Search results for "cMRgFUS"

showing 10 items of 16 documents

TRANS-CRANIAL MRI-GUIDED FOCUSED ULTRASOUND SURGERY (TCMRGFUS): ITALIAN AND WORLD-FIRST EXPERIENCE AT 1.5 TESLA

2016

Introduction: Transcranial magnetic resonance-guided focused ultrasound surgery (tcMRgFUS) is a promising new technology for the noninvasive treatment of various brain disorders. Here, we present our preliminary results achieved with the first Italian installation of a transcranial MRI-guided focused ultrasound surgery (tcMRgFUS) certified system for functional neurosurgery. Technical issues faced to achieve a safe and effective treatment will be discussed focusing on MR high-resolution live imaging and thermometry sequences optimization. Materials and Methods: Patient enrollment was based on indication for functional neurosurgery and evidence of medication-refractory disease; a detailed me…

Engineeringbusiness.industryTCMRGFUS MRI MDCTBiophysicsGeneral Physics and AstronomySettore MED/37 - NeuroradiologiaGeneral MedicineFocused ultrasound surgerySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Radiology Nuclear Medicine and imagingNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaMri guided
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Preliminary experience with a transcranial magnetic resonance-guided focused ultrasound surgery system integrated with a 1.5-T MRI unit in a series o…

2018

OBJECTIVETranscranial magnetic resonance–guided focused ultrasound surgery (tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of neurological disorders such as essential tremor (ET), idiopathic asymmetrical tremor-dominant Parkinson’s disease (PD), and neuropathic pain. In this clinical series the authors present the preliminary results achieved with the world’s first tcMRgFUS system integrated with a 1.5-T MRI unit.METHODSThe authors describe the results of tcMRgFUS in a sample of patients with ET and with PD who underwent the procedure during the period from January 2015 to September 2017. A monolateral ventralis intermedius nucleus (VIM) thalamic ablation was pe…

MaleParkinson's diseaseMovement disordershigh-intensity focused ultrasound ablationIntraoperative Neurophysiological Monitoringmedicine.medical_treatmentinterventional030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery0302 clinical medicineThalamusEssential tremorSettore MED/27 - NeurochirurgiaUltrasoundSettore MED/37 - NeuroradiologiaParkinson DiseaseGeneral MedicineMiddle AgedAblationMagnetic Resonance ImagingTreatment OutcomeNeuropathic painBBB = blood-brain barrier; ET = essential tremor; FRFSE = fast recalled FSE; FSE = fast spin echo; FSPGR = fast spoiled gradient echo; FTM = Fahn-Tolosa-Marin; HI-FU = high-intensity focused ultrasound; MRI; MRgFUS; MS = multiple sclerosis; PD = Parkinson’s disease; Parkinson’s disease; QUEST = Quality of Life in Essential Tremor; SWAN = susceptibility-weighted angiography; UPDRS = Unified Parkinson’s Disease Rating Scale; VIM = ventralis intermedius nucleus; brain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance–guided focused ultrasound surgery; stereotactic technique; tcMRgFUS = transcranial magnetic resonance–guided focused ultrasound surgerySettore MED/26 - NeurologiaFemaleRadiologymedicine.symptombrain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance-guided focused ultrasound surgery; mrgfus; mri; parkinson's disease; stereotactic techniqueMRIAdultmedicine.medical_specialtybrainEssential Tremormagnetic resonance–guided focused ultrasound surgery03 medical and health sciencesmedicineHumansmagnetic resonance-guided focused ultrasound surgeryUltrasonography InterventionalAgedThalamotomybusiness.industryMRgFUSmedicine.diseasestereotactic techniqueparkinson's diseaseParkinson’s diseaseSurgeryNeurology (clinical)businessSettore MED/36 - Diagnostica Per Immagini E Radioterapia030217 neurology & neurosurgeryFollow-Up StudiesNeurosurgical focus
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Focused Ultrasound in Neuroscience. State of the Art and Future Perspectives

2021

Transcranial MR-guided Focused ultrasound (tcMRgFUS) is a surgical procedure that adopts focused ultrasounds beam towards a specific therapeutic target through the intact skull. The convergence of focused ultrasound beams onto the target produces tissue effects through released energy. Regarding neurosurgical applications, tcMRgFUS has been successfully adopted as a non-invasive procedure for ablative purposes such as thalamotomy, pallidotomy, and subthalamotomy for movement disorders. Several studies confirmed the effectiveness of tcMRgFUS in the treatment of several neurological conditions, ranging from motor disorders to psychiatric disorders. Moreover, using low-frequencies tcMRgFUS sys…

