Search results for "càncer"

showing 10 items of 150 documents

Measurement of body composition in cancer patients using CT planning scan at the third lumbar vertebra

2019

Objective: the main objective was to assess body composition in terms of skeletal muscle index (SMI), myosteatosis, visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and intermuscular adipose tissue (IMAT) as an adjunct of information provided by radiotherapy CT planning scan. Material and methods: a sample of 49 patients with lung and digestive cancers underwent a CT scan for radiotherapy treatment, which included measurements at the L3 region. Images were analyzed with a radiotherapy contouring software, using different Hounsfield Unit (HU) settings. Cross-sectional areas (cm2) were automatically computed by summing tissue pixels and multiplying by pixel surface area. Low …

AdultMale0301 basic medicineCT scanLung NeoplasmsRadioteràpiaMedicine (miscellaneous)030209 endocrinology & metabolismComputed tomographyDigestive System NeoplasmsBody composition03 medical and health sciences0302 clinical medicineHounsfield scalemedicineHumansAgedRetrospective StudiesCancerAged 80 and overThird lumbar vertebraLumbar Vertebrae030109 nutrition & dieteticsNutrition and DieteticsCt planningmedicine.diagnostic_testRadiotherapybusiness.industryRadiotherapy Planning Computer-AssistedCancerMiddle Agedmedicine.diseaseHighly sensitiveBody CompositionFemaleRadiotherapy treatmentSubcutaneous adipose tissueTomography X-Ray ComputedCàncer PacientsNuclear medicinebusiness
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Diagnosis of pre-sarcopenia from a single selectional crosscut at C3 region, using CT scans before radiotherapy

2019

espanolProposito: el proposito de este estudio fue diagnosticar la presarcopenia en pacientes con cancer que no disponen de imagenes por tomografia computarizada (TC) a nivel abdominal mediante un metodo novedoso basado en cortes a nivel cervical. Material y metodos: se analizaron y se compararon mediante unidades la masa muscular y la masa muscular esqueletica en 37 pacientes con cancer de pulmon y neoplasias del aparato digestivo superior que incluian cortes en la TC de planificacion a nivel de C3 y L3. La presarcopenia se identifico de acuerdo con los puntos de corte establecidos actualmente: ≤ 41 cm2/m2 para mujeres, ≤ 43 cm2/m2 en hombres con un IMC ≤ 25 kg/m2 y ≤ 53 cm2/m2 en hombres …

AdultMale0301 basic medicineSarcopeniaLung NeoplasmsEsophageal Neoplasmsmedicine.medical_treatmentTomografiaMedicine (miscellaneous)Radioteràpia030209 endocrinology & metabolismComputed tomographyCohort Studies03 medical and health sciences0302 clinical medicineStomach NeoplasmsmedicineHumansC3Lung cancerCàncerCancerAgedRetrospective StudiesAged 80 and over030109 nutrition & dieteticsNutrition and DieteticsRadiotherapymedicine.diagnostic_testbusiness.industryMiddle Agedmedicine.diseaseSkeletal muscle massPancreatic NeoplasmsRadiation therapyL3SarcopeniaCT scansFemaleRadiotherapy treatmentTomography X-Ray ComputedbusinessNuclear medicine
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Relationship between oral cancer and implants : clinical cases and systematic literature review

2010

Podeu consultar la versió en castellà a http://hdl.handle.net/2445/135800

AdultMaleMEDLINEDentistryMalalties de la bocaOsseointegrationCarcinomaMedicineHumansRisk factorCàncerGeneral DentistryAgedCancerMouth neoplasmDental ImplantsOral Medicine and PathologyImplants dentalsbusiness.industryDental implantsReview-ArticleCancermedicine.disease:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesSystematic reviewMouth diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgeryMouth NeoplasmsImplantbusiness
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S-100 protein positive cells in nasopharyngeal carcinoma (NPC): absence of prognostic significance. A clinicopathological and immunohistochemical stu…

1987

An immunohistochemical study of S-100 protein in 43 nasopharyngeal carcinomas (NPC) of known clinical evolution (33 primary and 10 metastatic) is presented. Sixty per cent of primary site cases as well as all metastatic forms showed S-100 protein positive cells intermingled with tumour cells. These S-100 positive elements were identified as Langerhans cells. No significant differences were found when correlating S-100 protein positivity and histological NPC variants, neither in age nor in sex of patients. Statistical analysis failed to demonstrate any positive correlation between S-100 protein reactivity and clinical survival.

