Search results for "complication"

showing 10 items of 2051 documents

Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis

2010

The ADA and the EASD recently published a consensus statement for the medical management of hyperglycaemia in patients with type 2 diabetes. The authors advocate initial treatment with metformin monotherapy and lifestyle modification, followed by addition of basal insulin or a sulfonylurea if glycaemic goals are not met (tier 1 recommendations). All other glucose-lowering therapies are relegated to a secondary (tier 2) status and only recommended for selected clinical settings. In our view, this algorithm does not offer physicians and patients the appropriate selection of options to individualise and optimise care with a view to sustained control of blood glucose and reduction both of diabe…

cardiovascular riskGlucose-lowering therapyEndocrinology Diabetes and MetabolismeducationSocieties Medical/standardsMEDLINE10265 Clinic for Endocrinology and DiabetologyHypoglycemic Agents/therapeutic use610 Medicine & healthType 2 diabetesHyperglycemia/drug therapyLifestyle modificationRisk FactorsDiabetes mellitusTier 2 networkADA Consensus StatementmedicineInternal MedicineInitial treatmentHyperglycaemiaHumansIn patientFor Debatealgorithmbusiness.industrynutritional and metabolic diseasesType 2 diabetesmedicine.diseaseCardiovascular riskUnited StatesMetforminEASD consensus statementglucose-lowering therapyAlgorithmEurope2712 Endocrinology Diabetes and Metabolism2724 Internal Medicine*AlgorithmsDiabetes Mellitus Type 2/complications/*drug therapytype 2 diabetesbusinessAlgorithmCardiovascular Diseases/prevention & controlhyperglycaemiamedicine.drug
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Choroidal thickness is associated with renal hemodynamics in essential hypertension

2020

The choroid is the most vascularized structure of the eye and plays a central role in the development of the retinal vascular changes that occur in arterial hypertension. Changes of choroidal thickness (ChT) assessed by optical coherence tomography (OCT) technology could reflect the vascular complications of hypertension. Also, intrarenal hemodynamic damage, associated with endothelial dysfunction, demonstrated to be a good indicator of systemic morphofunctional arterial impairment. The aim of this study is to assess the relationship between ChT and renal hemodynamics in subjects with essential hypertension. Routine laboratory tests, clinical history, and physical examination, including blo…

choroidal thicknessrenal hemodynamicsmedicine.medical_specialtyhypertensionEndocrinology Diabetes and MetabolismThe Kidneyrenal hemodynamicHemodynamicsPhysical examination030204 cardiovascular system & hematologyKidneyEssential hypertension03 medical and health sciences0302 clinical medicinechoroidal thickness; chronic kidney disease; hypertension; renal hemodynamics; renal resistive indexInternal medicineInternal MedicinemedicineHumans030212 general & internal medicineEndothelial dysfunctionchoroidal thicknemedicine.diagnostic_testChoroidbusiness.industryrenal resistive indexConfoundingHemodynamicsmedicine.diseaseBlood pressuremedicine.anatomical_structureCardiologyVascular ResistanceChoroidEssential HypertensionComplications of hypertensionCardiology and Cardiovascular Medicinebusinesschronic kidney diseaseThe Journal of Clinical Hypertension
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Influence of patient-related factors on intraoperative blood loss during double opposing Z-plasty Furlow palatoplasty and buccal fat pad coverage:A p…

2022

Background: Surgical procedures including palatoplasty have a risk for complications. The aim of this study was to investigate the intraoperative and early postoperative blood loss using the buccal fat pad (BFP) during cleft lip and/or cleft palate (CL/P) surgery. Material and Methods: This prospective study included a total of 109 patients with cleft palate (CP) during a three-month period of treatment at Hasanuddin University Dental Hospital (permanent center) and charity trips in rural parts of Eastern Indonesia. All patients were treated with DOZ Furlow technique combined with BFP graft. Before and after surgery, the total amount of intraoperative blood loss was calculated by measuring …

cleft palateBuccal fat padSDG 3 - Good Health and Well-being/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingcomplicationcleft lippalatoplastyGeneral DentistryUNESCO:CIENCIAS MÉDICAS
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The Association between Cognitive Impairment and Diabetic Foot Care: Role of Neuropathy and Glycated Hemoglobin

