Search results for "carbohydrate"

showing 10 items of 882 documents

Cyanide inhibits respiration yet stimulates aerobic growth of Zymomonas mobilis

2000

Potassium cyanide at submillimolar concentrations (20-500 microM) inhibited the high respiration rates of aerobic cultures of Zymomonas mobilis but, remarkably, stimulated culture growth. In batch culture, after an extended lag phase, exponential growth persisted longer, resulting in higher biomass densities. In aerobic chemostat cultures, elevated biomass concentration was observed in the presence of cyanide. This growth stimulation effect is attributed to decreased production of the inhibitory metabolite acetaldehyde at lowered respiration rates, when more reducing equivalents are channelled to alcohol dehydrogenase. Growth in the presence of cyanide did not alter the membrane cytochrome …

ZymomonasMembranesbiologyCellular respirationCyanideRespiratory chainPotassium cyanideAcetaldehydeAcetaldehydeCarbohydrate metabolismbiology.organism_classificationMicrobiologyZymomonas mobilisAerobiosischemistry.chemical_compoundAdenosine TriphosphateGlucoseOxygen ConsumptionchemistryBiochemistryRespirationCytochromesBiomassPotassium CyanideCell DivisionMicrobiology
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The shell matrix and microstructure of the Ram's Horn squid: Molecular and structural characterization.

2020

20 pages; International audience; Molluscs are one of the most diversified phyla among metazoans. Most of them produce an external calcified shell, resulting from the secretory activity of a specialized epithelium of the calcifying mantle. This biomineralization process is controlled by a set of extracellular macromolecules, the organic matrix. In spite of several studies, these components are mainly known for bivalves and gastropods. In the present study, we investigated the physical and biochemical properties of the internal planispiral shell of the Ram's Horn squid Spirula spirula. Scanning Electron Microscope investigations of the shell reveal a complex microstructural organization. The…

[SDE] Environmental SciencesBiomineralizationProteomicsRam's horn squidCarbohydratesChitinProteomicsCalcium Carbonate03 medical and health scienceschemistry.chemical_compoundCalcification PhysiologicChitinStructural BiologyAnimal ShellsExtracellularShellAnimals14. Life underwaterMantle (mollusc)[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMicrostructure030304 developmental biologySerine protease0303 health sciencesbiology030302 biochemistry & molecular biologyDecapodiformesProteomicbiology.organism_classificationSpirula spirulaCephalopod[SDV.IB.BIO] Life Sciences [q-bio]/Bioengineering/Biomaterials[SDE.BE] Environmental Sciences/Biodiversity and Ecologychemistry[SDE]Environmental SciencesBiophysicsbiology.protein[SDE.BE]Environmental Sciences/Biodiversity and EcologyBiomineralizationJournal of structural biology
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Mollusc shellomes: Past, present and future.

2020

13 pages; International audience; In molluscs, the shell fabrication requires a large array of secreted macromolecules including proteins and polysaccharides. Some of them are occluded in the shell during mineralization process and constitute the shell repertoire. The protein moieties, also called shell proteomes or, more simply, 'shellomes', are nowadays analyzed via high-throughput approaches. These latter, applied so far on about thirty genera, have evidenced the huge diversity of shellomes from model to model. They also pinpoint the recurrent presence of functional domains of diverse natures. Shell proteins are not only involved in guiding the mineral deposition, but also in enzymatic a…

[SDE] Environmental SciencesProteomeLarge arrayCarbohydratesMacroevolutionEmergent propertyLow complexity03 medical and health sciencesStructural BiologyAnimal Shells[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]ShellAnimalsBiomineralComplex systems biology[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsShellomicsComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesMineralsMatrixChemistry030302 biochemistry & molecular biologyMineral depositionEvolvability[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyEvolutionary biologyMolluscaProteome[SDE]Environmental Sciences[SDV.BA.ZI] Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyMolluscJournal of structural biology
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Task-specific ionic liquid for the depolymerisation of starch-based industrial waste into high reducing sugars