OpinionComputer scienceNeurodegenerative diseaseFocused ultrasoundlcsh:RC321-57103 medical and health sciences0302 clinical medicineneurodegenerative diseaseslcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyBlood-brain barriertcMRgFUSLIFU0303 health sciencesEpilepsySettore MED/27 - NeurochirurgiaGeneral NeuroscienceSettore MED/37 - NeuroradiologiaPsychiatric disorderHIFUpsychiatric disordersfocused ultrasoundSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E RadioterapiaNeuroscienceneuro-oncology030217 neurology & neurosurgeryBrain Sciences
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Introducing 1,5 T MRgFUS

2015

MRgFUS is a new noninvasive thermal ablation method, consisting of a high focused ultrasound beam and a MR scanner for imaging and real-time thermal mapping. For decades, therapeutic transcranial ultrasound (tcMRgFUS) was assumed impossible. Novel technology using high-power phased array transducers and multiple channel driving electronics enabled a sharp focal point in the planned target through the intact skull allowing the use of this innovative technology for functional neurosurgery. Preliminary results have been published with systems operating with 3T MR units on patients with neurologic disorders such as essential tremor, tremor dominant idiopathic Parkinson's disease and neuropathic…

Settore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaMRgFUS tcMRgFUS neurological disorders 1.5T MRI
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Is there still a role for lesioning in functional neurosurgery: the Italian experience of delivering focused ultrasound high energy through a 1,5 tes…

2017

Settore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaSettore MED/36 - Diagnostica Per Immagini E Radioterapiafunctional neurosurgery trans-cranial Magnetic Resonance guided Focused Ultrasound Surgery (tcMRgFUS) Magnetic Resonance Imaging (MRI) High Intensities Focused Ultrasounds (HI-FU)
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THALAMIC PARCELLATION FOR TARGET IDENTIFICATION INTRANS-CRANIAL MR-GUIDED FOCUSED ULTRASOUND (TCMRGFUS)THALAMOTOMIES: A PRELIMINARY PROBABILISTC TRAC…

2019

Settore MED/27 - NeurochirurgiaTCMRGFUSSettore MED/37 - Neuroradiologia
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Is trans-cranial MR-guided Focused UltraSound a repeatable treatment option? Report of a successfully re-treated patient

2018

Background: In recent years, transcranial Magnetic Resonance-guided Focused UltraSounds (tcMRgFUS) treatments for functional neurological disorders are giving a new thrust to the field of therapeutic brain lesioning. This technique has been proven safe and effective in selected patients. Here we present the case of a patient affected by tremor combined with parkinsonism who underwent a second tcMRgFUS thalamotomy because of relapsing tremor after a few months from the first tcMRgFUS treatment. Materials and Methods: A 72-year-old, right-handed man, who came to our observation because of a disabling tremor affecting mainly his upper right limb and refusing any invasive surgical procedure. Hi…

Settore MED/27 - Neurochirurgiatranscranial Magnetic Resonance-guided Focused UltraSounds (tcMRgFUS) ParkinsonSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Thalamic parcellation for target identification in trans-cranial MR-guided Focused UltraSound (tcMRgFUS) thalamotomies: A preliminary probabilistic t…

2020

Thalamic parcellation tcMRgFUS probabilistic tractography
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Analysis of signal-to-noise ratio for a 2-channels coil developed to enable transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgF…

2018

mricMRgFUS
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TRANS-CRANIAL MRI-GUIDED FOCUSED ULTRASOUND SURGERY (TCMRGFUS): PRELIMINARY ITALIAN (AND WORLD-FIRST) EXPERIENCE AT 1,5 TESLA (first 3 cases treated)

2015

PURPOSE: We present our preliminary results achieved with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. Moreover, to our knowledge, this is the world-first tcMRgFUS system ever installed on a 1.5T MRI unit. TcMRgFUS is a promising new technology for the non-invasive treatment of neurologic disorders such as Essential Tremor (ET), tremor dominant idiopathic Parkinson's Disease (PD) and Neuropathic Pain (NP). This is a new method for focal targeting and lesioning of specific regions in the brain through intact skull by using high intensity focused ultrasound beam to achieve thermal ablation and …

tcMRgFUS functioanl neurosurgery 1.5T MRISettore MED/27 - NeurochirurgiaSettore MED/37 - Neuroradiologia
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