2020

Diabetes mellitus is associated with impairment in cognitive functions which can complicate adherence to self-care behaviors. We evaluated the incidence of cognitive impairment in patients with diabetes mellitus to determine the strength of the association between diabetic foot (a complication that occurs in about 10% of diabetic patients), adherence to the clinician&rsquo

cognitionmedicine.medical_specialtyHbA1cdiabetic foot complicationPhysiologyTrail Making Test030209 endocrinology & metabolism03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDiabetes mellitusInternal medicineMedicineQP1-981030212 general & internal medicineProspective cohort studyGlycemicskin diseaseDiabetisdiabetesbusiness.industryCognitionGeneral Medicinemedicine.diseaseDiabetic footExtremitatschemistryskin diseasesexecutive functiondiabeteneuropathyGlycated hemoglobinbusinessFoot (unit)Pathophysiology
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Femoral Versus Radial Artery Access for CTO PCIs: Is This the Final Round?

2022

Historically, cardiac catheterization has been performed via transfemoral access (TFA). Although TFA remains necessary in multiple diagnostic and interventional settings, this technique has been associated with vascular access site complication rates ranging from 2% to 6%, prolonged hospital stay, and more deaths compared with radial artery access. Furthermore, safe utilization of the femoral artery can be compromised by abdominal obesity, atherosclerosis at the puncture site, and antithrombotic therapy, all which increase the bleeding risk.1 In the last decade, transradial artery access (TRA) emerged as the recommended approach for percutaneous coronary interventions (PCI), particularly in…

complex PCICTO PCIvascular complications.transradial CTO PCI
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Fabry Disease With Concomitant Lewy Body Disease

2019

AbstractAlthough Gaucher disease can be accompanied by Lewy pathology (LP) and extrapyramidal symptoms, it is unknown if LP exists in Fabry disease (FD), another progressive multisystem lysosomal storage disorder. We aimed to elucidate the distribution patterns of FD-related inclusions and LP in the brain of a 58-year-old cognitively unimpaired male FD patient suffering from predominant hypokinesia. Immunohistochemistry (CD77, α-synuclein, collagen IV) and neuropathological staging were performed on 100-µm sections. Tissue from the enteric or peripheral nervous system was unavailable. As controls, a second cognitively unimpaired 50-year-old male FD patient without LP or motor symptoms and 3…

complications [Lewy Body Disease]MalePathologyAutopsyDisease0302 clinical medicineHypokinesiapathology [Brain]Lysosomal storage diseasespathology [Neurons]metabolism [alpha-Synuclein]metabolism [Fabry Disease]pathology [Astrocytes]Neuronsα-Synuclein0303 health sciencesParkinsonismTrihexosylceramidesBrainGeneral MedicineMiddle AgedParkinson diseasecomplications [Fabry Disease]Neurologymetabolism [Neurons]alpha-Synucleinmedicine.symptomLewy Body Diseasemedicine.medical_specialtymetabolism [Lewy Body Disease]Context (language use)Substantia nigrametabolism [Trihexosylceramides]Pathology and Forensic Medicineblood supply [Brain]03 medical and health sciencesCellular and Molecular Neuroscienceα-Galactosidase AmedicineHumansddc:610030304 developmental biologypathology [Lewy Bodies]Fabry diseasebusiness.industryPars compactapathology [Lewy Body Disease]Lewy bodies/neuritesOriginal Articlesmetabolism [Lewy Bodies]medicine.diseaseFabry diseasemetabolism [Brain]AstrocytesLewy BodiesNeurology (clinical)CD77pathology [Fabry Disease]business030217 neurology & neurosurgeryJournal of Neuropathology and Experimental Neurology
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Operācijas laika ietekme uz apendektomijas rezultātu