AdultMalePathologymedicine.medical_specialtyAdolescentNasopharyngeal neoplasmTumor cellsPositive correlationPathology and Forensic MedicinemedicineHumansStatistical analysisChildCàncerMolecular Biologybusiness.industryS100 ProteinsNas MalaltiesNasopharyngeal NeoplasmsCell BiologyGeneral MedicineMiddle Agedmedicine.diseasePrognosisNeoplasm ProteinsNasopharyngeal carcinomaImmunologic TechniquesImmunohistochemistryFemalebusiness
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Central odontogenic fibroma: retrospective study of 8 clinical cases

2010

Introduction and Objectives: The central odontogenic fibroma (COF) is a benign odontogenic tumour derived from the dental mesenchymal tissues. It is a rare tumour and only 70 cases of it have been published. Bearing in mind the rareness of the tumour, 8 new cases of central odontogenic fibroma have been found by analyzing the clinical, radiological and histopathological characteristics of COF. Patients and Method: A retrospective study was carried out on 3011 biopsies in the Service of Oral and Maxillofacial Surgery of the Dental Clinic of Barcelona University between January 1995 and March 2008. 85 odontogenic tumours were diagnosed of which 8 were central odontogenic fibroma. The radiolog…

AdultMalemedicine.medical_specialtyAdolescentDentistryOdontogenic TumorsJawsFibromaJaw neoplasmLesionYoung AdultCentral odontogenic fibromaMedicineHumansChildCàncerGeneral DentistryRetrospective StudiesTumorsCancerOral Medicine and PathologyMaxil·larsbusiness.industryMandibleRetrospective cohort studyFibromasmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Jaw NeoplasmsFibromesstomatognathic diseasesOtorhinolaryngologyRadiological weaponUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgerySurgeryFemaleResearch-ArticleRadiologymedicine.symptomFibromabusiness
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Incidence rate of metastases in the oral cavity: a review of all metastatic lesions in the oral cavity

2021

Background Metastases in the oral cavity are rare and account for only 1 to 3% of all malignant lesions in this area. The primary location from which most metastases have been described in the oral cavity in adult patients include lungs, breasts, kidneys and colon. Material and Methods A systematic search of the literature was carried out following the PRISMA statement in PubMed database. Clinical trials and case series published in the last 10 years [2010-2020] were eligible to be selected. The headings and keywords used in the searches were “cancer” AND “oral metastases”, “incidence” AND “oral metastases”, “oral metastases” AND “jaw bone”, “oral metastases” AND “soft tissue”. Results For …

AdultMalepleomorphic adenomamedicine.medical_specialtyReviewMetastasisMetàstasiProstateOral Cancer and Potentially malignant disorderssublingual glandHumansMedicineadenoid cystic carcinomaGeneral DentistryUNESCO:CIENCIAS MÉDICASRetrospective Studiesbusiness.industryOral cancerIncidenceIncidence (epidemiology)ThyroidSoft tissueCancerRetrospective cohort studymedicine.diseasePrimary tumorCàncer de bocamucoepidermoid carcinomaClinical trialsalivary gland neoplasmsmedicine.anatomical_structureJawOtorhinolaryngologyMouth NeoplasmsSurgeryRadiologybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer

2019

Este es el artículo que se ha publicado de forma definitiva en: https://molecularautism.biomedcentral.com/articles/10.1186/s13229-019-0262-8 En este artículo también participa Joan Climent, Vera Pancaldi, Lourdes Fañanás, Celso Arango, Mara Parellada, Anaïs Baudot, Daniel Vogt, John L. Rubenstein, Alfonso Valencia y Rafael Tabarés-Seisdedos. Background: Epidemiological and clinical evidence points to cancer as a comorbidity in people with autism spectrum disorders (ASD). A significant overlap of genes and biological processes between both diseases has also been reported. Methods: Here, for the first time, we compared the gene expression profiles of ASD frontal cortex tissues and 22 cancer t…

Autism.AutismComorbidityBioinformaticsAutismo.lcsh:RC346-429Expresión génica.TranscriptomeAfectividad - Trastornos.0302 clinical medicineNeoplasmsGene expression2.1 Biological and endogenous factorsAetiologyCàncerCáncer - Aspectos genéticos.ComputingMilieux_MISCELLANEOUSCancer0303 health sciencesProstate CancerBrainAffective disorders.3. Good healthPsychiatry and Mental healthMental HealthSignal transductionSignal TransductionBiotechnologyUrologic DiseasesIntellectual and Developmental Disabilities (IDD)1.1 Normal biological development and functioningClinical SciencesBiologyASDBiological pathway03 medical and health sciencesDevelopmental NeuroscienceUnderpinning researchmental disordersGeneticsmedicineHumansAutistic DisorderIntellectual and Developmental DisabilitiesGeneMolecular Biologylcsh:Neurology. Diseases of the nervous systemPI3K/AKT/mTOR pathwayCancer - Genetic aspects.030304 developmental biologyResearchNeurosciencesMultimorbidityCancermedicine.diseaseExpressió gènicaHuman geneticsBrain DisordersMeta-analysisGene expression.AutismGene expressionAutisme[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]TranscriptomeKidney cancer030217 neurology & neurosurgeryDevelopmental BiologyMolecular Autism
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Allogeneic Stem Cell Transplantation in Mantle Cell Lymphoma; Insights into Its Potential Role in the Era of New Immunotherapeutic and Targeted Thera…

