Search results for "boron"

showing 10 items of 352 documents

Bortezomib induces in HepG2 cells IkappaBalpha degradation mediated by caspase-8.

2006

The present paper demonstrates that the proteasome inhibitor bortezomib, which behaves as an apoptotic agent in hepatoma HepG2 cells, caused in these cells a decrease in IkappaBalpha level and a consequent increase in NF- kappaB activity. The effect already appeared at 4 h of treatment and preceded the onset of apoptosis which was observed at 24 h. Our results demonstrate that bortezomib-induced IkappaBalpha degradation occurred in conjunction with the activation of caspase-8; moreover, the decrease in IkappaBalpha level was prevented in a dose-dependent manner by the addition of z-IETD, a specific inhibitor of caspase-8. Bortezomib caused the same effects in non-tumor Chang liver cells, wh…

Clinical BiochemistryBiologyCaspase 8Cell LineBortezomibchemistry.chemical_compoundNF-KappaB Inhibitor alphaCell Line Tumormedicinehepatoblastoma proteasome inhibitors NF-kB apoptosisHumansMolecular BiologyCaspase 8BortezomibLiver NeoplasmsNF-kappa BNF-κBCalpainCell BiologyGeneral MedicineMolecular biologyBoronic AcidsIκBαchemistryLiverApoptosisCell culturePyrazinesCancer researchProteasome inhibitorbiology.proteinI-kappa B Proteinsmedicine.drug
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First-principles calculations on double-walled inorganic nanotubes with hexagonal chiralities

2011

The two sets of commensurate double-walled boron nitride and titania hexagonally-structured nanotubes (DW BN and TiO2 NTs) possessing either armchair- or zigzag-type chiralities have been considered, i.e., (n1,n1)@(n2,n2) or (n1,0)@(n2,0), respectively. For symmetry analysis of these nanotubes, the line symmetry groups for one-periodic (1D) nanostructures with rotohelical symmetry have been applied. To analyze the structural and electronic properties of hexagonal DW NTs, a series of large-scale ab initio DFT-LCAO calculations have been performed using the hybrid Hartree-Fock/Kohn-Sham exchange-correlation functional PBE0 (as implemented in CRYSTAL-09 code). To establish the optimal inter-sh…

Condensed Matter::Materials Sciencechemistry.chemical_compoundReflection symmetryNanostructureDouble walledCondensed matter physicsChemistryBoron nitrideHexagonal crystal systemPhysics::Atomic and Molecular ClustersAb initioTotal energySymmetry (physics)IOP Conference Series: Materials Science and Engineering
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Synthesis of quadruped-shaped polyfunctionalized o-carborane synthons

2011

[EN] o-Carborane derivatives with precisely defined patterns of substitution have been prepared from 8,9,10,12-I-4-1,2-closo-C2B10H8 by replacing the iodine atoms, bonded to four adjacent boron vertices in the cluster, with allyl, and subsequently 3-hydroxypropyl groups. The resulting structures, comprising four pendant arms and two reactive vertices located on opposite sides of a central o-carborane core, can be envisaged as versatile precursors for dendritic growth

DendrimersIcosahedral CarboranesStereochemistryMolecular ConformationNeutron-Capture TherapySupramolecular Assemblieschemistry.chemical_elementBoranesCrystallography X-Ray010402 general chemistry01 natural sciencesCatalysisMolecular conformationDendrimerQUIMICA ANALITICAMaterials ChemistryCluster (physics)BoranesBoronta116CancerIodination010405 organic chemistryChemistryPolysubstituted FrameworksSynthonMetals and AlloysHalogenationGeneral Chemistry3. Good health0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsC-HChemistryCrystallographyCeramics and CompositesCarboraneDerivativesIodineChemical Communications
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Ferromagnetic Coupling between Low- and High-Spin Iron(III) Ions in the Tetranuclear Complex fac-{[FeIII{HB(pz)3}(CN)2(μ-CN)]3FeIII(H2O)3}· 6H2O ([HB…

