Search results for "coding"
showing 10 items of 920 documents
Context-dependent minimisation of prediction errors involves temporal-frontal activation
2020
According to the predictive coding model of perception, the brain constantly generates predictions of the upcoming sensory inputs. Perception is realised through a hierarchical generative model which aims at minimising the discrepancy between predictions and the incoming sensory inputs (i.e., prediction errors). Notably, prediction errors are weighted depending on precision of prior information. However, it remains unclear whether and how the brain monitors prior precision when minimising prediction errors in different contexts. The current study used magnetoencephalography (MEG) to address this question. We presented participants with repetition of two non-predicted probes embedded in cont…
Diagonal space time hadamard codes with erasure decoding algorithm
2005
A major challenge in the area of space time (ST) codes is to find codes suitable for efficient decoding, thus overcoming the problem of many existing ST code designs which require maximum-likelihood (ML) decoding. A solution could be to apply single-input single-output (SISO) channel codes and theory over temporal channel fading to the multi-input single-output (MISO) code construction and classical suboptimum decoding methods. For these purposes, an ST code construction which allows the use of efficient decoding algorithms is described. We propose a concatenated code, where the inner code is the diagonal ST Hadamard (D-STH) code with Paley constructions and the outer code is an algebraic b…
Transducers for the bidirectional decoding of prefix codes
2010
AbstractWe construct a transducer for the bidirectional decoding of words encoded by the method introduced by Girod (1999) in [5] and we prove that it is bideterministic and that it can be used both for the left-to-right and the right-to-left decoding.We also give a similar construction for a transducer that decodes in both directions words encoded by a generalization of Girod’s encoding method. We prove that it has the same properties as those of the previous transducer. In addition we show that it has a single initial/final state and that it is minimal.
Coding Sequences with Constraints
1990
In this paper we consider the following problem: given all bi-infinite sequences of symbols satisfying certain constraints, search for a set X of words such that i): any concatenation of elements of X satisfies these constraints and ii): any sequence verifying the constraints can be “parsed” in elements of X.
A Generalization of Girod's Bidirectional Decoding Method to Codes with a Finite Deciphering Delay
2012
Girod’s encoding method has been introduced in order to efficiently decode from both directions messages encoded by using finite prefix codes. In the present paper, we generalize this method to finite codes with a finite deciphering delay. In particular, we show that our decoding algorithm can be realized by a deterministic finite transducer. We also investigate some properties of the underlying unlabeled graph.
Interaction of 68–kDa TAR RNA-binding protein and other cellular proteins with rpion protein-RNA stem-loop
1995
The RNA stem-loop structure of the trans-activating region TAR sequence of human immunodeficiency virus-1 mRNA is the binding site for a number of host cell proteins. A virtually identical set of proteins from HeLa nuclear extracts was found to bind to the predicted RNA hairpin element of prion protein (PrP) mRNA, as demonstrated in UV cross-linking/RNase protection and Northwestern assays. We show that the cellular TAR loop-binding protein, p68, is among those proteins which associate with PrP RNA. Competition experiments with various TAR RNA mutants revealed that binding of partially purified p68 to PrP RNA stem-loop occurs sequence-specifically. The 100-kDa 2-5A synthetase which is invol…
Germline correction of an epimutation related to Silver-Russell syndrome.
2015
Like genetic mutations, DNA methylation anomalies or epimutations can disrupt gene expression and lead to human diseases. However, unlike genetic mutations, epimutations can in theory be reverted through developmental epigenetic reprograming, which should limit their transmission across generations. Following the request for a parental project of a patient diagnosed with Silver-Russell syndrome (SRS), and the availability of both somatic and spermatozoa DNA from the proband and his father, we had the exceptional opportunity to evaluate the question of inheritance of an epimutation. We provide here for the first time evidence for efficient reversion of a constitutive epimutation in the sperm…
Genome-wide variant calling in reanalysis of exome sequencing data uncovered a pathogenic TUBB3 variant.
2021
Almost half of all individuals affected by intellectual disability (ID) remain undiagnosed. In the Solve-RD project, exome sequencing (ES) datasets from unresolved individuals with (syndromic) ID (n = 1,472 probands) are systematically reanalyzed, starting from raw sequencing files, followed by genome-wide variant calling and new data interpretation. This strategy led to the identification of a disease-causing de novo missense variant in TUBB3 in a girl with severe developmental delay, secondary microcephaly, brain imaging abnormalities, high hypermetropia, strabismus and short stature. Interestingly, the TUBB3 variant could only be identified through reanalysis of ES data using a genome-wi…
Catalyzing transcriptomics research in cardiovascular disease: The CardioRNA COST action CA17129
2019
WOS: 000474931400001
Might exogenous circular RNAs act as protein-coding transcripts in plants?
2021
Circular RNAs (circRNAs) are regulatory molecules involved in the modulation of gene expression. Although originally assumed as non-coding RNAs, recent studies have evidenced that animal circRNAs can act as translatable transcripts. The study of plant-circRNAs is incipient, and no autonomous coding plant-circRNA has been described yet. Viroids are the smallest plant-pathogenic circRNAs known to date. Since their discovery 50 years ago, viroids have been considered valuable systems for the study of the structure-function relationships in RNA, essentially because they have not been shown to have coding capacity. We used two pathogenic circRNAs (Hop stunt viroid and Eggplant latent viroid) as …