Search results for "chronic"
showing 10 items of 3309 documents
Perception of family-system and parental competence in mothers of children suffering from chronic heart disease
2009
Choroidal thickness is associated with renal hemodynamics in essential hypertension
2020
The choroid is the most vascularized structure of the eye and plays a central role in the development of the retinal vascular changes that occur in arterial hypertension. Changes of choroidal thickness (ChT) assessed by optical coherence tomography (OCT) technology could reflect the vascular complications of hypertension. Also, intrarenal hemodynamic damage, associated with endothelial dysfunction, demonstrated to be a good indicator of systemic morphofunctional arterial impairment. The aim of this study is to assess the relationship between ChT and renal hemodynamics in subjects with essential hypertension. Routine laboratory tests, clinical history, and physical examination, including blo…
Clinical history of thrombosis before diagnosis of overt myeloproliferative neoplasms in triple negative patients
2017
Thromboses are the most important preventable risk factors for morbidity and mortality in myeloproliferative neoplasms (MPN). We here performed a retrospective cross sectional study of patients with a diagnosis of Philadelphia negative MPN and a prior history of thrombosis, analyzed from electronic charts. Among a cohort of 260 patients with MPNs (78PV, 102ET, 80 MF), forty four were found triple negative for JAK-2, calreticulin and MPL gene mutations. Sixty-nine (26.54%) patients (29F, 40M) had a personal past clinical history of arterial or venous thrombosis. Among patients with thrombosis, 13(18.8%) cases (11ET, 2MF) were triple negative (median age:60 years). Most events, in particular …
Neck liymph nodes in chronic autoimmune thyroiditis: the sonographic pattern.
2013
An overview of randomized controlled trials on endovascular treatment for chronic cerebrospinal venous insufficiency in multiple sclerosis patients
2021
About ten years ago it was hoped that venous angioplasty for abnormal veins, primarily the internal jugular veins, will be a much awaited treatment for multiple sclerosis. Yet, a majority of randomized clinical trials on endovascular treatment for chronic cerebrospinal venous insufficiency did not reveal clinical efficacy of these procedures in multiple sclerosis patients. Still, a detailed analysis of these trials suggests that they were poorly designed, underpowered and endovascular techniques used were often far from being optimal. Nonetheless, even considering weak points of these trials, it can be concluded that venous angioplasty should not be used as a routine treatment modality in m…
Risk stratification tools to predict future hospital admissions in elderly people. Application, development and implementation in the Valencian Healt…
2017
La presente tesis se enmarca en un escenario caracterizado por una población que cada vez vive más años y en la que el porcentaje de personas mayores es progresivamente más alto. De forma adicional, el aumento de la prevalencia de las enfermedades crónicas (EC) supone un importante impacto sobre los sistemas sanitarios dado que éstas son la principal causa de muerte a nivel mundial y, en muchos casos, están asociadas a situaciones de dependencia y a la necesidad de cuidados de larga duración. Con el objetivo de llevar a cabo un abordaje más efectivo de las enfermedades asociadas al envejecimiento y a la cronicidad los sistemas asistenciales deberían sufrir un cambio de paradigma en el que s…
Precision Medicine for Chronic Diseases: Focus on Lifestyle Changes
2022
Virtually all chronic diseases are sustained by lifestyle factors [...]
DYSPHORIC-LIKE BEHAVIOUR DURING ETHANOL WITHDRAWAL IN FEMALE RATS. EFFECT OF CONTINUOUS VS INTERMITTENT ACCESS PARADIGM.
2014
Women show higher vulnerability for neuroadaptation to alcohol, which may contribute to negative emotional state during withdrawal (Sharrett-Field et al., 2013; Koob and Le Moal, 1997). This study aimed at exploring the effects of different patterns of voluntary ethanol consumption on female rat"s affective behaviour during withdrawal. Female rats underwent 12-week-, 2-bottle choice- continuous or intermittent (3 days/week ) access to 20% ethanol and were respectively named CARs and IARs. They were tested for alcohol preference; dysphoric-like state during withdrawal (24-48h); depressive- and anhedonic-like behaviours explored by forced swim- and saccharin preference tests; anxiety-like beh…