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showing 10 items of 2320 documents

Guidance on allergenicity assessment of genetically modified plants

2017

Abstract This document provides supplementary guidance on specific topics for the allergenicity risk assessment of genetically modified plants. In particular, it supplements general recommendations outlined in previous EFSA GMO Panel guidelines and Implementing Regulation (EU) No 503/2013. The topics addressed are non‐IgE‐mediated adverse immune reactions to foods, in vitro protein digestibility tests and endogenous allergenicity. New scientific and regulatory developments regarding these three topics are described in this document. Considerations on the practical implementation of those developments in the risk assessment of genetically modified plants are discussed and recommended, where …

allergenicity assessmentVeterinary (miscellaneous)[SDV]Life Sciences [q-bio]newly expressed proteinsPlant ScienceGenetically modified cropsTP1-1185010501 environmental sciencesBiology01 natural sciencesMicrobiologyBiosafety0404 agricultural biotechnologyProtein digestibilityguidance; allergenicity assessment; newly expressed proteins; endogenous allergenicity; GMOTX341-6410105 earth and related environmental sciences2. Zero hungerbusiness.industryGMONutrition. Foods and food supplyChemical technology10079 Institute of Veterinary Pharmacology and Toxicology04 agricultural and veterinary sciencesFood safetyendogenous allergenicity040401 food science3. Good healthBiotechnologyScientific OpinionSettore AGR/11 - Entomologia Generale E Applicata570 Life sciences; biologynewly expressed proteinAnimal Science and ZoologyParasitologyImmune reactionbusinessRisk assessmentguidanceFood Science
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: The medical FASP genre as a teaching tool: authentic or doctored material?

2011

Abstract: This article falls within the scope of an action-based research project conducted at the Dijon School of Medicine. It focuses on the medical FASP genre as a potential pedagogical tool From December 2009 to April 2010, I asked 10 experienced health care professionals from various fields of medical practice, who had obtained an inter-university diploma in medical English, to fill in a questionnaire. The participants, who did not know the titles of the novels or the names of the novelists, were required to comment on six medically-based extracts taken from thrillers during continuing education classes. The aim of the questionnaire was to check the relevance of the specialized vocabul…

altération de l'authenticitéauthentic materialoutil pédagogique.pedagogical tool.doctored materialMedically-based fiction[SHS.GENRE]Humanities and Social Sciences/Gender studies[SHS.GENRE] Humanities and Social Sciences/Gender studiesFASP médicaletexte authentique[ SHS.GENRE ] Humanities and Social Sciences/Gender studies
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Molecular Insights on alpha-synuclein mediated membrane disruption: protein-lipid co-aggregates formation

2014

amyloid intrinsically disordered protein 2-photon fluorescence microscopy
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Regulatory sequences driving expression of the sea urchin Otp homeobox gene in oral ectoderm cells.

2005

Abstract PlOtp (Orthopedia), a homeodomain-containing transcription factor, has been recently characterized as a key regulator of the morphogenesis of the skeletal system in the embryo of the sea urchin Paracentrotus lividus . Otp acts as a positive regulator in a subset of oral ectodermal cells which transmit short-range signals to the underlying primary mesenchyme cells where skeletal synthesis is initiated. To shed some light on the molecular mechanisms involved in such a process, we begun a functional analysis of the cis -regulatory sequences of the Otp gene. Congruent with the spatial expression profile of the endogenous Otp gene, we found that while a DNA region from −494 to +358 is s…

animal structuresMesenchymeTransgeneGreen Fluorescent ProteinsEctodermSettore BIO/11 - Biologia MolecolareBiologyGreen fluorescent proteinAnimals Genetically ModifiedEctodermGeneticsmedicineAnimalsRNA MessengerMolecular BiologyGeneTranscription factorSea urchin development Skeletogenesis Orthopedia homeobox gene Oral ectoderm microinjectionHomeodomain ProteinsBase SequenceGenes HomeoboxGene Expression Regulation DevelopmentalDNAMolecular biologyRecombinant Proteinsmedicine.anatomical_structureRegulatory sequenceembryonic structuresParacentrotusHomeoboxDigestive SystemDevelopmental BiologyTranscription FactorsGene expression patterns : GEP
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Cellular Composition and Organization of the Subventricular Zone and Rostral Migratory Stream in the Adult and Neonatal Common Marmoset Brain

