Search results for "computing"
showing 10 items of 25279 documents
Induced Night-Vision by Singlet-Oxygen-Mediated Activation of Rhodopsin
2019
In humans, vision is limited to a small fraction of the whole electromagnetic spectrum. One possible strategy for enhancing vision in deep-red or poor-light conditions consists of recruiting chlorophyll derivatives in the rod photoreceptor cells of the eye, as suggested in the case of some deep-sea fish. Here, we employ all-atom molecular simulations and high-level quantum chemistry calculations to rationalize how chlorin e6 (Ce6), widely used in photodynamic therapy although accompanied by enhanced visual sensitivity, mediates vision in the dark, shining light on a fascinating but largely unknown molecular mechanism. First, we identify persistent interaction sites between Ce6 and the extra…
<title>Modified crossed-cylinder aberroscope</title>
2001
We report a technique to estimate eye aberrations, based mainly on the subjective crossed-cylinder method. In order to obtain accurate coordinates of cross sections of the aberration distorted grid image on the retinal plane, needed in subjective methods, fusion of two images is used. The image seen by the eye under investigation is fused by the patient with a similar grid generated and reshaped in the appropriate way on the computer screen. The computer simulated image is viewed either by the second eye (in order to avoid eye rivalry and suppression processes, that are typical for such conditions, stimuli for both eyes are discontinuous and are displayed sequentially with a frequency of 50…
The mechanisms of the action of omega-3s in the retina
2013
Age-related Macular Degeneration (AMD) is the leading cause of visual loss in Western countries after the age of 50y. Based on large-scale epidemiologic studies, it appears now as evident that omega-3 polyunsaturated fatty acids (PUFAs) provide benefits in preventing both, early and late stages of AMD. The aim of this paper is to summarize the knowledge about the biological mechanisms by which omega-3 PUFAs may be protective for the retina. The content of this presentation will range from biochemical data about the occurrence of omega-3 PUFAs in retinal cell membranes to results from cellular and animal studies showing that omega-3 PUFAs can influence processes involved in signal transducti…
In vitro evolution of an atrazine-degrading population under cyanuric acid selection pressure: Evidence for the selective loss of a 47kb region on th…
2011
International audience; The adaptation of microorganisms to pesticide biodegradation relies on the recruitment of catabolic genes by horizontal gene transfer and homologous recombination mediated by insertion sequences (IS). This environment-friendly function is maintained in the degrading population but it has a cost which could diminish its fitness. The loss of genes in the course of evolution being a major mechanism of ecological specialization, we mimicked evolution in vitro by sub-culturing the atrazine-degrading Pseudomonas sp. ADP in a liquid medium containing cyanuric acid as the sole source of nitrogen. After 120 generations, a new population evolved, which replaced the original on…
Toward an integrated approach for studying plant-microbe interactions in the rhizosphere: from genomic to proteomic
2006
International audience
Compte rendu de : Christophe Regina, Genre, mœurs et justice. Les Marseillaises et la violence au XVIIIe siècle, Aix-en-Provence, Presses universitai…
2017
International audience
L’égalité sans condition : une utopie réaliste en EPS ?
2020
International audience
Mixité, égalité et pratiques en éducation physique et sportive : introduction
2020
International audience
Mixité, égalité et pratiques en éducation physique et sportive
2022
« Mixité, égalité et pratiques », ce triptyque pourra en apparence manquer d’originalité pour qui aurait un peu de familiarité aux travaux sur l’Éducation physique et sportive (EPS) en Sciences de l’éducation et de la formation (SEF) ou en Sciences et techniques des activités physiques et sportives (STAPS). Puisqu’il s’agit d’une indéniable ultime redite, le choix du titre de ce dossier mérite au moins deux réflexions : l’une appelle à y trouver un certain immobilisme disciplinaire, et plus largement scolaire, sur le mode « rien n’a changé, les inégalités collent à la mixité et à la différence des corps sexués » ; l’autre y voit, comme Pénélope durant l’absence d’Ulysse, un ouvrage sans ces…
La femme est-elle l’avenir du film ? Les mutations à l’œuvre dans La piel que habito (Pedro Almodóvar, 2011) et Laurence anyways (Xavier Dolan, 2012)
2013
International audience