Search results for "carrier"
showing 10 items of 1256 documents
Sustained release of silibinin to the posterior segment of the eye by mucoadhesive NLC
2015
AMPA Receptor Auxiliary Proteins of the CKAMP Family
2019
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular localization and function of AMPA receptors. The four CKAMP family members CKAMP39/shisa8, CKAMP44/shisa9, CKAMP52/shisa6 and CKAMP59/shisa7 differ in their expression profile and their modulatory influence on AMPA receptor function. In this review, I report about recent findings on the differential roles of CKAMP family members.
Covalently Modified Halloysite Clay Nanotubes: Smart Nanomaterials for Drug Delivery Applications
2017
Halloysite nanoclays (HNTs) are promising nanomaterials because of their versatile properties, such as hollow tubular morphology and tunable surface chemistry. HNTs are biocompatible, no toxic and abundantly available at low cost. Due to these characteristics HNTs are suitable for development of hybrid sustainable materials, which are perspective for polymeric matrices reinforcement, active food packaging and drug delivery. HNTs are quite polydisperse in size with a length of ca. 1 m, while the external diameter and the lumen range between 50-80 nm and 10-15 nm, respectively. Chemically, halloysite is composed of gibbsite octahedral sheet (Al-OH) groups on the inner surface and siloxane (S…
Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications
2017
Halloysite (HNT) is a promising natural nanosized tubular clay mineral that has many important uses in different industrial fields. It is naturally occurring, biocompatible, and available in thousands of tons at low cost. As a consequence of a hollow cavity, HNT is mainly used as nanocontainer for the controlled release of several chemicals. Chemical modification of both surfaces (inner lumen and outer surface) is a strategy to tune the nanotube's properties. Specifically, chemical modification of HNT surfaces generates a nanoarchitecture with targeted affinity through outer surface functionalization and drug transport ability from functionalization of the nanotube lumen. The primary focus …
Use of nanostructures as oxygen carriers in chemical looping combustion
2013
The usage of fossils fuels has increased carbon dioxide emissions, and the carbon dioxide is responsible for global warming and sea level rising. One of the most promising ways of carbon capturing from the power plants is chemical looping combustion (CLC). CLC is based on the alternating oxidation and reduction reactions on the air and fuel reactors. Oxygen and energy needed for combustion between the reactors is transferred by an oxygen carrier. Oxygen carrier is usually made of metal or metal oxide. One big hindrance towards commercial use of CLC is slow reaction kinetics of oxygen carriers. One possible solution for the problem is to replace the conventional carriers by nanoscale oxygen …
Ecofriendly Biopolymer-Based Nanocomposite Films with Improved Photo-Oxidative Resistance
2022
The interest towards high performance biopolymer-based materials increases continuously and, to guarantee appropriately industrial applications, the photo-oxidative resistance and stability of these materials must be adequately addressed. In this study, innovative biopolymer-based nanocomposites, i.e., Polyamide 11 (PA11), containing ad-hoc modified Layered Double Hydroxides (LDH), were successfully formulated and characterized. Particularly, LDH were considered carriers for hindered amine light stabilizing molecules, so two different hindered amine moieties (HALS1 and HALS2) were anchored on LDH layered internal structures and/or outer surfaces. The presence of HALS1 and HALS2 in LDH were …
A Matrix Model For An Energy Management System Based On Multi-Carrier Energy Hub Approach
2015
The INGRID FP7 European co-funded project studies several methodologies concerning hydrogen production and storage, aiming to provide services to electricity system operators for suitably balancing electrical supply and demand. In such a context, the problem of integrating different carriers into a single multi-hub optimiser represents a challenging topic for the research. This paper depicts the Energy Management System (EMS) of the plant which will be developed and built as a prototype of the INGRID system. The approach followed for the EMS design and development takes the cue from the matrix model presented in the rest of the paper, as well as the general optimisation problem formulation …
Synthesis and preliminary in vivo evaluation of well-dispersed biomimetic nanocrystalline apatites labeled with positron emission tomographic imaging…
2015
In recent years, biomimetic synthetic apatite nanoparticles (AP-NPs), having chemical similarity with the mineral phase of bone, have attracted a great interest in nanomedicine as potential drug carriers. To evaluate the therapeutic perspectives of AP-NPs through the mechanisms of action and organs they interact with, the noninvasive monitoring of their in vivo behavior is of paramount importance. To this aim, here the feasibility to radiolabel AP-NPs ("naked" and surface-modified with citrate to reduce their aggregation) with two positron emission tomographic (PET) imaging agents ([F-18]NaF and Ga-68-NO(2)AP(BP)) was investigated. [F-18]NaF was used for the direct incorporation of the radi…
Covalently modified nanoclays: synthesis, properties and applications
2020
Abstract Clay minerals are phyllosilicates of nanoscale dimensions. According to their ability to entrap and release organic moieties, they have found applications in several fields, such as drug carrier and delivery, support for catalyst, environmental remediation and filler for polymeric matrices. The possibility to modify, by covalent linkage, their surfaces gives the possibility to form new nanomaterials with improved properties respect to the pristine clay minerals. In this chapter, the modifications of the siloxane surfaces of the most representative clay minerals, namely montmorillonite, sepiolites, laponite and halloysite were reviewed and discussed.
The effect of oxygenation on the radiation hardness of silicon studied by surface photovoltage method
2002
The effect of oxygenation on the radiation hardness of silicon detectors was studied. Oxygen-enriched and standard float-zone silicon pin-diodes and oxidized samples were processed and irradiated with 15-MeV protons. After the irradiations, the surface photovoltage (SPV) method was applied to extract minority carrier diffusion lengths of the silicon samples. Adding oxygen to silicon was found to improve the radiation hardness of silicon. The effect was visible in minority carrier diffusion lengths as well as in reverse bias leakage currents. The suitability of SPV method for characterizing irradiated silicon samples was proved.