Search results for "cerebral"

showing 10 items of 1357 documents

Computer Vision Interaction for People with Severe Movement Restrictions

2006

In this paper we present the starting point of research in applying humancomputer interaction (HCI) techniques to help people with cerebral palsy to use computers via vision-based interaction. Our work includes the development and improvement of visionbased assistive technology, which was tested in experiments with cerebral palsy users. A brief review of current assistive technologies for severely physically impaired people and an explanation of the developed applications of such technologies are also presented. The final part of the paper describes the experimentation goals, process, and preliminary results. Future work directions are also indicated.

cerebral palsycomputer vision interactionhuman-computer interactiondesign for allComputingMilieux_COMPUTERSANDSOCIETYphysically disabled usersaccessibility
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Neurological Screening in Elderly Liver Transplantation Candidates: A Single Center Experience.

2022

Background: Cerebral small vessels disease (cSVD) is an age-related disorder and risk factor for stroke and cognitive/motor impairments. Neurological complications (NCs) are among the causes of adverse outcomes in older liver transplant recipients. This study sought to determine whether cSVD predicts acute NCs in over 65-year-old liver transplant patients. Methods: Data were collected, from a retrospective medical chart review, of 22 deceased donor liver transplant recipients aged 65 years or older with a pre-operative brain magnetic resonance imaging (MRI). We used the Fazekas score (0–3) as a quantitative measurement of the vascular lesion load seen in the MRI. We analyzed all post-operat…

cerebral small vessel disease; liver transplantation; brain magnetic resonance imaging elderly age-related diseasesLiver transplantationCerebral small vessel diseaseNeurology (clinical)Brain magnetic resonance imaging elderly age-related diseasesNeurology international
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Autologous fibrin sealant (Vivostat(®)) in the neurosurgical practice: Part I: Intracranial surgical procedure.

2014

Background: Hemorrhages, cerebrospinal fluid (CSF) fistula and infections are the most challenging postoperative complications in Neurosurgery. In this study, we report our preliminary results using a fully autologous fibrin sealant agent, the Vivostat ® system, in achieving hemostasis and CSF leakage repair during cranio‑cerebral procedures. Methods: From January 2012 to March 2014, 77 patients were studied prospectively and data were collected and analyzed. Autologous fibrin sealant, taken from patient’s blood, was prepared with the Vivostat ® system and applied on the resection bed or above the dura mater to achieve hemostasis and dural sealing. The surgical technique, time to bleeding c…

cerebrospinal fistulamedicine.medical_specialtyDura materFistuladura materAutologous fibrin glue; Cerebral hemorrhage; Cerebrospinal fistula; Dura mater; Skull base copyright; Surgery; Neurology (clinical)FibrinCerebrospinal fluidmedicineFibrin gluecerebral hemorrhagebiologybusiness.industrySkull base copyrightSettore MED/27 - NeurochirurgiaSealantskull basemedicine.diseaseSurgerymedicine.anatomical_structureHemostasisbiology.proteinAutologous fibrin glueSurgeryOriginal ArticleNeurosurgeryNeurology (clinical)businessSurgical neurology international
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Quantification of intracranial contribution to rheoencephalography by a numerical model of the head

2000

Abstract Objectives : Partial contributions of intracranial and extracranial circulation to rheoencephalography (REG) remain uncertain. The main goal of this work is to determine theoretically the capability of REG techniques to reflect intracranial blood flow. Methods : Head and current injection electrodes were computationally modeled to assess REG sensitivity to brain and scalp conductivity changes. Data obtained were related to tissue perfusions to calculate the partial contribution of cerebral blood perfusion to REG I, REG II and monopolar REG and to assess their amplitudes. Results : When REG I and monopolar REG were used, the theoretical maximum of intracranial contribution was reach…

chemical and pharmacologic phenomenaModels BiologicalSensitivity and SpecificityRheoencephalographyimmune system diseaseshemic and lymphatic diseasesPhysiology (medical)HumansComputer SimulationPlethysmography ImpedanceElectrodesPhysicsMeasurement methodbusiness.industryElectric ConductivityBrainElectroencephalographyhemic and immune systemsBlood flowSensory SystemsNeurologyCerebral blood flowCerebrovascular CirculationAnesthesiaRegression AnalysisNeurology (clinical)Nuclear medicinebusinessHeadClinical Neurophysiology
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The Influence of Oxygen Affinity of Blood and Cerebral Blood Flow on Cerebral Oxygen Supply

1969

The quantity of oxygen transported, per unit of time, by the blood to the brain, is determined by the blood flow, the oxygen capacity, and the oxygen affinity of the blood. The O2-exchange between the blood and the tissue cells depends mainly on the oxygen transport characteristics of the blood and the O2 diffusion conditions in the blood and tissue.

chemistryCerebral blood flowDiffusionBiophysicsOxygen transportchemistry.chemical_elementAcid–base homeostasisBlood flowCerebral oxygenOxygen affinityOxygen
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Brain Nucleotides and Excitatory Processes

