Search results for "cervical"

showing 10 items of 511 documents

Cortical bone thickening in Type A posterior atlas arch defects: experimental report.

2017

Abstract Background Context To date, no information about the cortical bone microstructural properties in atlas vertebrae with posterior arch defects has been reported. Purpose To test if there is an increased cortical bone thickening in atlases with Type A posterior atlas arch defects in an experimental model. Study Design Micro-computed tomography (CT) study on cadaveric atlas vertebrae. Methods We analyzed the cortical bone thickness, the cortical volume, and the medullary volume (SkyScan 1172 Bruker micro-CT NV, Kontich, Belgium) in cadaveric dry vertebrae with a Type A atlas arch defect and normal control vertebrae. Results The micro-CT study revealed significant differences in cortica…

MaleMedullary cavityeducation03 medical and health sciences0302 clinical medicineCadaverAtlas (anatomy)medicineCadaverCortical BoneHumansOrthopedics and Sports MedicineCervical AtlasAtlas archAged030222 orthopedicsbusiness.industryAnatomyX-Ray MicrotomographyMiddle Agedmusculoskeletal systemmedicine.anatomical_structureSurgeryCortical boneNeurology (clinical)ThickeningTomographyCadaveric spasmbusinessTomography X-Ray Computed030217 neurology & neurosurgeryThe spine journal : official journal of the North American Spine Society
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Malignant teratoma in Klippel-Feil syndrome: a case report and review of the literature

2015

Introduction: Klippel-Feil syndrome is characterized by a congenital fusion of cervical vertebrae. Intracranial teratomas are nongerminomatous germ cell tumors and they account for 0.3 to 0.9% of all intracranial tumors. Teratomas with malignant transformation refer to lesions which give rise to malignant cancer of somatic type. The association between tumors of dermoid origin and Klippel-Feil malformation is extremely rare. Only 23 other cases have so far been reported, and only one case of dermoid tumor with areas of dedifferentiation on squamous cell carcinoma has been described. Case presentation: We report the case of a 72-year-old white man with a 2-year history of gait and balance di…

MalePathologymedicine.medical_specialtyVertebral arteryKlippel–Feil syndromeCase ReportKlippel-Feil syndromeFourth ventricleKlippel–Feil syndromeMalignant transformationCervical spine Dermoid tumor Klippel–Feil syndrome Pathology Posterior fossa TeratomaPosterior fossamedicine.arteryCervical spinemedicinePathologyHumansAgedDermoid CystMedicine(all)medicine.diagnostic_testbusiness.industryCervical spine; Dermoid tumor; Klippel-Feil syndrome; Pathology; Posterior fossa; Teratoma; Aged; Cervical Vertebrae; Cranial Fossa Posterior; Dermoid Cyst; Gait Apraxia; Humans; Klippel-Feil Syndrome; Magnetic Resonance Imaging; Male; Teratoma; Tomography X-Ray Computed; Treatment Outcome; Medicine (all)Medicine (all)TeratomaMagnetic resonance imagingGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingGait ApraxiaTreatment OutcomeDermoid cystCranial Fossa PosteriorCervical VertebraeGerm cell tumorsTeratomabusinessTomography X-Ray ComputedDermoid tumorHuman
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Discover cervical disc arthroplasty versus anterior cervical discectomy and fusion in symptomatic cervical disc diseases: A meta-analysis.

2016

OBJECTIVE:Symptomatic cervical disc disease (SCDD) is a common degenerative disease, and Discover artificial cervical disc, a new-generation nonconstrained artificial disk, has been developed and performed gradually to treat it. We performed this meta-analysis to compare the efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) for SCDD. METHODS:An exhaustive literature search of PubMed, EMBASE, and the Cochrane Library was conducted to identify randomized controlled trials that compared DCDA with ACDF for patients suffering SCDD. A random-effect model was used. Results were reported as standardized mean difference or risk …

MalePhysiologymedicine.medical_treatmentSensory Physiologylcsh:MedicineAnterior cervical discectomy and fusionIntervertebral Disc DegenerationCochrane LibraryOssificationlaw.invention0302 clinical medicineMathematical and Statistical TechniquesRandomized controlled triallawMedicine and Health SciencesRange of Motion Articularlcsh:ScienceIntervertebral DiscRandomized Controlled Trials as Topic030222 orthopedicsProstheticsMultidisciplinaryMiddle AgedSensory SystemsTreatment OutcomeSomatosensory SystemResearch DesignMeta-analysisPhysical SciencesCervical VertebraeFemaleBone RemodelingRange of motionIntervertebral Disc DisplacementStatistics (Mathematics)DiskectomyResearch ArticleBiotechnologyAdultmedicine.medical_specialtyDrug Research and DevelopmentClinical Research DesignSurgical and Invasive Medical ProceduresResearch and Analysis MethodsArthroplasty03 medical and health sciencesMusculoskeletal System ProceduresmedicineHumansClinical TrialsStatistical MethodsPharmacologybusiness.industrylcsh:RBiology and Life SciencesPain SensationArthroplastyRandomized Controlled TrialsSurgeryAssistive TechnologiesStrictly standardized mean differenceRelative risklcsh:QMedical Devices and EquipmentAdverse EventsClinical MedicinebusinessPhysiological Processes030217 neurology & neurosurgeryMathematicsMeta-AnalysisNeurosciencePloS one
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The Qualification of Outcome after Cervical Spine Surgery by Patients Compared to the Neck Disability Index

