Search results for "ceny"
showing 10 items of 117 documents
Pre-imaginal conditioning alters adult sex pheromone response in
2018
Pheromones are chemical signals that induce innate responses in individuals of the same species that may vary with physiological and developmental state. In Drosophila melanogaster, the most intensively studied pheromone is 11-cis-vaccenyl acetate (cVA), which is synthezised in the male ejaculatory bulb and is transferred to the female during copulation. Among other effects, cVA inhibits male courtship of mated females. We found that male courtship inhibition depends on the amount of cVA and this effect is reduced in male flies derived from eggs covered with low to zero levels of cVA. This effect is not observed if the eggs are washed, or if the eggs are laid several days after copulation. …
Propriétés et performances de phosphines ferrocéniques dans le couplage C-O, C-S et C-N : nouvelles méthodologies de synthèse au palladium
2012
Multidentate ligands usually show great activities in low loading organometallic catalysis in palladium. Among these ligands, the use of ferrocenyl polyphosphane ligands give interesting results. Robust palladium-ferrocenyl triphosphane catalytic systems have permitted to obtain biarylamines and aryl-heteroaryl ethers in the presence of low catalytic loadings. DFT studies on catalytic cycle during formation of aryl-heteroaryl ethers were carried out. The presence of third phosphino group stabilizes a transition state which enhances the rate of the reductive elimination. Triarylamines were obtained with ferrocenyl diphosphane in the presence of 2 mol% of palladium loading. Moderate to excell…
Inter- and Intramolecular Anodic Nucleophilic Substitutions of Porphyrins. Reactivity of the resulting products
2020
This manuscript presents the functionalization of porphyrins by anodic nucleophilic substitution (SNAn). After an introduction describing generalities on porphyrin, the 2nd chapter deals with the 2-step synthesis of primary aminoporphyrins. The 1st electrochemical step consists in oxidizing the porphyrin at the 1st oxidation potential in the presence of pyridine. The formed pyridinium-porphyrin is then transformed into an amine by opening the pyridinium fragment by nucleophilic attack of piperidine.The 3rd chapter presents the synthesis and redox reactivity of porphyrins substituted with one (or several) aromatic groups carrying an imine function (thiopyrimidine, quinoline and aminopyridine…
CCDC 249547: Experimental Crystal Structure Determination
2005
Related Article: M.Viciano, E.Mas-Marza, M.Poyatos, M.Sanau, R.H.Crabtree, E.Peris|2005|Angew.Chem.,Int.Ed.|44|444|doi:10.1002/anie.200461918
Phosphine Ligands Based on the Ferrocenyl Platform: Advances in Catalytic Cross-Couplings
2023
Ferrocenyl skeletons tagged with a variety of donor atoms (metalloligands) have become popular in modern metal-catalyzed organic transformations, broadening the applications. Ferrocenylphosphines, such as 1′-bis(diphenylphosphino)ferrocene (dppf), have been widely used as metalloligands in academic and industrial research, motivating further investigation into novel ferrocenylphosphine ligands. The current review concentrated non-exhaustively on emblematic applications of different ferrocenylphosphine ligands in transition metal-catalyzed cross-coupling strategies. Initially, the stereochemical aspects of the ferrocenyl skeleton, nomenclature, and applications of chiral ferrocenyl phosphine…
General route to dissymmetric heteroannular-functionalized ferrocenyl 1,2-diphosphines: selective synthesis and characterization of a new class of tr…
2006
Several monosubstituted-cyclopentadienyl anions (A-Li) and [1,2-bis(diphenylphosphino)-4-tert-butylcyclopentadienyl]lithium (B-Li) react with FeCl2 to afford a novel class of multidentate ferroceny...
Diastereoselective Synthesis of Dialkylated Bis(phosphino)ferrocenes: Their Use in Promoting Silver-Mediated Nucleophilic Fluorination of Chloroquino…
2017
International audience; The diastereoselective synthesis of dialkylated ferrocenyl bis(phosphane)s bearing aryl, alkyl, and hetero- or polycyclic substituents on the phosphino groups is reported, together with their characterization in the solid state by X-ray structure analysis and in solution by multinuclear NMR spectroscopy. Introduction of various alkyl groups on the ferrocene backbone, namely, tert-butyl, isopropyl, and trimethylsilyl, has a significant influence on the stereoselectivity of the ensuing lithiation/phosphination reactions. Only the introduction of the tert-butyl groups ensures both a high yield and perfect diastereoselectivity, which leads to the exclusive formation of t…
effects of early combined pheromone and food exposure on the behavioral development of adult drosophila melanogaster
2023
In Drosophila melanogaster, pheromonal communication is mainly mediated through sex-specific cuticular hydrocarbons (and derived compounds) and the male lipidic pheromone 11 - cis - Vaccényl Acétate (cVA). When deposited together on the feeding substrate they attract conspecifics males and females, promoting mating and collective behaviors. Initially described as stereotyped, recent findings showed that adult response to pheromones could be plastic and depend on the juvenile experience of an individual (i.e. imprinting). In this context, we studied cVA imprinting through its aggregative effect in individuals whose imprinting has been manipulated.The first goal, behavioral, was to study long…
Regulation of cuticular hydrocarbon profile maturation by Drosophila tanning hormone, bursicon, and its interaction with desaturase activity
2016
International audience; Shortly after emergence the exoskeleton (cuticle) of adult insects is rapidly expanded, hardened (sclerotized), and pigmented (melanized). In parallel with this process, the oenocytes, which are large polyploid cells located below the abdominal epidermis, secrete onto the cuticle a cocktail of cuticular hydrocarbons (CHs) and waxes. These improve the waterproofing of the cuticle, and also provide important chemosensory and pheromonal cues linked with gender, age, and species differentiation. The hardening and pigmentation of the new cuticle are controlled by the neurohormone, bursicon, and its receptor, encoded by the DLGR2 receptor, rickets (rk); by contrast, little…
Dietary rescue of altered metabolism gene reveals unexpected [i]Drosophila[/i] mating cues
2015
Running title: Dietary rescue of metabolic mutation and reproduction; To develop and reproduce, animals need long-chain Mono and PolyUnsaturated Fatty Acids (MUFAs; PUFAs). Although some UFAs can be synthesized by the organism, others must be provided by the diet. The gene desat1, involved in Drosophila melanogaster UFA metabolism, is necessary for both larval development and for adult sex pheromone communication. We first characterized desat1 expression in larval tissues. Then, we found that larvae in which desat1 expression was knocked down throughout development died during the larval stages when raised on standard food. By contrast pure MUFAs or PUFAs, but not saturated FAs, added to th…