Search results for "clos"

Evolution of Cooperation Patterns in Psoriasis Research: Co-Authorship Network Analysis of Papers in Medline (1942–2013)

2015

BackgroundAlthough researchers have worked in collaboration since the origins of modern science and the publication of the first scientific journals in the eighteenth century, this phenomenon has acquired exceptional importance in the last several decades. Since the mid-twentieth century, new knowledge has been generated from within an ever-growing network of investigators, working cooperatively in research groups across countries and institutions. Cooperation is a crucial determinant of academic success.ObjectiveThe aim of the present paper is to analyze the evolution of scientific collaboration at the micro level, with regard to the scientific production generated on psoriasis research.Me…

Quantification of hydrolysis of toxic organophosphates and organophosphonates by diisopropyl fluorophosphatase from Loligo vulgaris by in situ Fourie…

2008

Abstract The enzyme diisopropyl fluorophosphatase (DFPase) from the squid Loligo vulgaris effectively catalyzes the hydrolysis of diisopropyl fluorophosphate (DFP) and a number of organophosphorus nerve agents, including sarin, soman, cyclosarin, and tabun. Up to now, the determination of kinetic data has been achieved by techniques such as pH-stat titration, ion-selective electrodes, and fluorogenic substrate analogs. We report a new assaying method using in situ Fourier transform infrared (FTIR) spectroscopy with attenuated total reflection (ATR) for the real-time determination of reaction rates. The method employs changes in the P–O–R stretching vibration of DFP and nerve agent substrate…

Extensive Assessment of Blood Glucose Monitoring During Postprandial Period and Its Impact on Closed-Loop Performance.

2017

[EN] Background: Closed-loop (CL) systems aims to outperform usual treatments in blood glucose control and continuous glucose monitors (CGM) are a key component in such systems. Meals represents one of the main disturbances in blood glucose control, and postprandial period (PP) is a challenging situation for both CL system and CGM accuracy. Methods: We performed an extensive analysis of sensor¿s performance by numerical accuracy and precision during PP, as well as its influence in blood glucose control under CL therapy. Results: During PP the mean absolute relative difference (MARD) for both sensors presented lower accuracy in the hypoglycemic range (19.4 ± 12.8%) than in other ranges (12.2…

Timing of deformational events in the Río San Juan complex: implications for the tectonic controls on the exhumation of high-P rocks in the northern …

2013

An integrated structural, petrological and geochronological study was undertaken to constrain the tectonic history and controls on the exhumation of the high-P rocks of the Río San Juan complex in the northern Caribbean subduction–accretionary wedge. In the main structural units of the complex, microtextural analyses were performed to identify the fabrics formed at peak ofmetamorphismin eclogite-facies conditions and during the main retrogressive event toward the low-P amphibolite or blueschist/greenschist-facies conditions. U–Pb SHRIMP dating on zircon rims (71.3 ± 0.7 Ma) coupled with 40Ar–39Ar analyses on phengite (~70– 69 Ma) in felsic sills placed temporal constraints on the exhumation…

3D boundary element analysis of delamination crack using the Modified Crack Closure Integral

2012

The COGNITION Study Rationale and Design: Influence of Closed Loop Stimulation on Cognitive Performance in Pacemaker Patients

2008

Background: Several studies showed the beneficial effect of pacemaker implantation on cognitive performance in patients with bradycardia. But it has never been investigated if patients with chronotropic incompetence may improve their cognitive performance if treated by a rate-adaptive system reacting to mental stress in comparison to the most frequently used accelerometer-driven pacing. Methods: The randomized, single-blind, multicenter COGNITION study evaluates if closed loop stimulation (CLS) offers incremental benefit in the speed of cognitive performance and the overall well-being of elderly patients with bradycardia compared with accelerometer-based pacing. Four hundred chronotropicall…

Utilization of pedicled buccal fat pads for coverage of the lateral relaxing wound: A review of literature and a case series of 15 patients

2018

Background The buccal fat pad (BFP) is an encapsulated mass originated from a specific fat tissue in various volume throughout the life of each person and BFP has been used in various surgeries as a source of useful graft material due to its easy accessibility and rich vascularization. Case Report This report describes fifteen patients who were treated with buccal fat pads (BFP) as a pedicled graft for lateral relaxing wound closure in primary cleft palate surgery. A review of relevant literature is also presented. Results All patients had a mean follow-up of 3.7 weeks with a minimum follow-up time of three weeks and a maximum follow-up of four weeks. All patients who had an uneventful imme…

The influence of reverse flow on the dynamics of closed-loop supply chains

2014

The purpose of this paper is to study the impact of reverse logistics’ factors on the order and inventory variance amplification in a closed-loop supply chain. We adopt a difference equation math approach for analysing a closed-loop supply chain. Results show how the return flow positively affects both the inventory variance and the bullwhip effect independently of the number of echelons. On the contrary, an increasing remanufacturing lead-time negatively affects both the two metrics studied independently of the above mentioned settings. However, when the number of echelons increases, the benefit provided by the return flow tends to decrease.

The validity of the “liminf” formula and a characterization of Asplund spaces

2014

Abstract We show that for a given bornology β on a Banach space X the following “ lim inf ” formula lim inf x ′ ⟶ C x T β ( C ; x ′ ) ⊂ T c ( C ; x ) holds true for every closed set C ⊂ X and any x ∈ C , provided that the space X × X is ∂ β -trusted. Here T β ( C ; x ) and T c ( C ; x ) denote the β-tangent cone and the Clarke tangent cone to C at x. The trustworthiness includes spaces with an equivalent β-differentiable norm or more generally with a Lipschitz β-differentiable bump function. As a consequence, we show that for the Frechet bornology, this “ lim inf ” formula characterizes in fact the Asplund property of X. We use our results to obtain new characterizations of T β -pseudoconve…

Structural and functional changes in the gut microbiota associated to Clostridium difficile infection

2014

Antibiotic therapy is a causative agent of severe disturbances in microbial communities. In healthy individuals, the gut microbiota prevents infection by harmful microorganisms through direct inhibition (releasing antimicrobial compounds), competition, or stimulation of the host’s immune defenses. However, widespread antibiotic use has resulted in short- and long-term shifts in the gut microbiota structure, leading to a loss in colonization resistance in some cases. Consequently, some patients develop Clostridium difficile infection (CDI) after taking an antibiotic (AB) and, at present, this opportunistic pathogen is one of the main causes of antibiotic-associated diarrhea in hospitalized p…