2011

The adult subventricular zone (SVZ) of the lateral ventricle contains neural stem cells. In rodents, these cells generate neuroblasts that migrate as chains toward the olfactory bulb along the rostral migratory stream (RMS). The neural-stem-cell niche at the ventricular wall is conserved in various animal species, including primates. However, it is unclear how the SVZ and RMS organization in nonhuman primates relates to that of rodents and humans. Here we studied the SVZ and RMS of the adult and neonatal common marmoset (Callithrix jacchus), a New World primate used widely in neuroscience, by electron microscopy, and immunohistochemical detection of cell-type-specific markers. The marmoset …

animal structuresRostral migratory streamNeurogenesisanimal diseasesSubventricular zoneArticlecommon marmosetNeural Stem CellsNeuroblastrostral migratory streamCell MovementLateral Ventriclesbiology.animalmedicineAnimalsHumansStem Cell NicheCell ProliferationbiologyGeneral NeuroscienceNeurogenesisBrainMarmosetsubventricular zoneCallithrixbiology.organism_classificationImmunohistochemistryMagnetic Resonance ImagingCallithrixNeural stem cellOlfactory bulbMicroscopy Electronmedicine.anatomical_structureAnimals Newbornnervous systemNeuroscience
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Production of cecropin A in transgenic rice plants has an impact on host gene expression.

2008

Summary Expression of the cecropin A gene in rice confers resistance to the rice blast fungus Magnaporthe oryzae. In this study, a polymerase chain reaction-based suppression subtractive hybridization approach was used to generate a cDNA macroarray from the elite japonica rice (Oryza sativa L.) cultivar ‘Senia’. Gene expression studies revealed that the expression of components of the protein secretory and vesicular transport machinery is co-ordinately activated at the pre-invasive stage of infection of rice by the blast fungus. Comparisons of gene expression between wild-type and cecropin A plants revealed the over-expression of genes involved in protection against oxidative stress in tran…

animal structuresTransgenePlant ScienceGenetically modified cropsBiologyEndoplasmic ReticulumGene Expression Regulation PlantComplementary DNAGene expressionGeneOligonucleotide Array Sequence AnalysisPlant DiseasesGeneticsExpressed Sequence TagsOryza sativafungifood and beveragesOryzaHydrogen PeroxidePlants Genetically ModifiedGenetically modified riceCell biologyMagnaportheProtein TransportCecropinHost-Pathogen InteractionsAgronomy and Crop ScienceBiotechnologyAntimicrobial Cationic PeptidesPlant biotechnology journal
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Somatic embryogenesis from hypocotyl callus cultures of Digitalis obscura L.

1986

Hypocotyl-derived calli obtained in agar solidified medium with several growth regulator combinations gave rise to proembryonal masses and globular embryos when transferred to liquid media with lower growth regulator and higher NH4HO3 levels. By transferring cultures from liquid media to different solidified media, new embryo formation took place, but further development of these embryos or those previously induced depended on the characteristics of these media. Normal development was only achieved on 8 g/l agar solidified medium without growth regulators. Typical cotyledonary embryos developed into whole plants when transferred to this same medium.

animal structuresfood.ingredientbiologySomatic embryogenesisScrophulariaceaeDigitalis obscuraEmbryoPlant ScienceGeneral Medicinebiology.organism_classificationHypocotylTissue culturefoodCallusembryonic structuresBotanyAgarAgronomy and Crop SciencePlant cell reports
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Esteve Graset. Una dramaturgia interdisciplinaria. Materiales del discurso escénico en Esteve Graset