2014

Development of a simple route for the catalytic conversion of starch-based industrial waste (potato peels) and potato starch into reducing sugars was investigated in two ionic liquids for comparison – 1-allyl-3-methylimidazolium chloride [AMIM]Cl and 1-(4-sulfobutyl)-3-methylimidazolium chloride [SBMIM]Cl. Over a two hour period, a 20 wt% solution containing up to 43% and 98% of reducing sugars at low temperature in aqueous [SBMIM]Cl was achieved for the starch-based waste and the potato starch, respectively. In addition, the use of microwave and low frequency ultrasound to perform the depolymerisation of the raw starch-based material was explored and compared with conventional heating proc…

[SDE] Environmental ScienceshydrolyysiStarchtask-specific ionic liquidsultrasoundsChlorideCatalysisIndustrial wasteCatalysismikroaallotchemistry.chemical_compoundHydrolysis[CHIM] Chemical Sciencesmedicine[CHIM]Chemical SciencesOrganic chemistryta116Potato starchComputingMilieux_MISCELLANEOUScarbohydrates reducing sugarsAqueous solutionGeneral Chemistry6. Clean waterchemistry[SDE]Environmental SciencesIonic liquidNuclear chemistrymedicine.drugCatalysis Today
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Interactions between aroma compounds and food matrix

2017

Interactions between aroma compounds and food matrix

[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionpolyphenolcarbohydratephysico-chemical characteristic[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritiondigestive oral and skin physiologynon-volatile compoundfood and beveragescomplex matrice[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Characterization of the biosynthesis of saponins during seed development in peas (Pisum sativum)

2019

National audience; The use of pulses as ingredients for the production of food products rich in plant proteins is increasing. However, protein fractions prepared from pea or other pulses contain significant amounts of saponins, glycosylated triterpenes which can impart a bitter taste to the final food product. Bitter flavours are currently either removed by energy-requiring physico-chemical treatments or masked by additives. We are in the process of identifying and characterizing the genes involved in saponin biosynthesis during pea seed development, with the objective of identifying mutants in which seed saponins no longer accumulate. To do this we have applied a saponin extraction protoco…

[SDV] Life Sciences [q-bio][SDE] Environmental Sciencescarbohydrates (lipids)[SDV]Life Sciences [q-bio]parasitic diseases[SDE]Environmental Sciencesfood and beverages[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal Biologyoff-flavourproteincomplex mixturessaponin
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Muscle Function Differences between Patients with Bulbar and Spinal Onset Amyotrophic Lateral Sclerosis. Does It Depend on Peripheral Glucose?

2021

Background: One of the pathogenic mechanisms of ALS disease is perturbed energy metabolism particularly glucose metabolism. Given the substantial difference in the severity and the prognosis of the disease, depending on whether it has a bulbar or spinal onset, the aim of the study was to determine metabolic differences between both types of ALS, as well as the possible relationship with muscle function. Materials and Methods: A descriptive, analytical, quantitative, and transversal study was carried out in hospitals and Primary Care centers in the region of Valencia, Spain. Fasting glucose and alkaline phosphatase (AP) levels in venous blood, muscle percentage, fat percentage, muscle streng…

amyotrophic lateral sclerosis:Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose [Medical Subject Headings]lcsh:Medicine:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior::Fasting [Medical Subject Headings]DiseaseGastroenterology:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineAmyotrophic lateral sclerosisglucosespinal onset ALS:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Phosphoric Monoester Hydrolases::Alkaline Phosphatase [Medical Subject Headings]:Health Care::Health Care Facilities Manpower and Services::Health Facilities::Hospitals [Medical Subject Headings]0303 health sciences:Anatomy::Musculoskeletal System::Muscles [Medical Subject Headings]General MedicineVenous bloodFuerza muscular:Health Care::Health Services Administration::Patient Care Management::Comprehensive Health Care::Primary Health Care [Medical Subject Headings]PeripheralAlkaline phosphataseFosfatasa alcalinaalkaline phosphatasemedicine.medical_specialtyBarthel indexbulbar onset ALS:Diseases::Nervous System Diseases::Neurodegenerative Diseases::Motor Neuron Disease::Amyotrophic Lateral Sclerosis [Medical Subject Headings]Carbohydrate metabolismResistencia a la insulinaArticle03 medical and health sciences:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance [Medical Subject Headings]Insulin resistance:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Muscle Strength [Medical Subject Headings]Internal medicinemedicine030304 developmental biology:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]Muscle strengthbusiness.industrylcsh:RInsulin resistance:Phenomena and Processes::Metabolic Phenomena::Metabolism::Energy Metabolism [Medical Subject Headings]medicine.diseaseAtrofia muscular espinalGlucosa:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings]businessEsclerosis amiotrófica lateral030217 neurology & neurosurgery
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Photodegradation of lincomycin in aqueous solution

