Search results for "complex"
showing 10 items of 5889 documents
14th International HLA and Immunogenetics Workshop: Report on the Prospective Chronic Rejection Project
2007
An international collaborative study of 45 transplant centers was undertaken at the 14th International HLA (human leukocyte antigen) and Immunogenetics Workshop to see if HLA antibodies detected posttransplant are predictive of chronic graft failure. With the newly developed assay, MICA (major histocompatibility complex class I-related chain A) antibodies were also measured and their effect analyzed. Total of 5219 sera from patients who were more than 6 months posttransplant with functioning graft were tested for HLA antibodies by enzyme-linked immunosorbent assay, flow cytometry, or Luminex. HLA antibodies were found in 27.2% of kidney patients, 23.6% in the liver, 52.7% in the heart, and …
Induction and tolerization of anti-male CD8+ cytotoxic T lymphocytes by in vivo immunization with an H-Y-derived peptide
1999
Abstract We have analyzed the immune response induced by a 9mer synthetic peptide derived from the male histocompatibility antigen H-Y and containing D b -binding motifs in C57BL/6 mice. In this study we report that a single, subcutaneous injection of the peptide emulsified in IFA gave rise to the development of male-specific CD8 + T cells which displayed H-Y-specific proliferative response in vitro and showed a Tc1-type pattern of cytokine production (i.e. they secreted IFN-γ and IL-2, but not IL-4 and IL-10). Development of a strong cytotoxic activity required in vitro stimulation with specific peptide and IL-2: under these culture conditions, we were able to generate potent CD8 + CTLs th…
Response of soil bacteria to Hg (II) in relation to soil characteristics and cell location
2006
The response of indigenous bacterial communities to the addition of inorganic mercury (50 μM of Hg(II)) was compared over a 30 day period in four soils of contrasting properties. Hg(II) impact was estimated by following population dynamics of viable heterotrophic bacteria (VH) and mercury resistant bacteria (HgR) by indirect enumeration in unfractionated soil and in the inner and outer parts of soil aggregates obtained by successive washings. Numbers of VH bacteria in unfractionated soils were not affected by mercury in any of the studied soils, whereas an increase in resistant bacteria was observed in all of them. The lag phase before the increase of HgR bacteria and the magnitude of the e…
Approximate energy functionals for one-body reduced density matrix functional theory from many-body perturbation theory
2018
We develop a systematic approach to construct energy functionals of the one-particle reduced density matrix (1RDM) for equilibrium systems at finite temperature. The starting point of our formulation is the grand potential $\Omega [\mathbf{G}]$ regarded as variational functional of the Green's function $G$ based on diagrammatic many-body perturbation theory and for which we consider either the Klein or Luttinger-Ward form. By restricting the input Green's function to be one-to-one related to a set on one-particle reduced density matrices (1RDM) this functional becomes a functional of the 1RDM. To establish the one-to-one mapping we use that, at any finite temperature and for a given 1RDM $\…
Interplay among Gcn5, Sch9 and mitochondria during chronological aging of wine yeast is dependent on growth conditions.
2015
Saccharomyces cerevisiae chronological life span (CLS) is determined by a wide variety of environmental and genetic factors. Nutrient limitation without malnutrition, i.e. dietary restriction, expands CLS through the control of nutrient signaling pathways, of which TOR/Sch9 has proven to be the most relevant, particularly under nitrogen deprivation. The use of prototrophic wine yeast allows a better understanding of the role of nitrogen in longevity in natural and more demanding environments, such as grape juice fermentation. We previously showed that acetyltransferase Gcn5, a member of the SAGA complex, has opposite effects on CLS under laboratory and winemaking conditions, and is detrimen…
Filtering Real World Networks: A Correlation Analysis of Statistical Backbone Techniques
2023
Networks are an invaluable tool for representing and understanding complex systems. They offer a wide range of applications, including identifying crucial nodes, uncovering communities, and exploring network formation. However, when dealing with large networks, the computational challenge can be overwhelming. Fortunately, researchers have developed several techniques to address this issue by reducing network size while preserving its fundamental properties [1-9]. To achieve this goal, two main approaches have emerged: structural and statistical methods. Structural methods aim to keep a set of topological features of the network while reducing its size. In contrast, statistical methods elimi…
NetBone: A Python Package for Extracting Backbones of Weighted Networks
2023
NetBone is a new open-source Python package designed to simplify analyzing complex networks. With a wide range of techniques available, Net-Bone allows researchers to extract the backbone of a network while preserving its essential structure. The package includes nine structural methods and five statistical techniques, offering users a comprehensive solution to network analysis. It is user-friendly and straightforward to use, with easy installation. The package accepts different types of inputs, including data frames or Networkx graphs, and provides evaluation measures for comparative purposes. Additionally, NetBone offers an option to generate plots. Its versatility makes it a valuable too…
Two Reflected Gray Code-Based Orders on Some Restricted Growth Sequences
2014
We consider two order relations: that induced by the m-ary reflected Gray code and a suffix partitioned variation of it. We show that both of them when applied to some sets of restricted growth sequences still yield Gray codes. These sets of sequences are: subexcedant and ascent sequences, restricted growth functions and staircase words. In particular, we give the first suffix partitioned Gray codes for restricted growth f unctions and ascent sequences; these latter sequences code various combinatorial classes as interval orders, upper triangular matrices without zero rows and zero columns whose non-negative integer entries sum up to n, and certain pattern-avoiding permutations. For each Gr…
Parallel Algorithms for Listing Well-Formed Parentheses Strings
1998
We present two cost-optimal parallel algorithms generating the set of all well-formed parentheses strings of length 2n with constant delay for each generated string. In our first algorithm we generate in lexicographic order well-formed parentheses strings represented by bitstrings, and in the second one we use the representation by weight sequences. In both cases the computational model is based on an architecture CREW PRAM, where each processor performs the same algorithm simultaneously on a different set of data. Different processors can access the shared memory at the same time to read different data in the same or different memory locations, but no two processors are allowed to write i…
Ultra-Low Catalyst Loading as a Concept in Economical and Sustainable Modern Chemistry: The Contribution of Ferrocenylpolyphosphane Ligands
2007
The challenge of sustainability in modern chemistry will be met with new technologies and processes provided significant progress is made in several key research areas, such as the expansion of chemistry from renewable feedstock, the design of environmentally benign chemicals and solvents, the minimization of depletive resources, and the development of high-performance catalysis. In this prospect, ligand chemistry is a pivotal science that links modern-organic,-inorganic, -organometallic, and -coordination chemistry through a vast number of valuable applications, precisely associated to catalysis. We review in this article our recent work on catalysis promoted by original ferrocenyl tetra-,…