2016

Contains fulltext : 168196.PDF (Publisher’s version ) (Open Access) OBJECTIVE: The Neck Disability Index (NDI) is a patient self-assessed outcome measurement tool to assess disability, and that is frequently used to evaluate the effects of the treatment of neck-related problems. In individualized medicine it is mandatory that patients can interpret data in order to choose a treatment. A change of NDI or an absolute NDI is generally meaningless to a patient. Therefore, a correlation between the qualification of the clinical situation rated by the patient and the NDI score was evaluated. METHODS: Patients who completed an NDI after anterior surgery because of symptomatic single level degenera…

MaleQuestionnairesCervical spine surgeryMedical DoctorsHealth Care ProvidersStress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13]Social Scienceslcsh:MedicineSeverity of Illness IndexOutcome (game theory)Disability EvaluationCognition0302 clinical medicineSociologyQuality of lifeSurveys and QuestionnairesMedicine and Health SciencesEthnicitiesPostoperative Periodlcsh:SciencePain Measurement030222 orthopedicsMultidisciplinaryMortality rateWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]ProfessionsAnterior surgerymedicine.anatomical_structureResearch DesignPreoperative PeriodCervical VertebraeFemaleResearch ArticleCervical vertebraemedicine.medical_specialtyPatientsDeath RatesDecision MakingSurgical and Invasive Medical ProceduresResearch and Analysis MethodsEducation03 medical and health sciencesPopulation MetricsPhysiciansSeverity of illnessmedicineHumansEducational AttainmentDemographyDutch PeopleSurvey ResearchPopulation Biologybusiness.industrylcsh:RBiology and Life SciencesPatient Outcome AssessmentHealth CareReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]ROC CurvePeople and PlacesQuality of LifePhysical therapyCognitive SciencePopulation Groupingslcsh:Qbusiness030217 neurology & neurosurgeryNeck Disability IndexNeuroscience
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A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis

1987

In a long-term multicenter open trial involving 10 general practitioners, the efficacy and tolerance of S-adenosylmethionine (SAMe) were studied for 24 months in 108 patients with osteoarthritis of the knee, hip, and spine. At the end of the 24-month observation period, 97 of the patients were still in the study. The patients received 600 mg of SAMe daily (equivalent to three tablets of 200 mg each) for the first two weeks and thereafter 400 mg daily (equivalent to two tablets of 200 mg each) until the end of the 24th month of treatment. Separate evaluations were made for osteoarthritis of the knee, hip, cervical spine, and dorsal/lumbar spine. The severity of the clinical symptoms (morning…

MaleS-Adenosylmethioninemedicine.medical_specialtyClinical effectivenessOsteoarthritisOsteoarthritisHumansMedicineLongitudinal StudiesAdverse effectAgedClinical Trials as TopicPsychological TestsDepressionbusiness.industryAnti-Inflammatory Agents Non-SteroidalMorning stiffnessGeneral MedicineMiddle Agedmedicine.diseaseCervical spineSurgeryClinical trialFemaleLumbar spineOpen labelbusinessThe American Journal of Medicine
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Vaccination against HPV-Associated Neoplasias

2014

Neoplasias associated with anogenital human papilloma viruses (HPV) are characterised by high patient morbidity and mortality and by appreciable limitations in the patientʼs quality of life. Each year 530,000 women worldwide and 4800 women in Germany develop cervical cancer 1, 2. Biomolecular and epidemiological studies carried out in the past 25 years have demonstrated causal link between persisting infections with HPV 16 and HPV 18 and at least 11 other so-called high-risk HPVs (HR-HPVs) and the development of cervical cancer and its precursor lesions (so-called dysplasias or, respectively, cervical intraepithelial neoplasias – CIN). HPV 16, HPV 18 and other HR-HPVs are also the causes of…

MaleSexually transmitted diseasemedicine.medical_specialtyGenital Neoplasms FemaleImmunization SecondaryMedizinHPV vaccinesGermanyMaternity and MidwiferymedicineHumansPenile cancerPapillomavirus VaccinesCervixGynecologyCervical cancerDose-Response Relationship Drugbusiness.industryPapillomavirus Infectionsvirus diseasesObstetrics and GynecologyGuidelinemedicine.diseaseDermatologyfemale genital diseases and pregnancy complicationsVaccinationmedicine.anatomical_structureGenital Neoplasms MaleFemaleSkin cancerbusiness
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Incidence and outcome of cerebrovascular events related to cervical artery dissection: the Dijon Stroke Registry.

