Search results for "cognició"
showing 10 items of 102 documents
Lifespan Changes of the human brain in Alzheimer's disease
2018
[EN] Brain imaging studies have shown that slow and progressive cerebral atrophy characterized the development of Alzheimer's Disease (AD). Despite a large number of studies dedicated to AD, key questions about the lifespan evolution of AD biomarkers remain open. When does the AD model diverge from the normal aging model? What is the lifespan trajectory of imaging biomarkers for AD? How do the trajectories of biomarkers in AD differ from normal aging? To answer these questions, we proposed an innovative way by inferring brain structure model across the entire lifespan using a massive number of MRI (N = 4329). We compared the normal model based on 2944 control subjects with the pathological …
Influencia del aceite de coco en enfermos de alzhéimer a nivel cognitivo.
2017
Resumen Introducción: la enfermedad de Alzheimer es a día de hoy la demencia neurodegenerativa con mayor prevalencia en el primer mundo. Este hecho, unido a la falta de tratamiento farmacológico que cure la enfermedad, hace que se estudien nuevas estrategias terapéuticas no farmacológicas como es la administración de nutrientes. En este sentido, destaca la posible influencia del aceite de coco como fuente energética alternativa, capaz de frenar la muerte neuronal que se produce de modo progresivo en esta enfermedad. Objetivos: valorar el impacto del aceite de coco a nivel cognitivo en pacientes de alzhéimer, y concretamente en las áreas de orientación, lenguaje-construcción, fijación, cálcu…
Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy
2019
Radiotherapy is a highly effective tool for the treatment of brain cancer. However, radiation also causes detrimental effects in the healthy tissue, leading to neurocognitive sequelae that compromise the quality of life of brain cancer patients. Despite the recognition of this serious complication, no satisfactory solutions exist at present. Here we investigated the effects of intranasal administration of human mesenchymal stem cells (hMSCs) as a neuroprotective strategy for cranial radiation in mice. Our results demonstrated that intranasally delivered hMSCs promote radiation-induced brain injury repair, improving neurological function. This intervention confers protection against inflamma…
El papel del mindfulness y el descentramiento en la sintomatología depresiva y ansiosa
2016
ResumenLos síntomas depresivos y ansiosos tienen un claro impacto en el funcionamiento de las personas. Su aparición parece tener relación con la presencia de déficits en las capacidades metacognitivas. El entrenamiento en atención plena aumenta el insight metacognitivo a través de la capacidad de descentramiento. Por ello el objetivo de este estudio ha sido evaluar la relación entre la atención plena y el descentramiento con la sintomatología ansiosa y depresiva respectivamente. La muestra de este estudio está compuesta por 465 participantes y el contacto con ella se estableció a través de universidades y redes sociales. Los resultados revelaron que tanto la atención plena como la capacida…
Diseño y validación de un instrumento para evaluar la competencia "Aprender a aprender" en profesionales de la educación
2015
Desde la década de los años 90, la educación gira hacia el modelo orientado al desarrollo de competencias. Diversas aportaciones de gran calado (Delors, 1996; Eurydice, 2002; OCDE , 2005; Proyecto Tuning, 2007) se han ido constituyendo en referencias conceptuales para el diseño, desarrollo y organización de la Enseñanza y de la Educación. En este marco, el Espacio Europeo de Educación Superior ha incorporado esta orientación pedagógica, señalando la necesidad de abordar el desarrollo en las titulaciones universitarias de competencias generales y específicas. Se destaca como denominador común el hecho de que todas ellas implican preparar a la persona para aprender a aprender. El hecho de rec…
Effects of an incremental maximal endurance exercise stress-induced cortisol on cognitive performance
2019
Exercise; Cognitive functions; Cortisol Ejercicio físico; Funciones cognitivas; Cortisol Exercici físic; Funcions cognitives; Cortisol Objectives: It can be hypothesized that cognitive performance decreases after fatigue protocol when it coincides with the maximum peak of cortisol. The first aim of this study was to elucidate the effects of a single bout of high intensity exercise on behavioural (i.e., attention and memory) and physiological (i.e., salivary cortisol) responses. The second objective was to evaluate the effect of the performance of the cognitive tasks on cortisol levels. Methods: Thirty-four physically active men (at least 5 days/week of physical activity practice) 38.11 (1.5…
Effects of functional remediation on neurocognitively impaired bipolar patients: enhancement of verbal memory
2016
BackgroundFunctional remediation is a novel intervention with demonstrated efficacy at improving functional outcome in euthymic bipolar patients. However, in a previous trial no significant changes in neurocognitive measures were detected. The objective of the present analysis was to test the efficacy of this therapy in the enhancement of neuropsychological functions in a subgroup of neurocognitively impaired bipolar patients.MethodA total of 188 out of 239 DSM-IV euthymic bipolar patients performing below two standard deviations from the mean of normative data in any neurocognitive test were included in this subanalysis. Repeated-measures analyses of variance were conducted to assess the i…
Clinical usefulness of the screen for cognitive impairment in psychiatry (SCIP-S) scale in patients with type I bipolar disorder
2009
Abstract Background The relevance of persistent cognitive deficits to the pathogenesis and prognosis of bipolar disorders (BD) is understudied, and its translation into clinical practice has been limited by the absence of brief methods assessing cognitive status in Psychiatry. This investigation assessed the psychometric properties of the Spanish version of the Screen for Cognitive Impairment in Psychiatry (SCIP-S) for the detection of cognitive impairment in BD. Methods After short training, psychiatrists at 40 outpatient clinics administered the SCIP three times over two weeks to a total of 76 consecutive type I BD admissions. Experienced psychologists also administered a comprehensive ba…
The switch from conventional to atypical antipsychotic treatment should not be based exclusively on the presence of cognitive deficits. A pilot study…
2010
Abstract Background Atypical antipsychotics provide better control of the negative and affective symptoms of schizophrenia when compared with conventional neuroleptics; nevertheless, their heightened ability to improve cognitive dysfunction remains a matter of debate. This study aimed to examine the changes in cognition associated with long-term antipsychotic treatment and to evaluate the effect of the type of antipsychotic (conventional versus novel antipsychotic drugs) on cognitive performance over time. Methods In this naturalistic study, we used a comprehensive neuropsychological battery of tests to assess a sample of schizophrenia patients taking either conventional (n = 13) or novel a…
Guided collaboration and computers: Some of its effects on learning outcome
2004
The purpose of the study was to investigate the effects of different treatments on learning outcome, into a collaborative learning context. It was used a factorial design, consisting of two factors, each one with two categories. The first factor was to give students specific roles to play to guide the kinds of interactions and activities that students engage in, versus to allow students to make their own decisions about when and how to use the teacher instructions. The second one was to develop a simple hypertext, versus to write an extended essay. It was found that the factor 'specific roles' favored the learning outcome, whereas the factor 'hypertext development' was not statistically sig…