Search results for "clinica"

showing 10 items of 38311 documents

The Influence of Film and Storage on the Phenolic and Antioxidant Properties of Red Raspberries (Rubus idaeus L.) cv. Erika

2019

In this paper, the effect of the packaging material and storage method on red raspberries produced at Reggio Calabria (Italy) was studied. For this purpose, the fruits were stored immediately after harvest in different conditions: in the fridge at 1 &deg

0106 biological sciencesAntioxidantPhysiologyDPPHmedicine.medical_treatmentClinical BiochemistrypackagingShelf life01 natural sciencesBiochemistryArticlepost-harvestchemistry.chemical_compound0404 agricultural biotechnologymedicinePolyethylene terephthalateFood scienceMolecular Biologyrubussmall fruitbiologylcsh:RM1-95004 agricultural and veterinary sciencesCell Biologybiology.organism_classificationAscorbic acid040401 food sciencenanoactive filmBlowing a raspberryshelf-lifelcsh:Therapeutics. PharmacologyPETchemistryAnthocyaninRubus010606 plant biology & botanyraspberryAntioxidants
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Stability Studies of Bioactive Compounds from Birch Outer Bark Ethanolic Extracts

2018

The literature survey summarizes information about birch outer bark phytochemical composition and details major components: betulin, betulinic acid, lupeol and ursolic acid. In the practical part of research birch outer bark major component stability against chemical and physical degradation was tested; total phenolic content and the antiradical activity of the degraded and nondegraded ethanolic extracts was studied using UV/VIS spectroscopy; the phytochemical composition of the birch outer bark ethanolic extract was investigated by HPLC-TOF/MS. The study of stability experiments has been carried out, which found that birch outer bark ethanolic extract compounds can be exposed to thermal an…

0106 biological sciencesBetulinChemistryMechanical Engineeringcomplex mixtures030226 pharmacology & pharmacy01 natural sciences03 medical and health scienceschemistry.chemical_compound0302 clinical medicineMechanics of Materialsvisual_artvisual_art.visual_art_mediumOrganic chemistryGeneral Materials ScienceBark010606 plant biology & botanyKey Engineering Materials
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Characterization of MRNP34, a novel methionine-rich nacre protein from the pearl oysters

2012

9 pages; International audience; Nacre of the Pinctada pearl oyster shells is composed of 98% CaCO(3) and 2% organic matrix. The relationship between the organic matrix and the mechanism of nacre formation currently constitutes the main focus regarding the biomineralization process. In this study, we isolated a new nacre matrix protein in P. margaritifera and P. maxima, we called Pmarg- and Pmax-MRNP34 (methionine-rich nacre protein). MRNP34 is a secreted hydrophobic protein, which is remarkably rich in methionine, and which is specifically localised in mineralizing the epithelium cells of the mantle and in the nacre matrix. The structure of this protein is drastically different from those …

0106 biological sciencesBiomineralizationCalcifying mantleMethionine-richMolecular Sequence DataClinical BiochemistryGene ExpressionBiologyMatrix (biology)engineering.materialProteomics010603 evolutionary biology01 natural sciencesBiochemistryLow complexity03 medical and health sciencesPaleontologychemistry.chemical_compoundCalcification PhysiologicMethionineAnimalsAmino Acid SequencePinctada[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsNacre030304 developmental biology0303 health sciencesMethionineViral matrix proteinOrganic ChemistryProteinsEpithelial Cells[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/Biomaterialsbiology.organism_classificationProtein Structure TertiarychemistryBiochemistryengineeringMolluscMatrix proteinPearlBiomineralizationPinctada
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Positive effect of platelet rich fibrin on osseointegration

2016

Background Leukocyte-platelet rich fibrin (L-PRF) is a second generation platelet concentrate clinically used to accelerate tissue healing and bone regeneration. Achieving reduced implant osseointegration time could provide immediate or early loading of implants. The aim of this study was to evaluate the L-PRF-induced osseointegration and bone-implant contact (BIC) in an experimental animal model. Material and Methods Twelve 4-month-old New Zealand white rabbits were used. Following general anesthesia, 3-5 mL of blood was obtained from the central artery in rabbit ear and L-PRF was prepared. Two implant cavities (5 mm long and 3 mm in diameter) were created in each tibia with a total of fou…

