Search results for "cART"
showing 10 items of 2010 documents
Sequential Monte Carlo methods in Bayesian joint models for longitudinal and time-to-event data
2020
The statistical analysis of the information generated by medical follow-up is a very important challenge in the field of personalized medicine. As the evolutionary course of a patient's disease progresses, his/her medical follow-up generates more and more information that should be processed immediately in order to review and update his/her prognosis and treatment. Hence, we focus on this update process through sequential inference methods for joint models of longitudinal and time-to-event data from a Bayesian perspective. More specifically, we propose the use of sequential Monte Carlo (SMC) methods for static parameter joint models with the intention of reducing computational time in each…
Temporal evolution of some mortality indicators: Application to Spanish data
2012
[EN] In Spain, as in other developed countries, significant changes in mortality patterns have occurred during the 20th and 21st centuries. One reflection of these changes is life expectancy, which has improved in this period, although the robustness of this indicator prevents these changes from being of the same order as those for the probability of death. If, moreover, we bear in mind that life expectancy offers no information as to whether this improvement is the same for different age groups, it is important and necessary to turn to other mortality indicators whose past and future evolution in Spain we are going to study. These indicators are applied to Spanish mortality data for the pe…
Modelling residuals dependence in dynamic life tables: A geostatistical approach
2008
The problem of modelling dynamic mortality tables is considered. In this context, the influence of age on data graduation needs to be properly assessed through a dynamic model, as mortality progresses over the years. After detrending the raw data, the residuals dependence structure is analysed, by considering them as a realisation of a homogeneous Gaussian random field defined on R × R. This setting allows for the implementation of geostatistical techniques for the estimation of the dependence and further interpolation in the domain of interest. In particular, a complex form of interaction between age and time is considered, by taking into account a zonally anisotropic component embedded in…
Probabilistic small area risk assessment using GIS-based data: a case study on Finnish childhood diabetes
2000
A Bayesian hierarchical spatial model is constructed to describe the regional incidence of insulin dependent diabetes mellitus (IDDM) among the under 15-year-olds in Finland. The model exploits aggregated pixel-wise locations for both the cases and the population at risk. Typically such data arise from combining geographic information systems (GIS) with large databases. The dates of diagnosis and locations of the cases are observed from 1987 to 1996. The population at risk counts are available for every second year during the same period. A hierarchical model is suggested for the pixel wise case counts, including a population model to account for the uncertainty of the population at risk ov…
Il monitoraggio topografico della cattedrale di Agrigento con metodi tradizionali
2014
L’oggetto del presente lavoro è il monitoraggio della cattedrale di San Gerlando di Agrigento, duomo eretto tra i secoli XI e XII, che sorge nella parte più alta della collina di Girgenti. Lo studio è significativo poiché, nel corso dei secoli la costruzione è stata soggetta a interventi di ristrutturazione e di consolidamento, resi necessari dai danni arrecati da frane che, in più occasioni, hanno coinvolto il territorio su cui essa sorge. Dal 2010 la chiesa è chiusa al culto per copiosi eventi franosi e idrogeologici che hanno allarmato ulteriormente anche la Protezione Civile. A seguito di questi eventi è stata avviata una campagna di indagini e monitoraggi con il fine della caratterizza…
Bioactive pyrrole alkaloids isolated from the Red Sea : marine sponge Stylissa carteri
2017
Abstract Fifteen pyrrole alkaloids were isolated from the Red Sea marine sponge Stylissa carteri and investigated for their biological activities. Four of them were dibrominated [(+) dibromophakelline, Z-3-bromohymenialdisine, (±) ageliferin and 3,4-dibromo-1H-pyrrole-2-carbamide], nine compounds were monobrominated [(−) clathramide C, agelongine, (+) manzacidin A, (−) 3-bromomanzacidin D, Z-spongiacidin D, Z-hymenialdisine, 2-debromostevensine, 2-bromoaldisine and 4-bromo-1H-pyrrole-2-carbamide)] and finally, two compounds were non-brominated derivatives viz., E-debromohymenialdisine and aldisine. The structure elucidations of isolated compounds were based on 1D & 2D NMR spectroscopic …
Diffusion of ionic and non-ionic contrast agents in articular cartilage with increased cross-linking--contribution of steric and electrostatic effect…
2013
Abstract Objective To investigate the effect of threose-induced collagen cross-linking on diffusion of ionic and non-ionic contrast agents in articular cartilage. Design Osteochondral plugs (O=6mm) were prepared from bovine patellae and divided into two groups according to the contrast agent to be used in contrast enhanced computed tomography (CECT) imaging: (I) anionic ioxaglate and (II) non-ionic iodixanol. The groups I and II contained 7 and 6 sample pairs, respectively. One of the paired samples served as a reference while the other was treated with threose to induce collagen cross-linking. The equilibrium partitioning of the contrast agents was imaged after 24h of immersion. Fixed char…
Los signos de la grandeza urbana: el Civitates Orbis Terrarum
2011
Los seis tomos del Civitates Orbis Terrarum, resultado de la labor infatigable de Georg Braun, Franz Hogenberg y de sus colaboradores, sobre todo del pintor Georg (o Joris) Hoefnagel, constituyen un instrumento inigualable para el estudio de la historia de los asentamientos y, más en general, para la comprensión del fenómeno urbano en Europa en la primera edad moderna. Son múltiples los temas sobre los que nos induce a reflexionar el análisis de la valiosa y heterogénea recopilación de plantas y vistas a vuelo de pájaro: la forma urbis, la construcción de apariencias urbanas representativas, la inserción de la ciudad en el paisaje, su relación con el territorio, la singularidad de las técni…
Un raffinato studio sulle carte aragonesi del Regno di Napoli
2009
"A refined essay on Aragonese Maps of the Kingdom of Naples" ,starts from the rewiew of a research of V.Valerio and F.La Greca to outline some hypotesis on the excellent topographical maps produced during the Aragonese period of the Kingdom af Naples
Descates and the "impossible" constructions with ruler and compass
2009
Si descrivono i tentativi di Descartes di determinare quando un problema geometrico e' risolubile con riga e compasso