1971

The trivial analogy in the structure of barbiturates and pyrimidines has suggested a series of studies, which were undertaken in our Laboratory since 1961 (Bonavita et al., 1960 to investigate on the role of some free nucleotides in cerebral activity.

chemistry.chemical_classificationCerebral activityChemistryExcitatory postsynaptic potentialNucleotideNeuroscience
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In vivo analysis of noise dependent activation of white blood cells and microvascular dysfunction in mice

2021

This article contains supporting information on data collection for the research article entitled “Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice” by Eckrich et al. We found that noise-induced stress triggered microvascular dysfunction via involvement of innate immune-derived reactive oxygen species. In this article, we present the instrumentation of mice with dorsal skinfold chambers for in vivo microscopic imaging of blood flow, interaction of leukocytes with the vascular wall (also by fluorescent labelling of blood cells) and vessel diameter. In addition, we explain the preparation of cerebral arterioles for measurement of…

chemistry.chemical_classificationReactive oxygen speciesPathologymedicine.medical_specialtyScienceQClinical BiochemistryIn vivo analysisVideo microscopyBlood flowMethod ArticleIn vivo fluorescence microscopy and cerebral arteriole cannulation to assess noise induced changes in activation of white blood cells and microvascular dysfunctionIn vitroCerebral arterioles cannulationMedical Laboratory TechnologyDorsal skinfold chamberchemistryIn vivoFluorescent labeling of blood cellsVideo microscopyMicroscopic imagingmedicineResearch articleMethodsX
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Molecular Evolution of Lactate Dehydrogenase in the Developing Nervous Tissue*

1964

Publisher Summary This chapter describes both electrophoretic and catalytic studies on lactate dehydrogenase (LDH) in the developing brain. It has been found that the enzyme exhibits at birth a composition that gradually changes to attain the final pattern observed in the adult. The neurochemical findings on LDH isozymes parallel the rapid growth in the first days after birth. Isozyme E, which is not present in detectable amounts 2 days after birth, represents 15% of the enzyme on the 22nd day. Similarly, the percentage decrease of isozyme B is quite steep at the beginning. Nevertheless, the final pattern is attained only at the end of the 2nd month that is, when the cerebral cortex is full…

chemistry.chemical_classificationmedicine.medical_specialtyChemistryNervous tissueIsozymeDiencephalonchemistry.chemical_compoundmedicine.anatomical_structureNeurochemicalEndocrinologyEnzymeBiochemistryMolecular evolutionCerebral cortexInternal medicineLactate dehydrogenasemedicine
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Differential antiepileptic effects of the organic calcium antagonists verapamil and flunarizine in neurons of organotypic neocortical explants from n…

1988

Effects of the organic calcium antagonists verapamil and flunarizine on pentylenetetrazol induced paroxysmal depolarizations were tested in organotypic neocortical explants taken from neonatal rats. In these in vitro experiments the papaverin derivative verapamil depressed, and finally abolished, epileptic discharges in all cases. The piperazine derivative flunarizine, however, which is known to suppress epileptic discharges in hippocampal CA3 neurons (Bingmann and Speckmann 1986), showed no significant antiepileptic effects in the explanted neocortical neurons. Thus, the present findings may indicate that the suppressive action of flunarizine on the generation of paroxysmal depolarizations…

chemistry.chemical_elementNeocortexCalciumPharmacologyHippocampal formationMembrane PotentialsOrgan Culture TechniquesSeizuresMedicineAnimalsPentylenetetrazolFlunarizineMembrane potentialCerebral CortexNeuronsEpilepsyNeocortexbusiness.industryGeneral NeuroscienceNewbornRatsmedicine.anatomical_structurechemistryAnimals NewbornVerapamilCerebral cortexCalcium antagonistsVerapamilPentylenetetrazolebusinessNeuroscienceFlunarizinemedicine.drugExperimental Brain Research
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Number Representation in Bilinguals. The role of early learning in the Mental Number Line representation

2016

La presente tesis tiene como objetivo el estudio de la matemática bilingüe dentro del ámbito científico de la Cognición Numérica y Bilingüismo. El abordaje de cómo las personas bilingües representan y acceden a la magnitud es actualmente una cuestión de creciente interés que responde a la necesidad de entender el papel que desempeña el lenguaje en la adquisición temprana de las matemáticas. Esa importancia se ve reflejada habitualmente en el contexto de la educación, en donde el aprendizaje de la aritmética y el bilingüismo concurren de forma natural. Dada la importancia que tiene en nuestra sociedad tanto la adquisición de las matemáticas como el aprendizaje de una segunda lengua en edades…

cognición numérica:LINGÜÍSTICA [UNESCO]:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍAseñal cerebralUNESCO::LINGÜÍSTICAbilingüismoneurociencia cognitiva y educación
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