2016

Esteve Graset es uno de los artistas españoles más desconocidos y a la vez interesantes de la escena nacional e internacional de las últimas décadas. Es autor de textos, instalaciones escénicas, importantes trabajos sobre la voz humana (conciertos) y muchas producciones escénicas con actores y bailarines en las que se pone en práctica la suma de todos sus conocimientos e inquietudes. Con los materiales de sus propias representaciones organiza instalaciones en las que da vida a los objetos. Su personalidad independiente y evolutiva, su discurso como actor, director, autor, creador y pedagogo, así como la gran variedad de disciplinas artísticas que contempla su obra, y su compromiso con el ti…

arena teatrocantos de Lorcala barraca de feriainstalación tubosfenómenos atmosféricosvoz exposiciónmaniobras urbanasextrarradiosorganuminstalaciontetralogía de la miseriaventana traseral´arc de teatredónde está la nocheesteve grasetvariaciones sobre macbethexpropiadosbrau teatrearnau1+1 (1989)mirar de no darle al gatopalos de lluviaon són els somnisfantasmaseme trescomte arnaul´actor que dansasistema solarUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASinstalación paisaje con guadañasfase I: usos domésticosopeningteatro posdramaticomagrinyanacentre de practiques teatralsusos domésticos [fase I]concierto fluidosinstalación water clock/instrumentdramaturgia interdisciplinariatrilogía del mar:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]tetralogia de la vozvoz voces tambiénel espacio/instalacióncallejero
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De la performance musicale dans la Guyane traditionnelle : expression cognitive singulière d?une musique-verbe

2021

Guianese culture and traditional music, here evoked, are various. It is more a transcultural process that, along centuries, gave an original result born in the Americas, in Guiana in this case. It is a form of refoundation, of recreation of cultures and new human beings generally called Creoles. The musical performance, that I study here, is the echo of social and cultural space of this reformulation of thought, life, and conception of the world. It is, as well, a mean of transposition and transformation of the values issued of diverse sources and categories. It is in no way a second-rate cultural practice, as it is the place where were born philosophies and actions for common life as well …

as it is the place where were born philosophies and actions for common life as well as for individual life. This organization of the musical experience requires several levels of readings to better understand the underlying performance that is the issue discussed here. What is then the subject of the musical performance in French Guianese traditional society? What are the implementation techniques and the intrinsic forms of knowledge? What is the creation process and for what goal? Without a doubtlifeUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASand conception of the world. It isrevista de investigación musical: territorios para el arte 590908 2021 7 8182062 De la performance musicale dans la Guyane traditionnelle : expression cognitive singulière d?une musique-verbe Anakesa Kululukaalong centuriesin Guiana in this case. It is a form of refoundationis the echo of social and cultural space of this reformulation of thoughtquestions arising from this issue are still numerous and varied. And the answers one can give are just as numerous. The few basic questions mentioned above are a theme for the reflection conducted here by the author on traditional music of French Guiana. 105 1442386-8260 13268 Itamara mean of transposition and transformation of the values issued of diverse sources and categories. It is in no way a second-rate cultural practicehere evokedof recreation of cultures and new human beings generally called Creoles. The musical performancegave an original result born in the Americasterritorios para el arte 590908 2021 7 8182062 De la performance musicale dans la Guyane traditionnelle : expression cognitive singulière d?une musique-verbe Anakesa Kululuka [revista de investigación musical]Apollinaire Guianese culture and traditional musicas well:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]that I study hereare various. It is more a transcultural process that
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Gli interessi moratori usurari ma contra legem

2021

Il saggio muove dalla recente sentenza delle Sezioni unite della Corte di cassazione sull'inclusione degli interessi moratori nell'ambito di applicazione della fattispecie dell'usura in astratto. La risposta data dalle Sezioni unite è positiva ed essa va pienamente condivisa, perché gli interessi moratori rientrano tra i costi dei finanziamenti, ancorché eventuali. Gli argomenti a sostegno di questa conclusione sono però totalmente errate e essi destano allarme perché si presentano chiaramente contra legem. The essay starts from the recent judgment of the Sezioni unite of the Court of Cassation on the inclusion of interests for non performance within the scope of the figure of usury so call…

average global effective rate (so called TEGM) nullity art. 1224 c.c.usury interests for non perfomance principle of symmetrySettore IUS/01 - Diritto Privato
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