2002

The novel mononuclear PPh4-fac-[FeIII{HB(pz)3}(CN)3]·H2O (1) [PPh4+= tetraphenylphosphonium cation; (HB(pz)3)- = hydrotris(1-pyrazolyl)borate] and tetranuclear fac-{[FeIII{HB(pz)3}(CN)2(μ-CN)]3FeIII(H2O)3}·6H2O (2) have been prepared and characterized by X-ray diffraction analysis. Crystal data for compound 1:  monoclinic, space group P21/c, a = 9.575(3) A, b = 21.984(4) A, c = 16.863(3) A, β = 100.34(2)°, U = 3486(1) A3, Z = 4. Crystal data for compound 2:  orthorhombic, space group Pnam, a = 14.084(3) A, b = 14.799(4) A, c = 25.725(5) A, U = 5362(2) A3, Z = 4. Compound 1 is a low-spin iron(III) compound with three cyanide ligands in fac arrangement and a tridentate pyrazolylborate ligand …

DenticityChemistryStereochemistryLigandCyanidechemistry.chemical_elementIonInorganic ChemistryCrystallographychemistry.chemical_compoundOctahedronOrthorhombic crystal systemPhysical and Theoretical ChemistryBoronMonoclinic crystal systemInorganic Chemistry
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Flow injection spectrophotometric determination of boron in ceramic materials.

1998

Abstract A flow injection spectrophotometric method for the determination of boron in ceramic materials is described. The method is based on spectrophotometric measurement of the decrease in the pH produced by the reaction between boric acid and mannitol in the presence of an acid-base indicator. A bichannel FI (flow injection) manifold in which the sample solutions were injected into deionized water (at pH 5.4) and the stream was later merged with the reagent stream (a mannitol solution containing 1×10 −4 mol l −1 bromocresol green at pH 5.4), was used. Transient signals were monitored at 616 nm. A theoretical model which describes the dependence between the absorbance values and boric aci…

Detection limitBromocresol greenmedicine.diagnostic_testPotentiometric titrationAnalytical chemistrychemistry.chemical_elementCeramic materialsAnalytical ChemistryBoric acidAbsorbancechemistry.chemical_compoundchemistrySpectrophotometryReagentmedicineBoronTalanta
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Identification of ground water contaminations by landfills using precise boron isotope ratio measurements with negative thermal ionization mass spect…

1997

Precise boron isotope ratio measurements with negative thermal ionization mass spectrometry were used for the identification of ground water contaminations by leakages of landfills. BO 2 - thermal ions were produced to determine the 11 B/ 10 B isotope ratio, which was expressed as δ 11 B value in ‰ normalized to the standard reference material NIST SRM 951. For example, household waste influences the boron isotope ratio by specific components such as washing powder. In the case of one investigated landfill low δ 11 B values correlate well with high boron concentrations in contaminated seepage water samples and vice versa for uncontaminated ground water samples. Possible boron contributions …

Detection limitchemistryIsotopeAnalytical chemistrychemistry.chemical_elementThermal ionizationIsotopes of boronIsotope dilutionThermal ionization mass spectrometryBoronMass spectrometryBiochemistryFresenius' Journal of Analytical Chemistry
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Spark source mass spectrometric assessment of boron and nitrogen concentrations in crystalline gallium arsenide

1999

The residual or doped element concentration [E] in GaAs measured by SSMS is only accurate with respect to the relative sensitivity coefficient RSCE. For a trace element concentration, the RSCE = [E]SSMS/[E]TRUE is set to unity, if no reference material or method is available to approximate the concentration to the true value. For boron a relative sensitivity coefficient of RSCB = 0.94 ± 0.08 was obtained using TI-IDMS as a reference method. RSCN = 1 is used for nitrogen determinations. A boron and nitrogen detection limit of 4.4 × 1013 cm–3 is achieved. SSMS was used as reference method to calibrate the FTIR factor fE = [E] / Iα due to the integrated local vibrational mode absorption Iα of …

