Search results for "cadherin"

showing 2 items of 112 documents

Stick around: Cell–Cell Adhesion Molecules during Neocortical Development

2021

The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need to establish and release adhesive interactions through cell surface receptors known as cell adhesion molecules (CAMs). Several types of CAMs have been described regulating different aspects of neurodevelopment. Whereas some of them mediate interactions with the extracellular matrix, others allow contact with additional cells. In this review, we will focus on the role of two important families of cell–cell adhesion molecules (C-CAMs), classi…

neocortical developmentOrganogenesisSynaptogenesisneuronsNeocortexReviewExtracellular matrixradial glia cellsaxon targetingCell surface receptorNectinmedicineAnimalsHumansCAMslcsh:QH301-705.5nectinsMammalsneuronal migrationsynaptogenesisNeocortexCell adhesion moleculeChemistryCadherinneurodevelopmental disordersclassical cadherinsGeneral MedicineCorticogenesismedicine.anatomical_structurelcsh:Biology (General)SynapsesCell Adhesion MoleculesNeuroscienceCells
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Comparative histological and immunohistochemical study of ameloblastomas and ameloblastic carcinomas

2017

Background This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). Material and Methods Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin (H&E) and immunohistochemical analysis with the following antibodies: cytokeratins 5,7,8,14 and 19, Ki-67, p53, p63 and the cellular adhesion molecules CD138 (Syndecan-1), E-cadherin and β-catenin. The mean score of the expression of Ki-67 and p53 labelling index (LIs) were compared between the groups using the t test. A value of p<0.05 was considered to be statistically significant. Results All cases were positive for CKs 5, 14 and 19, but negative fo…

tumorsMalePathologyAntibodies Neoplasmameloblastic carcinomaMalignant transformation0302 clinical medicineAmeloblastomaChildp63biologyki-67Middle Aged:CIENCIAS MÉDICAS [UNESCO]ImmunohistochemistryJaw Neoplasms030220 oncology & carcinogenesisKi-67immunohistochemistryUNESCO::CIENCIAS MÉDICASImmunohistochemistry//purl.org/pe-repo/ocde/ford#3.02.11 [https]Femalesyndecan-1 cd138Adultmedicine.medical_specialtyAdolescentgovernment.form_of_governmentcateninMalignancyAmeloblastoma03 medical and health sciencesYoung AdultDentistry Oral Surgery & MedicineexpressionmedicineHumansgeneGeneral DentistryOral Medicine and PathologyCadherinResearchcytokeratinsodontogenic030206 dentistrymedicine.disease//purl.org/pe-repo/ocde/ford#3.02.14 [https]Ameloblastic carcinomaOtorhinolaryngologyCateningovernmentbiology.proteinSurgeryodontogenic-tumorse-cadherin
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