2013

Background Reliable epidemiological data on the true incidence of cerebrovascular events related to spontaneous cervical artery dissection, including stroke and transient ischemic attack, are scarce. Aims To evaluate the incidence, characteristics, and outcome of cerebrovascular events due to cervical artery dissection. Methods All cerebrovascular events (stroke and transient ischemic attack) occurring in Dijon, France, from 2006 to 2011, were retrieved from a population-based registry. Patients with a cervical artery dissection were identified. Incidence rates, baseline characteristics, and outcome at three-months were described. Results Among the 1368 patients with cerebrovascular events,…

MaleStroke registrymedicine.medical_specialtyCervical ArteryVertebral artery dissectionDissection (medical)Carotid Artery Internal DissectionInternal medicineEpidemiologymedicineHumansRegistriesStrokeAcute strokeVertebral Artery Dissectionbusiness.industryIncidence (epidemiology)IncidenceMiddle Agedmedicine.diseaseStrokeNeurologyIschemic Attack TransientCardiologyFemaleRadiologyFrancebusinessInternational journal of stroke : official journal of the International Stroke Society
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Nitric oxide synthase neurons in the rodent spinal cord: distribution, relation to Substance P fibers, and effects of dorsal rhizotomy.

2001

The indirect immunofluorescent method was employed to investigate the distribution of neuronal nitric oxide synthase-like immunoreactivity(nNOS-LI) in the spinal cord of the golden hamster and to compare it to data obtained from rats. Immunoreactive neurons were found throughout the cervico-sacral extent in the dorsal horn (mainly in laminae I-III) and in the preganglionic autonomic regions, i.e., the sympathetic intermediolateral nucleus (IML), lateral funicle (LF), intercalated region (IC), the area surrounding the central canal (CA), and the sacral preganglionic parasympathetic cell group. While the distribution of immunoreactive cells was generally similar in both species, some differen…

MaleSuperior cervical ganglionAutonomic Fibers PreganglionicPopulationHamsterNitric Oxide Synthase Type ISubstance PRhizotomyRats Sprague-DawleyCellular and Molecular NeuroscienceNerve FibersCricetinaemedicineAnimalseducationNeuronseducation.field_of_studybiologyMesocricetusChemistryIntermediolateral nucleusAnatomySpinal cordbiology.organism_classificationImmunohistochemistryRatsPerfusionmedicine.anatomical_structurenervous systemSpinal CordAxoplasmic transportNitric Oxide SynthaseMesocricetusGolden hamsterJournal of chemical neuroanatomy
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Calcitonin gene-related peptide-like immunoreactivity in spinal cord and superior cervical ganglion of the djungarian hamster (Phodopus sungorus)

1993

The indirect immunofluorescent method was employed to investigate the distribution of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) in the spinal cord and superior cervical ganglion of the Djungarian hamster Phodopus sungorus. In cross-sections of the spinal cord, immunoreactive fibres and terminals were found in laminae 1 and 2 in high density, in the dorsolateral (Lissauer's) tract, in ventral and lateral horns, and in the area surrounding the central canal. A few CGRP-LI perikarya were seen in the ventral but not the dorsal horn. CGRP-LI was further observed in preganglionic sympathetic neurons which were labelled by retrograde axonal transport of fluoro-gold (FG) follo…

MaleSuperior cervical ganglionPhodopusStilbamidinesAutonomic Fibers PreganglionicCalcitonin Gene-Related PeptideHamsterSuperior Cervical GanglionCalcitonin gene-related peptideBiologyCellular and Molecular NeuroscienceSympathetic Fibers PostganglionicCricetinaemedicineAnimalsFluorescent DyesIntermediolateral nucleusAnatomySpinal cordImmunohistochemistryCircadian RhythmGanglionmedicine.anatomical_structureSpinal Cordnervous systemCervical gangliaLateral funiculusJournal of Chemical Neuroanatomy
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Nitric oxide synthase-immunoreactive vagal afferent fibers in rat superior cervical ganglia

1995

Abstract Chronic (5–14 days) preganglionic denervation of the rat superior cervical ganglia by sectioning the cervical sympathetic trunk resulted in a time-related partial or complete loss of nitric oxide synthase (isoform I)-immunoreactive fibers and terminals surrounding many sympathetic ganglionic neurons. Unexpectedly, denervation unmasked many varicose nitric oxide synthase-immunoreactive fibers, some of which could be traced the entire length of the superior cervical ganglia. Injection of the retrograde tracer Fluorogold into the superior cervical ganglia labeled a population of nodose ganglion cells and of dorsal root ganglion cells from C8 to T3 segments. When the same sections were…

MaleSuperior cervical ganglionSympathetic nervous systemPopulationSuperior Cervical GanglionNitric oxideRats Sprague-Dawleychemistry.chemical_compoundDorsal root ganglionmedicineAnimalseducationDenervationAfferent Pathwayseducation.field_of_studyChemistryGeneral NeuroscienceVagus NerveNodose GanglionAnatomyImmunohistochemistryRatsmedicine.anatomical_structureCervical gangliaFemaleNodose GanglionAmino Acid OxidoreductasesNitric Oxide SynthaseNeuroscience
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