2006

Aqueous solutions of lincomycin were irradiated with UV light in homogeneous and heterogeneous systems. Lincomycin disappeared in both systems but the presence ofTiO2noticeably accelerated the degradation of the antibiotic in comparison with direct photolysis. The rate of decomposition was dependent on the concentration of lincomycin and followed a pseudo-first-order kinetics. Photolysis involved only the oxidation of lincomycin without mineralization. Differently, the treatment withTiO2and UV light resulted in a complete mineralization of the antibiotic. The degradation pathways involved S- and N-demethylation and propyldealkylation. The mineralization of the molecule led to the formation …

animal diseaseslcsh:TJ807-830Kineticslcsh:Renewable energy sourcesPhotochemistrychemistry.chemical_compoundmedicineGeneral Materials ScienceAmmoniumSulfatePhotodegradationSettore ING-IND/24 - Principi Di Ingegneria ChimicaAqueous solutionRenewable Energy Sustainability and the EnvironmentChemistrylyncomicin photodegradation TiO2General ChemistryMineralization (soil science)biochemical phenomena metabolism and nutritionbacterial infections and mycosesDecompositionAtomic and Molecular Physics and OpticsLincomycincarbohydrates (lipids)Settore CHIM/07 - Fondamenti Chimici Delle Tecnologiemedicine.drug
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Fructose 2,6-bisphosphate as a signal for changing from sugar to lipid oxidation during flight in locusts

1986

AbstractFlight in locusts is initially powered mainly by carbohydrate but if flight is to be sustained, as in migration, the animals have to utilize fat as the predominant fuel. The molecular basis of this metabolic switch has not been identified. Fructose 2,6-bisphosphate is a potent activator of 6-phosphofructokinase (EC 2.7.1.11) purified from locust flight muscle. After the first few minutes of flight in the locust the concentration of fructose 2,6-bisphosphate in the flight muscle falls dramatically, which should lead to a decrease in the activity of 6-phosphofructokinase as part of the mechanism to conserve carbohydrate during prolonged flight.

animal structures6-phosphofructokinaseBiophysicsBiochemistrychemistry.chemical_compoundLipid oxidationStructural BiologyGeneticsGlycolysis(Locust flight muscle)SugarMolecular BiologyFructose 2biologyActivator (genetics)FructoseCell BiologyFat oxidationCarbohydratebiology.organism_classificationchemistryBiochemistryFructose 26-bisphosphate6-bisphosphateGlycolysisInsect migrationLocustFEBS Letters
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Activation of TRK Genes in Ewingʼs Sarcoma Trk A Receptor Expression Linked to Neural Differentiation

1997

Trk receptors have been identified by immunohistochemical methods in primitive neuroectodermal tumor (PNET)/Ewing's sarcoma (ES). However, the presence of different members of the Trk family of receptors in PNET/ES has not been specified. We have examined whether Trk A, B, and C receptors are specifically expressed in ES both with and without features of neural differentiation. Ten ES tumors (five primary tumors of bone and five extraosseous tumors transplanted into nude mice) were investigated for expression of Trk receptors by immunohistochemistry and reverse transcription-polymerase chain reaction. One primary ES and the five grafted ES tumors exhibited signs of neural differentiation; t…

animal structuresReceptor expressionReceptors Nerve Growth FactorSarcoma EwingBiologyPathology and Forensic MedicineMiceProto-Oncogene ProteinsmedicineAnimalsNeuroectodermal Tumors PrimitiveReceptor trkCReceptor trkAReceptorReceptor Ciliary Neurotrophic FactorMolecular BiologyNeuronsMembrane ProteinsReceptor Protein-Tyrosine KinasesEwing's sarcomaCell DifferentiationCell BiologyProtein-Tyrosine Kinasesmedicine.diseaseMolecular biologyGene Expression Regulation Neoplasticenzymes and coenzymes (carbohydrates)nervous systemTrk receptorPrimitive neuroectodermal tumorembryonic structuresImmunohistochemistrySarcomaImmunostainingDiagnostic Molecular Pathology
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