Search results for "catastro"
showing 10 items of 122 documents
Une catastrophe qui rampe : Dijon face aux insectes (c. 1450- c. 1550)
2005
International audience
Contribution of musculoskeletal pain to postural balance in community-dwelling people aged 75 years and older.
2010
Background. Balance is among the most important prerequisites for safe and independent mobility. Whether musculoskeletal pain is related to standing balance impairment has received limited attention. The aim of this study was to examine the association of musculoskeletal pain with the control of balance in older people. Methods. A total of 605 participants aged 75 years and older (mean age 80.4, 71 % women) were interviewed about presence and severity of musculoskeletal pain. Balance was measured by a force platform, and impaired balance was defined as a high sway velocity moment or inability to maintain semitandem standing. Results. Musculoskeletal pain was reported by 48% of the participa…
L'évolution de la représentation des catastrophes en Méditerranée à travers la peinture : le passage du fatalisme au rationalisme
2007
International audience
Making a mountain out of a molehill: on the role of the rostral dorsal anterior cingulate and dorsomedial prefrontal cortex in conscious threat appra…
2013
According to appraisal theories fear and anxiety are elicited by the subjective evaluation of a situation or internal state as threatening. From this perspective anxiety disorders result from maladaptive, exaggerated threat appraisals that over-estimate the threatening consequences of often innocuous stimuli and situations. When these threat over-estimations occur at the level of conscious processing, they are referred to as catastrophizing and worrying. Both are major pathogenic processes in many clinical theories of anxiety. Until recently, little has been known about the neurobiological basis of normal and pathological conscious threat appraisal. Here, we review functional neuroimaging s…
P11. Impact of emotional stress on pain perception in an experimental pain model
2007
MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
2019
Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo box domain (PBD), which has a key regulatory function for kinase activity and substrate recognition. We report on 3-bromomethyl-benzofuran-2-carboxylic acid ethyl ester (designated: MCC1019) as selective PLK1 inhibitor targeting PLK1 PBD. Cytotoxicity and fluorescence polarization-based screening were applied to a library of 1162 drug-like compounds to identify potential inhibitors of PLK1 PBD. The activity of compound MC1019 against the PLK1…
On universality of critical behavior in the focusing nonlinear Schrödinger equation, elliptic umbilic catastrophe and the Tritronquée solution to the…
2008
We argue that the critical behavior near the point of “gradient catastrophe” of the solution to the Cauchy problem for the focusing nonlinear Schrodinger equation \(i\epsilon \varPsi _{t}+\frac{\epsilon^{2}}{2}\varPsi _{xx}+|\varPsi |^{2}\varPsi =0\) , e ≪1, with analytic initial data of the form \(\varPsi (x,0;\epsilon)=A(x)e^{\frac{i}{\epsilon}S(x)}\) is approximately described by a particular solution to the Painleve-I equation.
Transformation des milieux naturels et conscience environnementale à la fin du Moyen Âge : une esthétique du paysage manquante ?
2010
À partir du XIVe siècle, des exemples de plus en plus nombreux montrent que la société médiévale percevait les transformations environnementales opérées par l’action anthropique. Une réflexion, tendant à octroyer à l’aménagement humain du milieu naturel une part des responsabilités en cas de catastrophes, apparaît ainsi régulièrement dans un discours qui opposait la plupart du temps l’aspect négatif et dangereux de cette transformation du paysage à la nostalgie d’une nature « ancienne », marquée par la stabilité. Un souci environnemental important de préservation du milieu naturel, faisant plonger très loin les racines du discours écologique contemporain, se manifeste ainsi très tôt. Faisan…
Algunas reflexiones sobre la percepción del cambio climático en una muestra de población adulta de nivel cultural medio
1994
El cambio climático es uno de los aspectos del Medio Ambiente que mayor eco social ha alcanzado en los últimos años. El tema ha trascendido de los centros de investigación a la opinión pública de manera distorsionada, debido, en gran parte, a medios de comunicación poco rigurosos. Este trabajo reflexiona sobre la percepción del fenómeno por parte de una muestra de población adulta de nivel cultural medio, que da por sentado un cambio climático importante, producido en los últimos años por el hombre y que ha originado la mayor parte de catástrofes naturales de tipo hidrometeorológico. Esta imagen catastrofista contrasta con la indeterminación que muestra la comunidad científica, que pone de …
Bader's analysis of the electron density in the Pbca enstatite - Pbcn protoenstatite phase transition
2011
The Bader’s topological analysis of the electron density obtained via ab initio quantum mechanical simulation at Hartree–Fock and DFT level has been performed for experimentally in situ heated structures of enstatite–protoenstatite MgSiO 3 . The measurements have been performed in the temperature range 1200–1400 K. The work was aimed at characterizing both the evolution of the electron arrangement in the crystal and that of the crystal-structure at the enstatite–protoenstatite phase transition in terms of topology of the electron density, with particular care about the Mg–O and the O–O bonds. The observed breaking of some chemical bonds with increasing temperature and/or due to the phase tr…