Search results for "challenge"
showing 10 items of 181 documents
Testosterone levels and their associations with lifetime number of opposite sex partners and remarriage in a large sample of American elderly men and…
2011
Testosterone (T) has been argued to modulate mating and parenting behavior in many species, including humans. The role of T for these behaviors has been framed as the challenge hypothesis. Following this hypothesis, T should be positively associated with the number of opposite sex partners a male has. Indeed research in humans has shown that T is positively related to the number of opposite sex partners a young man has had. Here we test, in both men and women, whether this relationship extends to the lifetime number of sex partners. We also explored whether or not T was associated with current marital status, partnership status and whether or not the participant remarried. Using a large sam…
To be a trained and supported volunteer in palliative care – a phenomenological study
2017
Background: It has been found that including volunteers in palliative care is a positive contribution to seriously ill patients. It is, however, recommended that the volunteers are trained and supported. The aim of this study was to describe a group of trained and supported volunteers’ lived experiences as volunteers in palliative care within the community health care services. Methods: This study adopted a descriptive phenomenological approach featuring individual interviews with nine volunteers. The interviews were analysed using the descriptive phenomenological research method according to Giorgi. Results: Being a volunteer in palliative care was both a positive and meaningful experience…
Individual variability of mytimycin gene expression in mussel
2012
The antifungal peptide mytimycin (MytM) is synthesized by hemocytes of the Mediterranean mussel, Mytilus galloprovincialis. In addition to sequence and gene structure diversities previously reported from pooled hemocytes, the present report focused on the expression of mytm gene in individual M. galloprovincialis, before and after challenge. Within untreated mussel, MytM mRNA was observed by ISH in about 42% of circulating hemocytes, characterized by large, diffuse nucleus. Injection with Fusarium oxysporum increased such percentage, but in only some of the mussels. Similarly, MytM gene expression increased after injection in only some of the mussels, as measured by qPCR. Responders and not…
Opportunities and Challenges to Microbial Symbiosis Research in the Microbiome Era
2020
Peer reviewed
Digital interventions on healthy lifestyle management: Systematic review
2021
Background Digital interventions have tremendous potential to improve well-being and health care conveyance by improving adequacy, proficiency, availability, and personalization. They have gained acknowledgment in interventions for the management of a healthy lifestyle. Therefore, we are reviewing existing conceptual frameworks, digital intervention approaches, and associated methods to identify the impact of digital intervention on adopting a healthier lifestyle. Objective This study aims to evaluate the impact of digital interventions on weight management in maintaining a healthy lifestyle (eg, regular physical activity, healthy habits, and proper dietary patterns). Methods We conducted …
Old mathematical challenges: Precedents to the millennium problems
2018
The millennium problems set out by the Clay Mathematics Institute became a stimulus for mathematical research. The aim of this article is to highlight some previous challenges that were also a stimulus to finding proof for some interesting results. With this pretext, we present three moments in the history of mathematics that were important for the development of new lines of research. We briefly analyse the Tartaglia challenge, which brought about the discovery of a formula for third degree equations; Johan Bernoulli?s problem of the curve of fastest descent, which originated the calculus of variations; and the incidence of the problems posed by David Hilbert in 1900, focusing on the first…
AIF-1 and RNASET2 are involved in the inflammatory response in the Mediterranean mussel Mytilus galloprovincialis following Vibrio infection
2022
Filter-feeding bivalves, such as the Mytilus species, are exposed to different types of bacteria in the surrounding waters, in particular of the Vibrio genus. Mussels lack an adaptive immune system and hemocytes can recognize pathogen-associated molecular patterns (PAMPs) via pattern recognition receptors (PRRs) to activate intracellular signaling pathways to trigger the antimicrobial effectors synthesis. Among the areas of bivalve immunity that deserve study include the role of hemocyte subpopulations. Since little information are available on immune responses at the tissue level to human pathogenic vibrios commonly detected in coastal waters involved in seafood-borne diseases, in this wor…
Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity.
2012
Non-Celiac Wheat Sensitivity Diagnosed by Double-Blind Placebo-Controlled Challenge: Exploring a New Clinical Entity
A Planning and Control System for Self-Driving Racing Vehicles
2018
Autonomous robots will soon enter our everyday life as self-driving cars. These vehicles are designed to behave according to certain sets of cooperative rules, such as traffic ones, and to respond to events that might be unpredictable in their occurrence but predictable in their nature, such as a pedestrian suddenly crossing a street, or another car losing control. As civilian autonomous cars will cross the road, racing autonomous cars are under development, which will require superior Artificial Intelligence Drivers to perform in structured but uncertain conditions. We describe some preliminary results obtained during the development of a planning and control system as key elements of an A…
Exploring the relationships between high involvement work system practices, work demands and emotional exhaustion: a multi-level study.
2016
This study explores the impact of enacted high involvement work systems (HIWS) practices on employee emotional exhaustion. This study hypothesized that work overload and job responsibility mediate the relationship between HIWS practices (ability, motivation, opportunity and work design HIWS practices) and employee emotional exhaustion. A total of 360 employees (nested within 49 work units) rated their feelings of work overload, job responsibility and emotional exhaustion. The line managers from these work units rated the enacted HIWS practices. Results indicate that ability- and motivation HIWS practices are positively related to work overload, and ability-, motivation- and work design HIWS…