Search results for "circular"
showing 10 items of 856 documents
Targeting G-quadruplexes with Organic Dyes: Chelerythrine–DNA Binding Elucidated by Combining Molecular Modeling and Optical Spectroscopy
2019
The DNA-binding of the natural benzophenanthridine alkaloid chelerythrine (CHE) has been assessed by combining molecular modeling and optical absorption spectroscopy. Specifically, both double-helical (B-DNA) and G-quadruplex sequences&mdash
Polycationic Monomeric and Homodimeric Asymmetric Monomethine Cyanine Dyes with Hydroxypropyl Functionality—Strong Affinity Nucleic Acids Binders
2021
New analogs of the commercial asymmetric monomethine cyanine dyes thiazole orange (TO) and thiazole orange homodimer (TOTO) with hydroxypropyl functionality were synthesized and their properties in the presence of different nucleic acids were studied. The novel compounds showed strong, micromolar and submicromolar affinities to all examined DNA ds-polynucleotides and poly rA–poly rU. The compounds studied showed selectivity towards GC-DNA base pairs over AT-DNA, which included both binding affinity and a strong fluorescence response. CD titrations showed aggregation along the polynucleotide with well-defined supramolecular chirality. The single dipyridinium-bridged dimer showed intercalatio…
Enzyme-assisted extraction of anthocyanins and other phenolic compounds from blackcurrant (Ribes nigrum L.) press cake: From processing to bioactivit…
2022
The effects of commercial enzymes (pectinases, cellulases, beta-1-3-glucanases, and pectin lyases) on the recovery of anthocyanins and polyphenols from blackcurrant press cake were studied considering two solid:solvent ratios (1:10 and 1:4 w/v). β-glucanase enabled the recovery of the highest total phenolic content – 1142 mg/100 g, and the extraction of anthocyanins was similar using all enzymes (∼400 mg/100 g). The use of cellulases and pectinases enhanced the extraction of antioxidants (DPPH − 1080 mg/100 g; CUPRAC – 3697 mg/100 g). The freeze-dried extracts presented antioxidant potential (CUPRAC, DPPH), which was associated with their biological effects in different systems: antiviral a…
Multiple Scenario Analysis of Battery Energy Storage System Investment: Measuring Economic and Circular Viability
2022
Circular business models for batteries have been revealed in earlier research to achieve economic viability while reducing total resource consumption of raw materials. The objective of this study is to measure the economic performance of the preferred business model by creating different scenarios comparing second life (spent) and new battery investment for seven different European regions and four energy management strategies. Findings reveal levels of economic ability for a total of 34 scenarios simulated, including direct savings per kWh, a total change in energy costs per year, battery charge/discharge cycles, and comparative breakeven analyses. Regional effects are also measured based …
Dried-fruit shell reuse in green construction and building materials
2023
Bio-architecture is a new way of designing and building in line with the European Green Deal and in light of the circular economy principles. This new green approach is guiding the entire construction life cycle toward eco-sustainability and environmental friendliness, from the beginning to the end of the building process. In addition to the use of environmentally-friendly and high-performance building and construction materials, it is necessary to use new technologies that can reduce the environmental footprint. This paper aims to examine the possible reuse of biological wastes of agricultural origin of the Mediterranean basin, whose massive production generates a number of problems for th…
Biochar Particles Obtained from Agricultural Carob Waste as a Suitable Filler for Sustainable Biocomposite Formulations
2022
In the context of sustainable and circular economy, the recovery of biowaste for sustainable biocomposites formulation is a challenging issue. The aim of this work is to give a new life to agricultural carob waste after glucose extraction carried out by a local factory for carob candy production. A pyrolysis process was carried out on bio-waste to produce biofuel and, later, the solid residual fraction of pyrolysis process was used as interesting filler for biocomposites production. In this work, biochar particles (BC) as a pyrolysis product, after fuels recovery of organic biowaste, specifically, pyrolyzed carobs after glucose extraction, were added on poly(butylene-adipate-co-terephthalat…
Initial indicator analysis of bioethylen production pathways
2018
Abstract Circular economy and bioeconomy factors has driven the economy sectors towards sustainable choices. Chemical industry, as stated by the Joint Research Centre of the European Commission, has a potential to reduce 36 % of the greenhouse gas (GHG) emissions by 2050 [1] mainly linked with introduction of emerging energy technologies. Ethylene, chlorine, ammonia and hydrogen are important chemicals for such reduction as they are the most worldwide produced chemicals (16 % of the total production in 2050 for ethylene, 11 % for chlorine and 6 % for ammonia). Meanwhile planned GHG reduction potential for these chemicals, through introduction of compression and separation technologies, is e…
Non-Coding RNA Networks as Potential Novel Biomarker and Therapeutic Target for Sepsis and Sepsis-Related Multi-Organ Failure.
2022
According to “Sepsis-3” consensus, sepsis is a life-threatening clinical syndrome caused by a dysregulated inflammatory host response to infection. A rapid identification of sepsis is mandatory, as the extent of the organ damage triggered by both the pathogen itself and the host’s immune response could abruptly evolve to multiple organ failure and ultimately lead to the death of the patient. The most commonly used therapeutic strategy is to provide hemodynamic and global support to the patient and to rapidly initiate broad-spectrum empiric antibiotic therapy. To date, there is no gold standard diagnostic test that can ascertain the diagnosis of sepsis. Therefore, once sepsis is suspected, t…
Sunflower Residues-Based Biorefinery: Circular Economy Indicators
2023
Fossil fuel price increases, their uneven distribution, environmental issues from their incineration, and lack of guarantees of their energy security are the main drivers for the development of green energy. Agricultural waste is an abundant resource for energy bioprocessing, which improves the functioning of the circular economy. In this study, the following were used as the main indicators: the share of renewable energy and the benefit from it, the coefficient of cyclical use of biomass, and the reduction in carbon dioxide emissions. The ways in which sunflower waste is applied for energy purposes are emphasized. The highest comprehensive ecological and economic effects are shown to be ac…
Conformational investigation of αβ-dehydropeptides
2009
Solution conformations of three series of model peptides, homochiral Ac-Pro-L-Xaa-NHCH3 and heterochiral Ac-Pro-D-Xaa-NHCH3 (Xaa = Val, Phe, Leu, Abu, Ala) as well as alpha,beta-unsaturated Ac-Pro-delta Xaa-NHCH3 [delta Xaa = delta Val, (Z)-delta Phe, (Z)-delta Leu, (Z)-delta Abu] were investigated in CDCl3 and CH2Cl2 by 1H-, 13C-NMR, and FTIR spectroscopy. NH stretching absorption spectra, solvent shifts delta delta for NH (Xaa) and NHCH3 on going from CDCl3 to (CD3)2SO, diagnostic interresidue proton NOEs, and trans-cis isomer ratios were examined. These studies performed showed the essential difference in conformational propensities between homochiral peptides (L-Xaa) on the one hand and…