2022

Simple Summary We present the long-term results of patients receiving allogeneic stem cell transplantation (allo-SCT) for relapsed/refractory mantle cell lymphoma (R/R MCL) in the last 25 years in Spain. We conclude that allo-SCT may be a curative option in R/R MCL with a low cumulative incidence (CI) of relapse, although non-relapse mortality (NRM) is still high, which is mainly secondary to acute graft-versus-host disease (aGVHD). Results are better for fit patients, using HLA-identical (related or unrelated) or haploidentical related donors and without previous ASCT. However, the arrival of new highly effective and low toxic immunotherapeutic or targeted therapies inevitably will relegat…

CAR-T cell therapyCancer ResearchLimfomesMantle cell lymphomaAcute graft-versus-host diseaseTransplantation of organstarget therapyacute graft-versus-host diseasemantle cell lymphomaTarget therapyTrasplantament d'òrgansgraft-versus-lymphoma effectnon-relapse mortalityOncologyNon-relapse mortalityimmune system diseaseshemic and lymphatic diseasesallogeneic stem-cell transplantationmantle cell lymphoma; allogeneic stem-cell transplantation; non-relapse mortality; acute graft-versus-host disease; graft-versus-lymphoma effect; target therapy; CAR-T cell therapyLymphomasAllogeneic stem-cell transplantationCàncerGraft-versus-lymphoma effect
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Determination of essential biomarkers in lung cancer: a real-world data study in Spain with demographic, clinical, epidemiological and pathological c…

2022

Abstract Background The survival of patients with lung cancer has substantially increased in the last decade by about 15%. This increase is, basically, due to targeted therapies available for advanced stages and the emergence of immunotherapy itself. This work aims to study the situation of biomarker testing in Spain. Patients and methods The Thoracic Tumours Registry (TTR) is an observational, prospective, registry-based study that included patients diagnosed with lung cancer and other thoracic tumours, from September 2016 to 2020. This TTR study was sponsored by the Spanish Lung Cancer Group (GECP) Foundation, an independent, scientific, multidisciplinary oncology society that coordinates…

Cancer Research:Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms [DISEASES]Lung NeoplasmsTesting:Biological Factors::Biomarkers [CHEMICALS AND DRUGS]:factores biológicos::biomarcadores [COMPUESTOS QUÍMICOS Y DROGAS]Targeted therapiesPulmons - Càncer:neoplasias::neoplasias por localización::neoplasias torácicas::neoplasias del tracto respiratorio::neoplasias pulmonares [ENFERMEDADES]Carcinoma Non-Small-Cell LungProto-Oncogene ProteinsGeneticsBiomarkers TumorHumansProspective StudiesCàncerDemographyReceptor Protein-Tyrosine KinasesProtein-Tyrosine KinasesErbB ReceptorsOncologySpainPulmonsMarcadors bioquímicsBiomarkersMetastatic lung cancer
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The “unnatural” history of colorectal cancer in Lynch syndrome : lessons from colonoscopy surveillance

2021

Individuals with Lynch syndrome (LS), one of the most common inherited cancer syndromes, are at increased risk of developing malignancies, in particular colorectal cancer (CRC). Regular colonoscopy with polypectomy is recommended to reduce CRC risk in LS individuals. However, recent independent studies demonstrated that a substantial proportion of LS individuals develop CRC despite regular colonoscopy. The reasons for this surprising observation confirmed by large prospective studies are a matter of debate. In this review, we collect existing evidence from clinical, epidemiological and molecular studies and interpret them with regard to the origins and progression of LS-associated CRC. Alon…

Cancer ResearchColorectal cancermedicine.medical_treatmentColonoscopyDNA Mismatch RepairADENOMA DETECTION0302 clinical medicineRisk FactorsEpidemiologyMass ScreeningProspective cohort studyMUTATIONRISKmedicine.diagnostic_testincident cancer riskColonoscopyTUMORSLynch syndrome3. Good healthOncology030220 oncology & carcinogenesisPopulation SurveillancesyöpätauditColorectal Neoplasmskoloskopiamedicine.medical_specialtyLONG-TERM3122 Cancerscolorectal cancersuolistosyövätINTERVAL CANCERS03 medical and health sciencesINTESTINAL MICROBIOTACàncer colorectalCOLONmedicineMANAGEMENTHumansLynchin oireyhtymäIntensive care medicinepaksusuolisyöpäperinnölliset tauditseulontatutkimusbusiness.industrymismatch repair deficiencyMicrosatellite instabilityCancerColonoscòpiamedicine.diseaseColorectal Neoplasms Hereditary NonpolyposisPolypectomydigestive system diseasesDNA Repair EnzymesLynch syndromemicrosatellite instabilitybusinesscolonoscopy surveillance
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