Detection limitchemistry.chemical_compoundchemistryDopingAnalytical chemistrychemistry.chemical_elementInfrared spectroscopyMass spectrometryBoronBiochemistryNitrogenGallium arsenideBOROFresenius' Journal of Analytical Chemistry
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Boron-Doped Diamond Electrodes for Electroorganic Chemistry

2011

Boron-doped diamond (BDD) electrodes provide an unusually wide electrochemical window in protic media, since there exist large offset potentials for the evolution of molecular hydrogen and oxygen, respectively. At the anode, alcohols are specifically converted to alkoxyl radicals. These can be used for chemical synthesis. When the enormous reactivity of such intermediate spin centers is not controlled, mineralization or electrochemical incineration dominates. Efficient strategies include either high substrate concentrations or fluorinated alcohols which seem to stabilize the spin centers in the course of reaction.

Diamondchemistry.chemical_elementengineering.materialElectrosynthesisPhotochemistryElectrochemistryCathodelaw.inventionAnodechemistrylawElectrodeengineeringBoronElectrochemical window
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Compressibility Systematics of Calcite-Type Borates: An Experimental and Theoretical Structural Study on ABO(3) (A = Al, Sc, Fe, and In)

2014

The structural properties of calcite-type orthoborates ABO(3) (A = Al, Fe, Sc, and In) have been investigated at high pressures up to 32 GPa. They were studied experimentally using synchrotron powder X-ray diffraction and theoretically by means of ab initio total-energy calculations. We found that the calcite-type structure remains stable up to the highest pressure explored in the four studied compounds. Experimental and calculated static geometries (unit-cell parameters and internal coordinates), bulk moduli, and their pressure derivatives are in good agreement. The compressibility along the c axis is roughly three times that along the a axis. Our data clearly indicate that the compressibi…

DiffractionAb initioThermodynamicschemistry.chemical_elementCrystal structureHigh-pressure behaviorchemistry.chemical_compoundstructure carbonatesCationshigh pressure behavior; augmented-wave method; structure carbonatesPhysical and Theoretical ChemistryBoronCalciteCrystal-structuresMetal refinementOxidesFeBO3Surfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCrystallographyGeneral Energyhigh pressure behaviorchemistryOctahedronAugmented-wave methodFISICA APLICADATransitionCompressibilityaugmented-wave methodCarbonateStructure carbonates
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Discovery of new boron-rich chalcogenides: Orthorhombic B6X (X=S, Se)

2020

The authors thank T. Chauveau (LSPM) for help with Rietveld analysis, A. Jamali (LRCS) for assistance with SEM measurements, and Drs. Y. Tange (SPring-8) and N. Guignot (SOLEIL) for help in synchrotron experiments that were carried out during beamtimes allocated to proposals 2017A1047 & 2018A1121 at SPring-8 and proposal 20170092 at SOLEIL. Ab initio calculations have been performed using Rurik and Arkuda supercomputers. This work was financially supported by the European Union’s Horizon 2020 Research and Innovation Programme under Flintstone2020 project (grant agreement No. 689279). Z.W. thanks the National Science Foundation of China (grant No. 11604159). A.R.O. thanks the Russian Ministr…

DiffractionMaterials sciencePhononlcsh:MedicineFOS: Physical sciences02 engineering and technology[CHIM.INOR]Chemical Sciences/Inorganic chemistry01 natural scienceschemistry.chemical_compoundsymbols.namesakeCondensed Matter::Materials ScienceAb initio quantum chemistry methodsSelenideCondensed Matter::Superconductivity0103 physical sciences[CHIM.CRIS]Chemical Sciences/Cristallographylcsh:Science010302 applied physicsCondensed Matter - Materials ScienceMultidisciplinaryRietveld refinementlcsh:RMaterials Science (cond-mat.mtrl-sci):NATURAL SCIENCES::Physics [Research Subject Categories][CHIM.MATE]Chemical Sciences/Material chemistry021001 nanoscience & nanotechnologyAmorphizationCrystal structure predictionBoron CarbideCrystallographychemistrysymbolslcsh:QOrthorhombic crystal systemNeutron Absorber0210 nano-technologyRaman spectroscopyScientific Reports
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