0106 biological sciencesBone RegenerationDentistry01 natural sciencesOsseointegrationFibrin03 medical and health sciences0302 clinical medicineOsseointegrationPlatelet-Rich Fibrin010608 biotechnologyEarly loadingAnimalsMedicinePlatelet concentrateBone regenerationMatrix for growth factorsGeneral DentistryDental ImplantsFibrinbiologybusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]digestive system diseasesPlatelet-rich fibrinExperimental animalOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASbiology.proteinSurgeryRabbitsImplantOral SurgerybusinessPlatelet rich fibrinMedicina Oral Patología Oral y Cirugia Bucal
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The roles of whole-genome and small-scale duplications in the functional specialization of Saccharomyces cerevisiae genes

2013

Researchers have long been enthralled with the idea that gene duplication can generate novel functions, crediting this process with great evolutionary importance. Empirical data shows that whole-genome duplications (WGDs) are more likely to be retained than small-scale duplications (SSDs), though their relative contribution to the functional fate of duplicates remains unexplored. Using the map of genetic interactions and the re-sequencing of 27 Saccharomyces cerevisiae genomes evolving for 2,200 generations we show that SSD-duplicates lead to neo-functionalization while WGD-duplicates partition ancestral functions. This conclusion is supported by: (a) SSD-duplicates establish more genetic i…

0106 biological sciencesCancer ResearchGenome evolutionlcsh:QH426-470ArabidopsisSaccharomyces cerevisiaeBiology01 natural sciencesGenomeDivergenceEvolution Molecular03 medical and health sciencesMolecular evolutionPhylogeneticsGene DuplicationGene duplicationGeneticsMads-Box genesBiologyMolecular BiologyGenePhylogenyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologySmall-scale duplicationsGeneticsEvolutionary BiologyEvolutionary Theory0303 health sciencesAdaptive conflictHuman evolutionary geneticsNull mutationsSaccharomyces cerevisiae genomeProtein-Protein interactionslcsh:GeneticsEvolutionary biologyDiversificationEpistasisMolecular evolutionWhole-genome duplicationsGenome FungalYeast genomeInteractions revealResearch Article010606 plant biology & botany
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Selection for Robustness in Mutagenized RNA Viruses

2007

Mutational robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Whether robustness can be directly favored by natural selection remains controversial. Theory and in silico experiments predict that, at high mutation rates, slow-replicating genotypes can potentially outcompete faster counterparts if they benefit from a higher robustness. Here, we experimentally validate this hypothesis, dubbed the ‘‘survival of the flattest,’’ using two populations of the vesicular stomatitis RNA virus. Characterization of fitness distributions and genetic variability indicated that one population showed a higher replication rate, whereas the other was more robust to mut…

0106 biological sciencesCancer ResearchMutation ratelcsh:QH426-470In silicoMolecular Sequence DataPopulationBiologyVirus Replication010603 evolutionary biology01 natural sciencesVesicular stomatitis Indiana virusCell Line03 medical and health sciences0302 clinical medicineVirologyCricetinaeGeneticsAnimalsHumansSelection GeneticeducationMolecular BiologyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyGeneticsEvolutionary Biology0303 health scienceseducation.field_of_studyNatural selectionRobustness (evolution)Genetics and GenomicsRNA virusbiology.organism_classification3. Good healthlcsh:GeneticsViral replicationMutagenesisViral evolutionViruses030217 neurology & neurosurgeryResearch ArticleHeLa Cells
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De novo genome assembly of the land snail Candidula unifasciata (Mollusca: Gastropoda)

2021

Abstract Among all molluscs, land snails are a scientifically and economically interesting group comprising edible species, alien species and agricultural pests. Yet, despite their high diversity, the number of genome drafts publicly available is still scarce. Here, we present the draft genome assembly of the land snail Candidula unifasciata, a widely distributed species along central Europe, belonging to the Geomitridae family, a highly diversified taxon in the Western-Palearctic region. We performed whole genome sequencing, assembly and annotation of an adult specimen based on PacBio and Oxford Nanopore long read sequences as well as Illumina data. A genome draft of about 1.29 Gb was gene…

0106 biological sciencesCandidula unifasciataAcademicSubjects/SCI01140AcademicSubjects/SCI00010repeatsPopulationSnailsSequence assemblySnailQH426-470de novo assemblyAcademicSubjects/SCI01180010603 evolutionary biology01 natural sciencesGenome03 medical and health sciencesbiology.animalland snailslong readsGeneticsAnimalseducationMolecular BiologyGeneGenetics (clinical)030304 developmental biologyWhole genome sequencingGeomitridaemolluscs0303 health scienceseducation.field_of_studyGenomebiologyLand snailMolecular Sequence AnnotationGenomicsSequence Analysis DNAbiology.organism_classificationGenome ReportannotationEvolutionary biologyAcademicSubjects/SCI00960G3: Genes|Genomes|Genetics
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Effectiveness of sodium bicarbonate combined with hydrogen peroxide and CPP-ACPF in whitening and microhardness of enamel

