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RESEARCH PRODUCT
Discover cervical disc arthroplasty versus anterior cervical discectomy and fusion in symptomatic cervical disc diseases: A meta-analysis.
Zhuojing LuoZhe WangYu TangYue ZhouLei ShangguanLei ShangguanGuang-zhi NingGuang-zhi Ningsubject
MalePhysiologymedicine.medical_treatmentSensory Physiologylcsh:MedicineAnterior cervical discectomy and fusionIntervertebral Disc DegenerationCochrane LibraryOssificationlaw.invention0302 clinical medicineMathematical and Statistical TechniquesRandomized controlled triallawMedicine and Health SciencesRange of Motion Articularlcsh:ScienceIntervertebral DiscRandomized Controlled Trials as Topic030222 orthopedicsProstheticsMultidisciplinaryMiddle AgedSensory SystemsTreatment OutcomeSomatosensory SystemResearch DesignMeta-analysisPhysical SciencesCervical VertebraeFemaleBone RemodelingRange of motionIntervertebral Disc DisplacementStatistics (Mathematics)DiskectomyResearch ArticleBiotechnologyAdultmedicine.medical_specialtyDrug Research and DevelopmentClinical Research DesignSurgical and Invasive Medical ProceduresResearch and Analysis MethodsArthroplasty03 medical and health sciencesMusculoskeletal System ProceduresmedicineHumansClinical TrialsStatistical MethodsPharmacologybusiness.industrylcsh:RBiology and Life SciencesPain SensationArthroplastyRandomized Controlled TrialsSurgeryAssistive TechnologiesStrictly standardized mean differenceRelative risklcsh:QMedical Devices and EquipmentAdverse EventsClinical MedicinebusinessPhysiological Processes030217 neurology & neurosurgeryMathematicsMeta-AnalysisNeurosciencedescription
OBJECTIVE:Symptomatic cervical disc disease (SCDD) is a common degenerative disease, and Discover artificial cervical disc, a new-generation nonconstrained artificial disk, has been developed and performed gradually to treat it. We performed this meta-analysis to compare the efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) for SCDD. METHODS:An exhaustive literature search of PubMed, EMBASE, and the Cochrane Library was conducted to identify randomized controlled trials that compared DCDA with ACDF for patients suffering SCDD. A random-effect model was used. Results were reported as standardized mean difference or risk ratio with 95% confidence interval. RESULTS:Of 33 articles identified, six studies were included. Compared with ACDF, DCDA demonstrated shorter operation time (P 0.05). Subgroup analyses did not demonstrated significant differences. CONCLUSION:In conclusion, DCDA presented shorter operation time, and better ROM at the operative level. However, no significant differences were observed in blood loss, NDI scores, neck and arm pain scores, JOA scores, secondary surgery procedures and adverse events between the two groups. Additionally, more studies of high quality with mid- to long-term follow-up are required in future.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-12-04 | PloS one |