones. Emblematic painted bone samples from Xcambó (Maya archaeological site located in the municipality of Dzemul, in the Mexican state of Yucatán) were investigated through a non-destruc…
A refugee newborn with heart failure and initial hydrops: Diagnostic clues of spectral Doppler examinations
2022
A newnborn admitted to NICU showed a severe clinical profile
Cone-beam computed tomography and its applications in dental and maxillofacial radiology.
2020
Cone-beam computed tomography (CBCT) was first used in dental and maxillofacial radiology (DMFR) at the end of the 1990s. Since then, it has been successfully established as the standard three-dimensional radiographic imaging technique in DMFR, with a wide variety of applications in this field. This manuscript briefly reviews the background information on the technology and summarises available data on effective dose and dose optimisation. In addition, typical clinical applications and indications of the technique in DMFR are presented.
Bone Scaffolds Based on Degradable Vaterite/PEG‐Composite Microgels
2019
Vaterite, a metastable modification of calcium carbonate, embedded in a flexible microgel packaging with adjustable mechanical properties, functionality, and biocompatibility, provides a powerful scaffolding for bone tissue regeneration, as it is easily convertible to bone-like hydroxyapatite (HA). In this study, the synthesis and physical analysis of a packaging material to encapsulate vaterite particles and osteoblast cells into monodisperse, sub-millimeter-sized microgels, is described whereby a systematic approach is used to tailor the microgel properties. The size and shape of the microgels is controlled via droplet-based microfluidics. Key requirements for the polymer system, such as …
Towards the development of a fossil bone geochemical standard: An inter-laboratory study
2007
Ten international laboratories participated in an inter-laboratory comparison of a fossil bone composite with the objective of producing a matrix and structure-matched reference material for studies of the bio-mineralization of ancient fossil bone. We report the major and trace element compositions of the fossil bone composite, using in-situ method as well as various wet chemical digestion techniques. For major element concentrations, the intra-laboratory analytical precision (%RSDr) ranges from 7 to 18%, with higher percentages for Ti and K. The %RSDr are smaller than the inter-laboratory analytical precision (%RSDR; 100% was found for the high field strength elements (Hf, Th, Zr, Nb). The…
Specific expression of a TRIM-containing factor in ectoderm cells affects the skeletal morphogenetic program of the sea urchin embryo
2011
In the indirect developing sea urchin embryo, the primary mesenchyme cells (PMCs) acquire most of the positional and temporal information from the overlying ectoderm for skeletal initiation and growth. In this study, we characterize the function of the novel gene strim1, which encodes a tripartite motif-containing (TRIM) protein, that adds to the list of genes constituting the epithelial-mesenchymal signaling network. We report that strim1 is expressed in ectoderm regions adjacent to the bilateral clusters of PMCs and that its misexpression leads to severe skeletal abnormalities. Reciprocally, knock down of strim1 function abrogates PMC positioning and blocks skeletogenesis. Blastomere tran…
Bone status in adolescents with type 1 diabetes
2010
Aims The aim of the study was to investigate the potential negative impact of type 1 diabetes on bone status of adolescents. Bone status in adolescents with type 1 diabetes was assessed by means of quantitative ultrasound (QUS) and the influence of metabolic control and other diseaserelated and growth variables was analysed. Methods Group I consisted of 99 pubertal (Tanner ≥2) adolescents (49 female), aged 14.3±2.5 years, diabetes duration 4.6±2.3 years. Controls (group II) were 297 children, matched by sex and age, from a healthy population. The influence of glycated haemoglobin (current: HbA1cD; last year’s mean: HbA1cY; whole duration mean: HbA1cT), diabetes duration, percentage of life …