2017

Background: This study investigated the effects of sodium bicarbonate (NaHCO3) combined with 1.5 hydrogen peroxide (H2O2) and casein phosphopeptide amorphous calcium phosphate fluoride (CPP-ACPF) on color and microhardness of enamel. Material and Methods: Seventy-five bovine incisors were immersed in a tea solution for 7.5 days. The specimens were randomly divided into five groups according to the whitening agent applied: 1) 94 NaHCO3, 2) a blend of 94 NaHCO3 and CPP-ACPF, 3) a blend of 94 NaHCO3 and 1.5 H2O2, 4) a blend of 94 NaHCO3, 1.5 H2O2 and CPP-ACPF, 5) control. The whitening procedure was performed for 10 times over 10 days. At each day, the buccal surfaces were covered with whiteni…

0106 biological sciencesDentistry01 natural sciences03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCaseinAmorphous calcium phosphateHydrogen peroxideGeneral DentistrySodium bicarbonateEnamel paintChemistrybusiness.industryResearch030206 dentistryBuccal administrationEsthetic Dentistry:CIENCIAS MÉDICAS [UNESCO]Stainingvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumbusinessFluoride010606 plant biology & botanyNuclear chemistry
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Predators' consumption of unpalatable prey does not vary as a function of bitter taste perception

2020

Many prey species contain defensive chemicals that are described as tasting bitter. Bitter taste perception is, therefore, assumed to be important when predators are learning about prey defenses. However, it is not known how individuals differ in their response to bitter taste, and how this influences their foraging decisions. We conducted taste perception assays in which wild-caught great tits (Parus major) were given water with increasing concentrations of bitter-tasting chloroquine diphosphate until they showed an aversive response to bitter taste. This response threshold was found to vary considerably among individuals, ranging from chloroquine concentrations of 0.01 mmol/L to 8 mmol/L.…

0106 biological sciencesEXPRESSIONDEFENSEmedia_common.quotation_subjectbitter tasteLibrary scienceConsumption (sociology)BiologySTRATEGIC DECISIONS010603 evolutionary biology01 natural sciencesBasic Behavioral and Social ScienceMONARCH BUTTERFLIES03 medical and health sciencesREPERTOIREBitter taste perceptionchemical defenseAvoidance learningExcellenceFOODBehavioral and Social ScienceaposematismDental/Oral and Craniofacial DiseaseEcology Evolution Behavior and SystematicsEDUCATED PREDATORS030304 developmental biologyIndependent researchmedia_commonNutrition0303 health sciencesBIRDSFOS: Clinical medicine3103 EcologyNeurosciencestoxinsBitter tastehumanitiesEVOLUTIONgreat titsRECEPTORS3109 ZoologyResearch councilavoidance learning1181 Ecology evolutionary biologybehavior and behavior mechanismsAnimal Science and Zoology31 Biological Sciences
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Novel simple templates for reproducible positioning of skin applicators in brachytherapy.

2016

Purpose : Esteya and Valencia surface applicators are designed to treat skin tumors using brachytherapy. In clinical practice, in order to avoid errors that may affect the treatment outcome, there are two issues that need to be carefully addressed. First, the selected applicator for the treatment should provide adequate margin for the target, and second, the applicator has to be precisely positioned before each treatment fraction. In this work, we describe the development and use of a new acrylic templates named Template La Fe-ITIC. They have been designed specifically to help the clinical user in the selection of the correct applicator, and to assist the medical staff in reproducing the po…

0106 biological sciencesEngineering drawingmedicine.medical_specialtyMedical staffelectronic brachytherapymedicine.medical_treatmentTreatment outcomeBrachytherapybrachytherapylcsh:Medicine01 natural sciences03 medical and health sciences0302 clinical medicineMargin (machine learning)medicineRadiology Nuclear Medicine and imagingMedical physicsReview Paperskin cancerbusiness.industrylcsh:RtemplateThin sheetClinical Practiceskin applicatorsTemplateOncology030220 oncology & carcinogenesisbusiness010606 plant biology & botanyJournal of contemporary brachytherapy
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