2018

Kopsavilkums Nosaukums: Operācijas laika izvēles ietekme uz apendektomijas rezultātu Fons: Apendektomija ir viena no pasaulē visbiežāk veiktajām akūtajām ķirurģiskajām manipulācijām. Vēsturiski to veic nekavējoties un neatkarīgi no diennakts laika. Tomēr ir svarīgi jautāt, vai laika izvēle ietekmē klīnisko rezultātu. Mērķis: Pētījuma mērķis ir izvērtēt, vai apendektomiju ir iespējams aizkavēt vai arī tiešas ķirurģiskas iejaukšanās gadījumā rezultāts būs labāks. Materiāli un metodes: Šis ir retrospektīvs pētījums ar nejauši atlasītiem pacientiem ar apendektomiju, kas veikta Rīgas Austrumu klīniskajā universitātes slimnīcā 2015. un 2016. gadā. Vērtējuma parametri; vecums, dzimums, ķirurģiskai…

complications of appendicitisTiming of operationDuration until operationpostoperative complicationsappendectomyMedicīna
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Influence of Biologically Oriented Preparation Technique on Peri-Implant Tissues; Prospective Randomized Clinical Trial with Three-Year Follow-Up. Pa…

2019

Purpose: The objective of this prospective randomized clinical trial (RCT) was to analyze and compare the clinical behavior of three types of prosthesis supported by single implants in the posterior region after three years of functional loading. Materials and methods: Seventy-five implants were divided into three groups according to the type of prosthetic restoration: screw-retained crown (group GS); cemented crown without finishing line (biologically oriented preparation technique) (group GBOPT); and conventional cemented crown with finishing line (group GCC). After three years in function, clinical parameters (presence of keratinized mucosa, probing depths, bleeding on probing, and radio…

complicationsmedicine.medical_treatmentRadiographyBleeding on probingPeriDentistryProsthesisCrown (dentistry)Articlelaw.invention03 medical and health sciencesimplant-supported prosthesis0302 clinical medicineRandomized controlled triallaw0502 economics and businessmedicinebusiness.industry05 social sciencesSoft tissue030206 dentistryGeneral MedicineBOPTscrew-retainedbone loss and clinical parameterscemented050211 marketingImplantmedicine.symptombusinesssoft tissuesJournal of Clinical Medicine
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Does Hysteroscopic Dissection of Partial Uterine Septum Represent a Risk Factor for Placental Abnormalities in Subsequent Pregnancy Compared with Con…

2022

Background: Hysteroscopic septum dissection (HSD) is thought to improve fertility and pregnancy outcomes. However, the available literature suggests that uterine surgery can cause placental abnormalities in subsequent pregnancies. Methods: A case–control study was performed at the University Medical Center of Ljubljana, Department of Human Reproduction, from 1 January 2016 to 31 December 2018. The primary outcome was the association between HSD and the occurrence of placental abnormalities. We included women who underwent HSD due to infertility. Age-matched women who underwent hysteroscopic surgery for other issues were considered as controls. In addition, we divided the groups according to…

congenital uterine anomalies; uterine septum dissection; placental abnormalities; neonatal outcome; IVF/ICSI; hysteroscopy; complicationsComplicationsUterine septum dissectionIVF/ICSIGeneral MedicineCongenital uterine anomaliesHysteroscopyNeonatal outcomeSettore MED/40 - Ginecologia E OstetriciaPlacental abnormalities
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Von Willebrand-Syndrom - Blutungsrisiko bei HNO-Eingriffen im Kindesalter

1994

Von Willebrand's disease (vWD) is the most common inherited bleeding disorder. Typical clinical features such as bleeding after surgery or trauma might suggest the disease. We present a series of 24 patients with vWD treated between 1989 and 1992. Diagnosis was confirmed by a reduction in plasma factor VIII antigen concentration, reduction of ristocetin cofactor activity and reduced factor VIII activity. Seventeen of the patients underwent surgery (7 adenoidectomies, 8 tonsillectomies, 2 paranasal sinus operations) and received preoperative stimulation of von Willebrand factor (vWF) using DDAVP. This resulted in a rapid increase in plasma vWF concentration from an average of 56% before stim…

congenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtybiologymedicine.diagnostic_testbusiness.industryPlasma factorStimulationGastroenterologySurgeryOtorhinolaryngologyVon Willebrand factorVon willebrandhemic and lymphatic diseasesInternal medicinebiology.proteinMedicineRisk factorbusinessReduced factor VIII activityComplicationcirculatory and respiratory physiologyPartial thromboplastin timeLaryngo-Rhino-Otologie
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